Kathleen Jackson
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EoT Exam Module 5 & 6

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Kathleen Jackson
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2808NRS Human Pathophysiology and Pharmacology 2 (Module 5 & 6)

Frage 1 von 76

1

The tendency to involuntarily pass urine, usually in small amounts, when abdominal pressure is raised during coughing, for example, is termed:

Wähle eine der folgenden:

  • urge incontinence

  • neurological incontinence

  • stress incontinence

  • overflow incontinence

Erklärung

Frage 2 von 76

1

Which diuretics promote the greatest diuresis?

Wähle eine der folgenden:

  • Thiazides.

  • Potassium-sparing diuretics.

  • Aldosterone inhibitors.

  • Loop diurectics.

Erklärung

Frage 3 von 76

1

Turbid urine normally indicates:

Wähle eine der folgenden:

  • kidney stones

  • diabetes

  • infection

  • dehydration

Erklärung

Frage 4 von 76

1

Which is most likely to contribute to overflow incontinence?

Wähle eine der folgenden:

  • kidney stones lodged in the renal calyxes

  • glomerulonephritis

  • prostate enlargement

  • urethritis

Erklärung

Frage 5 von 76

1

Azotaemia describes increased concentrations of:

Wähle eine der folgenden:

  • nitrogen waste compounds in blood

  • urea in urine

  • potassium and sodium levels in blood

  • azotaemia is, in fact, an alternative term for uraemic frost

Erklärung

Frage 6 von 76

1

From the following, choose the substance likely to appear in the urine when the glomerulus is inflamed.

Wähle eine der folgenden:

  • Creatinine

  • Urea

  • Sodium

  • Albumin

Erklärung

Frage 7 von 76

1

When comparing normal kidney function with dialysis, which of the following mechanisms is not possible in dialysis?

Wähle eine der folgenden:

  • Diffusion

  • Active transport

  • Ultrafiltration

  • Osmosis

Erklärung

Frage 8 von 76

1

Which of the following should be present in the filtrate in the proximal convoluted tubule?

Wähle eine der folgenden:

  • Erythrocytes

  • Leukocytes

  • Glucose molecules

  • Plasma proteins

Erklärung

Frage 9 von 76

1

Common causes of urolithiasis include all of the following EXCEPT:

Wähle eine der folgenden:

  • hypercalcemia.

  • hyperlipidemia.

  • inadequate fluid intake.

  • hyperuricemia.

Erklärung

Frage 10 von 76

1

Which of the following increases glomerular filtration rate?

Wähle eine der folgenden:

  • Constriction of the afferent arteriole

  • Increased hydrostatic pressure in the glomerular capillaries

  • Dilation of the efferent arteriole

  • Increased plasma osmotic pressure

Erklärung

Frage 11 von 76

1

Reducing fluid intake is non-pharmacological advice designed to decrease the incidence of urinary tract infections.

Wähle eins der folgenden:

  • WAHR
  • FALSCH

Erklärung

Frage 12 von 76

1

Infection and inflammation of the bladder is termed:

Wähle eine der folgenden:

  • cystitis

  • urethritis

  • pyelonephritis

  • any of the above, depending on the origin of the infection

Erklärung

Frage 13 von 76

1

The incidence of urinary tract infections is about the same in women and in men, but treatment is more frequently sought by women.

Wähle eins der folgenden:

  • WAHR
  • FALSCH

Erklärung

Frage 14 von 76

1

Requesting patients to produce a mid-stream urine sample is designed to ensure the sample is not diluted by urine that has accumulated at the base of the bladder and in the urethra.

Wähle eins der folgenden:

  • WAHR
  • FALSCH

Erklärung

Frage 15 von 76

1

Under normal circumstances urine in the bladder is sterile, but it may be contaminated with bacteria upon exiting the urethra.

Wähle eins der folgenden:

  • WAHR
  • FALSCH

Erklärung

Frage 16 von 76

1

What is the cause of most cases of pyelonephritis?

Wähle eine der folgenden:

  • Severe pH imbalance of urine

  • Dialysis or other invasive procedure

  • An ascending infection by E. coli

  • Abnormal immune response, causing inflammation

Erklärung

Frage 17 von 76

1

What is the first indicator in the arterial blood gases of acidosis caused by glomerulonephritis?

Wähle eine der folgenden:

  • Increased carbonic acid

  • Increased bicarbonate ion

  • Decreased bicarbonate ion

  • A pH less than 7.35

Erklärung

Frage 18 von 76

1

Which of the following would be considered normal serum pH?

Wähle eine der folgenden:

  • 7.0

  • 7.4

  • 8

  • 4.5 - 8

Erklärung

Frage 19 von 76

1

In a case of acute pyelonephritis, what is the cause of flank pain?

Wähle eine der folgenden:

  • Increasing glomerular permeability, creating an increased volume of filtrate in the kidney

  • Inflammation, causing ischemia in the tubules

  • Inflammation, stretching the renal capsule

  • Microbes irritating the tissues

Erklärung

Frage 20 von 76

1

Pyelonephritis may be distinguished from cystitis by the presence in pyelonephritis of:

Wähle eine der folgenden:

  • urinary casts and flank pain.

  • painful micturition.

  • microbes, leukocytes, and pus in the urine.

  • urgency and frequency.

Erklärung

Frage 21 von 76

1

An elderly male patient produced only 25 mL of urine in the past 24 hours. The urologist discovers that prostatic hypertrophy is the cause. Which one of the following best describes this patient's acute renal failure?

Wähle eine der folgenden:

  • Postrenal oliguric

  • Prerenal anuric

  • Postrenal anuric

  • Intrinsic nonoliguric

Erklärung

Frage 22 von 76

1

Which one of the following electrolytes usually must be restricted in patients with acute renal failure?

Wähle eine der folgenden:

  • Potassium

  • Bicarbonate

  • Calcium

  • Chloride

Erklärung

Frage 23 von 76

1

Intrinsic acute kidney injury can be identified/caused by?

Wähle eine der folgenden:

  • decreased creatinine

  • a blockage of the renal artery

  • glomerulonephritis

  • haemorrhage

Erklärung

Frage 24 von 76

1

What is the definition of acute kidney injury?

Wähle eine der folgenden:

  • A drop in serum creatinine to less than or equal to 26 umol/L within 48 hours.

  • An increase in urine output to greater than 0.5 mL/kg/hr for 6 consecutive hours.

  • A rise in serum creatinine to greater than or equal to 26 umol/L within 48 hours.

  • An decrease in urine output to greater than 0.5 mL/kg/hr for 6 consecutive hours.

Erklärung

Frage 25 von 76

1

Which of the following indicates the early stage of acute renal failure?

Wähle eine der folgenden:

  • Very low GFR and increased serum urea

  • Hypotension and increased urine output

  • Development of decompensated acidosis

  • Polyuria with urine of fixed and low specific gravity

Erklärung

Frage 26 von 76

1

What is/are a cause(s) of acute tubule necrosis and acute renal failure?

Wähle eine der folgenden:

  • Sudden significant exposure to nephrotoxins

  • Prolonged circulatory shock

  • Crush injuries or burns

  • All of the above

Erklärung

Frage 27 von 76

1

What is the primary reason for hypocalcemia developing during end-stage renal failure or uremia?

Wähle eine der folgenden:

  • Insufficient calcium in the diet

  • A deficit of activated vitamin D and hyperphosphatemia

  • Excessive excretion of calcium ions in the urine

  • Decreased parathyroid hormone secretion

Erklärung

Frage 28 von 76

1

Which of the following would likely cause chronic renal failure?

Wähle eine der folgenden:

  • Circulatory shock

  • Diabetes mellitus

  • Cystitis with pyelonephritis in the right kidney

  • Obstruction of a ureter by a renal calculus

Erklärung

Frage 29 von 76

1

What causes polyuria during the stage of renal insufficiency?

Wähle eine der folgenden:

  • Loss of tubule function

  • Increased GFR

  • Increased blood pressure

  • Decreased aldosterone secretion

Erklärung

Frage 30 von 76

1

Insensible water loss occurs from ________, and ________.

Wähle eine der folgenden:

  • irregular incidents, such as vomiting as output can vary greatly

  • faeces; accounts for approximately 15% of normal daily output

  • kidneys; accounts for approximately 35% of normal daily output

  • lungs and skin; accounts for approximately 30% of normal daily output

Erklärung

Frage 31 von 76

1

Fluid load in patients may be increased, inadvertently or purposely, by:

Wähle eine der folgenden:

  • rectal solutions

  • enteral feeding

  • peritoneal dialysis

  • all of the above

Erklärung

Frage 32 von 76

1

Which condition will induce cell shrinking?

Wähle eine der folgenden:

  • when interstitial fluid is hypertonic

  • when interstitial fluid is hypotonic

  • when interstitial fluid is isotonic

  • all of the above

Erklärung

Frage 33 von 76

1

An athlete who has lost a litre or more of fluid via sweating is best advised to replace this with a solution that contains both salts and water, and a total osmolarity of approximately:

Wähle eine der folgenden:

  • 5.8 mOsmols

  • 90 mOsmols

  • 280 mOsmols

  • 560 mOsmols

Erklärung

Frage 34 von 76

1

A clinical use of a hypertonic solution is:

Wähle eine der folgenden:

  • To correct whole blood loss with mild hypvolaemia

  • Dehydrated patients with severe hypernatremia

  • Treat severe intracellular dehydration

  • Treating cerebral oedema and intracranial hypertension

Erklärung

Frage 35 von 76

1

Which of the following is an example of an isotonic solution?

Wähle eine der folgenden:

  • 0.45% sodium chloride.

  • 4% glucose with 0.18% sodium chloride.

  • 10% glucose.

  • 25% mannitol.

Erklärung

Frage 36 von 76

1

Which of the following is an example of an hypotonic solution?

Wähle eine der folgenden:

  • 0.9% sodium chloride

  • 25% mannitol

  • Water

  • Whole blood

Erklärung

Frage 37 von 76

1

A 70-year-old male with chronic renal failure presents with oedema. Which of the following is the most likely cause of this condition?

Wähle eine der folgenden:

  • increased interstitial oncotic pressure

  • decreased capillary oncotic pressure

  • increased capillary oncotic pressure

  • decreased capillary hydrostatic pressure

Erklärung

Frage 38 von 76

1

A 10-year-old male is brought to the ED because he is incoherent and semiconscious. CT scan reveals he is suffering from cerebral oedema. This type of oedema is referred to as:

Wähle eine der folgenden:

  • pitting oedema

  • localised oedema

  • generalised oedema

  • pulmonary oedema

Erklärung

Frage 39 von 76

1

Insensible fluid loss refers to water lost through:

Wähle eine der folgenden:

  • faeces only

  • perspiration only

  • urine and faeces

  • perspiration and expiration

Erklärung

Frage 40 von 76

1

A 35-year-old male weighs 70 kg. Approximately how much of this weight is intracellular fluid?

Wähle eine der folgenden:

  • 5 L

  • 10 L

  • 28 L

  • 42 L

Erklärung

Frage 41 von 76

1

A 5-year-old male presents to the ED with delirium and sunken eyes. After diagnosing him with severe dehydration, the doctor orders fluid replacement. The nurse administers a hypertonic IV solution. Which of the following would be expected?

Wähle eine der folgenden:

  • his symptoms would subside quickly

  • decreased extracellular fluid volume

  • intracellular dehydration

  • increased intracellular fluid volume

Erklärung

Frage 42 von 76

1

Which of the following is a common cause of hyponatraemia?

Wähle eine der folgenden:

  • Prolonged period of rapid, deep respirations

  • Excessive sweating

  • Loss of the thirst mechanism

  • Excessive aldosterone secretion

Erklärung

Frage 43 von 76

1

Which of the following ions is most closely related to water movement?

Wähle eine der folgenden:

  • Potassium

  • Sodium

  • Chloride

  • Calcium

Erklärung

Frage 44 von 76

1

Which of the following is the primary cation in the extracellular fluid?

Wähle eine der folgenden:

  • Bicarbonate

  • Potassium

  • Chloride

  • Sodium

Erklärung

Frage 45 von 76

1

Which compartment contains the greatest amount of body water

Wähle eine der folgenden:

  • Intracellular

  • Interstital

  • Plasma

  • Transcellular

Erklärung

Frage 46 von 76

1

When a patient is being treated with thiazide diuretics, there is a danger of ________, an unwanted and potentially dangerous side effect.

Wähle eine der folgenden:

  • hypocalcaemia

  • hypokalaemia

  • hypophosphataemia

  • hyponatraemia

Erklärung

Frage 47 von 76

1

Hyperkalaemia causes:

Wähle eine der folgenden:

  • a decrease in resting membrane potential with increased excitability of cardiac muscle.

  • a decrease in resting membrane potential with decreased excitability of cardiac muscle.

  • an increase in resting membrane potential with decreased excitability of cardiac muscle.

  • an increase in resting membrane potential with increased excitability of cardiac muscle.

Erklärung

Frage 48 von 76

1

Which of the following would most likely cause hypochloraemia?

Wähle eine der folgenden:

  • hypokalaemia

  • hypernataemia

  • elevated bicarbonate

  • hypercalcaemia

Erklärung

Frage 49 von 76

1

A 42-year-old female presents to her GP complaining of muscle weakness and cardiac abnormalities. Laboratory tests indicate that she is hypokalaemic. Which of the following could be the cause of her condition?

Wähle eine der folgenden:

  • hypoglycaemia

  • respiratory acidosis

  • constipation

  • frusemide therapy

Erklärung

Frage 50 von 76

1

Secretion of aldosterone results in:

Wähle eine der folgenden:

  • decreased plasma osmolality.

  • increased blood volume.

  • increased serum potassium levels.

  • localised oedema.

Erklärung

Frage 51 von 76

1

Metabolic acidosis may be associated with

Wähle eine der folgenden:

  • Increased chloride levels

  • Decreased bicarbonate

  • Increased metabolic acids

  • All answers are correct

Erklärung

Frage 52 von 76

1

Chronic compensation for respiratory acidosis includes:

Wähle eine der folgenden:

  • kidney excretion of HCO3-

  • kidney excretion of H+

  • protein buffering

  • prolonged exhalations to blow off CO2

Erklärung

Frage 53 von 76

1

Which of the following is a strong acid?

Wähle eine der folgenden:

  • Phosphorus

  • Albumin

  • Sodium chloride

  • Lactate

Erklärung

Frage 54 von 76

1

Long-term regulation of acid-base balance through removal or retention of acids is accomplished by the:

Wähle eine der folgenden:

  • lungs

  • kidneys

  • liver

  • protein buffer systems

Erklärung

Frage 55 von 76

1

Which of the following buffer pairs is considered the major plasma buffering system?

Wähle eine der folgenden:

  • NH3/NH4

  • NaCl/KPO4

  • HCO3-/H2CO3

  • HPO4/H2PO4

Erklärung

Frage 56 von 76

1

Autoregulation in the kidneys refers to:

Wähle eine der folgenden:

  • the control of systemic blood pressure by the kidneys.

  • control of blood flow by the SNS.

  • the secretion of renin and activation of angiotensin.

  • local minor reflex adjustments in the arterioles to maintain normal blood flow.

Erklärung

Frage 57 von 76

1

Place the following events in the correct sequence of events when ketoacids increase in the blood of a diabetic patient.
Not all options are used in the answers.
1. Serum pH decreases
2. Serum bicarbonate decreases
3. PCO2 decreases
4. Respiration decreases
5. Respiration increases
6. Serum pH increases
7. Serum bicarbonate increases

Wähle eine der folgenden:

  • 7, 6, 5, 3, 6

  • 2, 6, 5, 3, 7

  • 7, 6, 4, 3, 1

  • 2, 1, 5, 3, 6

Erklärung

Frage 58 von 76

1

Which condition is likely to cause metabolic acidosis?

Wähle eine der folgenden:

  • Slow, shallow respirations

  • Excessive fluid in the body

  • Prolonged diarrhoea

  • Mild vomiting

Erklärung

Frage 59 von 76

1

A 55-year-old female presents to her GP complaining of dizziness, confusion and tingling in the extremities. Blood tests reveal an elevated pH, decreased PCO2 and slightly decreased HCO3-. Which of the following is the most likely diagnosis?

Wähle eine der folgenden:

  • respiratory alkalosis with renal compensation

  • respiratory acidosis with renal compensation

  • metabolic alkalosis with respiratory compensation

  • metabolic acidosis with respiratory compensation

Erklärung

Frage 60 von 76

1

Which serum value indicates decompensated metabolic acidosis?

Wähle eine der folgenden:

  • Bicarbonate level increases

  • Bicarbonate level decreases

  • pH is above normal range

  • pH is below normal range

Erklärung

Frage 61 von 76

1

Acute compensation for metabolic acidosis includes:

Wähle eine der folgenden:

  • CO2 retention.

  • kidney excretion of H+.

  • hyperventilation.

  • hypoventilation.

Erklärung

Frage 62 von 76

1

A 52-year-old male with diabetes presents to the ED with lethargy, confusion and depressed reflexes. His wife indicates that he does not follow the prescribed diet and takes his medication sporadically. Which of the following is most likely to occur?

Wähle eine der folgenden:

  • diabetes insipidus

  • decreased extracellular fluid osmolality

  • hyponatraemia

  • decreased urine formation

Erklärung

Frage 63 von 76

1

Uncontrolled essential hypertension may cause chronic renal failure because of:

Wähle eine der folgenden:

  • damage to afferent arterioles and renal ischemia.

  • failure of tubules to respond to hormonal controls.

  • glomerular congestion causes damaged capillaries.

  • predisposition to recurrent urinary tract infections.

Erklärung

Frage 64 von 76

1

In chronic renal failure, which of the following is the most immediately dangerous?

Wähle eine der folgenden:

  • acidosis

  • phosphataemia

  • haematuria

  • anaemia

Erklärung

Frage 65 von 76

1

Which of the following causes acute renal failure?

Wähle eine der folgenden:

  • Nephrosclerosis

  • Bilateral acute glomerulonephritis

  • Polycystic kidney disease

  • Pyelonephritis in the right kidney

Erklärung

Frage 66 von 76

1

Which of the following is a typical sign of dehydration?

Wähle eine der folgenden:

  • Rapid, strong pulse

  • Low haematocrit

  • Increased urine output

  • Decreased tissue turgor

Erklärung

Frage 67 von 76

1

The normal pH of urine is:

Wähle eine der folgenden:

  • 1.5-5.5.

  • 4.5- 8.0.

  • 7.35-7.45.

  • 7.0-10.

Erklärung

Frage 68 von 76

1

Which of the following conditions would decrease oncotic pressure in the capillaries?

Wähle eine der folgenden:

  • low blood pressure

  • high-protein diet

  • liver failure

  • high blood-glucose

Erklärung

Frage 69 von 76

1

Chronic renal failure adversely affects which body system?

Wähle eine der folgenden:

  • the cardiovascular system

  • the respiratory system

  • the CNS

  • All answers are correct

Erklärung

Frage 70 von 76

1

Infants are at a higher risk for developing dehydration because they have:

Wähle eine der folgenden:

  • a lower total body water volume.

  • a decreased intravascular volume.

  • a greater body surface area.

  • an increased tendency towards developing oedema.

Erklärung

Frage 71 von 76

1

Which of the following would result in hyperkalaemia?

Wähle eine der folgenden:

  • insulin

  • excess aldosterone

  • acute acidosis

  • alkalosis

Erklärung

Frage 72 von 76

1

Which of the following results from decreased blood flow into the kidneys?

Wähle eine der folgenden:

  • Systemic blood pressure drop

  • Dilation of the afferent arterioles

  • Increased angiotensin and systemic vasoconstriction

  • Decreased aldosterone secretion

Erklärung

Frage 73 von 76

1

Which of the following alterations would result in fluid movement into the interstitial space?

Wähle eine der folgenden:

  • increased interstitial hydrostatic pressure

  • decreased capillary hydrostatic pressure

  • increased capillary oncotic pressure

  • decreased capillary oncotic pressure

Erklärung

Frage 74 von 76

1

Causes of respiratory acidosis include:

Wähle eine der folgenden:

  • hyperventilation.

  • an increase in noncarbonic acids.

  • pneumonia.

  • vomiting.

Erklärung

Frage 75 von 76

1

Crush injuries associated with a massive degree of cell rupture are likely to increase levels of extracellular:

Wähle eine der folgenden:

  • potassium

  • calcium

  • sodium

  • phosphate

Erklärung

Frage 76 von 76

1

Choose the basic cause of bone remodelling disorders associated with chronic renal failure.

Wähle eine der folgenden:

  • Excessive loss of phosphate ion

  • Deficit of parathyroid hormone

  • Failure of the kidney to activate vitamin D

  • Development of hypercalcemia

Erklärung