Lambert Eaton Myasthenic Syndrome is a autoimmune disease whereby antibodies attack and destroy ...
Presynaptic Vesicles
Presynaptic Calcium Channels
Postsynaptic Receptors
Lambert Eaton Myasthenic Syndrome typically causes muscle weakness in which parts of the body?
Distal limbs (arms and legs)
Proximal limbs (arms and legs)
Typically legs only
Typically arms only
60% of patients with Lambert-Eaton Myasthenic Syndrome have an underlying malignancy. Which malignancy does it most commonly present with?
Small cell lung cancer
Adenocarcinoma of the lung
Squamous cell lung cancer
Large cell lung cancer
Breast cancer
Renal cancer
What is the most common disorder of the neuromuscular junction?
Lambert-Eaton Myasthenic Syndrome
Myasthenia Gravis
Neuromyotonia
Congenital Myasthenia
Myasthenia Gravis is an autoimmune condition whereby the body develops autoantibodies against receptors
Symptoms of Myasthenia Gravis only tend to start once ACh receptors are reduced to 30 60 5( 30, 60, 5 )% of normal
Which of the following structures is also known to play a part in Myasthenia Gravis?
Thymus
Bone Marrow
Thalamus
Pituitary Gland
Adrenal Gland
Males tend to typically present with Myasthenia Gravis in their 30s whereas woman tend to present in their 60s-70s
The difference between Myasthenia Gravis and Lambert-Eaton Myasthenic Syndrome is that ...
Myasthenia Gravis tends to present mostly in the proximal legs, but not the arms.
Myasthenia Gravis tends to present mostly in the proximal arms, but not the legs.
Whilst Myasthenia Gravis typically presents with proximal weakness of the proximal leg muscles, it also tends to cause weakness in which of the following?
Extraocular muscles
Facial muscles
Carpal muscles
Tarsal muscles
Abdominal muscles
Investing fascia muscles
The initial therapy for most patients with myasthenia gravis is an oral acetylcholinesterase inhibitor, usually Pyridostigmine Physostigmine Neostigmine Rivastigmine( Pyridostigmine, Physostigmine, Neostigmine, Rivastigmine )
Aminoglycoside antibiotics impair neuromuscular transmission and can cause clinically significant muscle weakness, resulting in respiratory depression in myasthenia gravis patients. Therefore, which of the following medications should be avoided in such patients?
Gentamicin
Ceftriaxone
Amoxicillin
Metronidazole
Doxycycline
Inability to relax voluntary muscle after vigorous effort is known as .
Rhabdomyolysis releases high amounts of into the plasma thus causing Acute Kidney Injury (AKI)
