Matthew Coulson
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Neurobiology of Addiction lecture given on 05/10/2018

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Matthew Coulson
Erstellt von Matthew Coulson vor fast 6 Jahre
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Neurobiology of Addiction

Frage 1 von 9

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The reward pathway, in the most basic sense, begins in the floor of the midbrain at the (clue: VTA), which then projects to the . This structure then projects finally to the cortex.

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Frage 2 von 9

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The reward pathway is also known as the

Wähle eine der folgenden:

  • Mesolimbic Pathway

  • Mesocortical Pathway

  • Nigrostriatal Pathway

  • Tuberoinfundibular Pathway

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Frage 3 von 9

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The mesolimbic pathway is one of the four ...

Wähle eine der folgenden:

  • Dopaminergic Pathways

  • Adrenergic Pathways

  • Glutamatergic Pathways

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Frage 4 von 9

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In terms of the nucleus accumbens, overexpression of which gene transcription factor is thought to be the main influencer of addiction?

Wähle eine der folgenden:

  • ΔFosB

  • ΔJunD

  • cAMP

  • CREB

  • NFκB

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Frage 5 von 9

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Patients showing addictive behaviours tend to have a preserved insight; they know they are unwell.

Wähle eins der folgenden:

  • WAHR
  • FALSCH

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Frage 6 von 9

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Dopamine release usually has the ability to update info and set new goals in the prefrontal cortex, thus having the ability to avoid compulsive repetition of a behaviour. Addictive drugs provide a potent dopamine signal which disrupts the normal dopamine learning pathway in the prefrontal cortex.

Wähle eins der folgenden:

  • WAHR
  • FALSCH

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Frage 7 von 9

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On average, those who start experimenting with drugs earlier in life tend to have a shorter relationship with drugs.

Wähle eins der folgenden:

  • WAHR
  • FALSCH

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Frage 8 von 9

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Which part of the frontal cortex concerns the following:
Emotion and reward in decision making; hyperactivity of this area during addiction behaviour represents craving

Wähle eine der folgenden:

  • Orbitofrontal Cortex

  • ‎Ventrolateral Prefrontal Cortex

  • ‎Dorsolateral Prefrontal Cortex

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Frage 9 von 9

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In ( non-addicted, addicted ) brains, areas such as the Anterior Cingulate Gyrus send inhibitory signals to the orbitofrontal cortex and thus the sensation of craving ( does not, does ) occur.
In ( addicted, non-addicted ) brains, the nucleus accumbens sends inhibitory signals to areas such as the Anterior Cingulate Gyrus so that the inhibitory signals are not sent to the Orbitofrontal cortex and thus the sensation of craving ( does, does not ) occur

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