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3 Microbiology 305 Quiz am Secretion and Adhesion System Questions, erstellt von Amanda A am 08/11/2018.

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Secretion and Adhesion System Questions

Secretion and Adhesion System Questions

Frage 1 von 17

1

Cholera toxin is secreted by a mechanism that mimics what process

Wähle eine der folgenden:

  • Type I pilus formation

  • Flagellar synthesis

  • Conjugation

  • Type IV pilus formation

Erklärung

Frage 2 von 17

1

Which secretion system has a needle complex for injection of bacterial toxins into the host cell?

Wähle eine der folgenden:

  • Type I

  • Type II

  • Type III

  • Type IV

Erklärung

Frage 3 von 17

1

Which species injects a receptor for the adhesin intimin into the host cell?

Wähle eine der folgenden:

  • Bordetella pertussis

  • Salmonella typhimurium

  • Bacillus anthracis

  • Vibrio cholerae

  • Escherichia coli

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Frage 4 von 17

1

How does Shigella enter the host cell?

Wähle eine der folgenden:

  • It binds and invade the cell by secreting proteases to digest the host cell membrane

  • It secretes factors that cause host cell apoptosis

  • It secretes factors that cause the host cell membrane to be smooth and thin, enabling invasion

  • It injects proteins that change the host cell cytoskeleton, causing engulfment of the bacteria

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Frage 5 von 17

1

Fülle die Lücken, um den Text zu vervollständigen.

Adherence
Type I:
Type IV:

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Frage 6 von 17

1

Match the category of exotoxin to the correct example.

Staphylococcus aureus alpha toxin
Vibrio cholerae RTX toxin
Diphtheria toxin
E. coli cytolethal distending toxin
Cholera toxin
Staphylococcus aureus exfoliative toxin
Helicobacter pylori VacA toxin
Tetanus toxin
Staphylococcus auerus and Streptococcus pyogenes pyrogenic toxins

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    Plasma membrane disruption
    Cytoskeleton alterations
    Protein synthesis disruption
    Cell cycle disruption
    Signal transduction disruption
    Cell-cell adherence
    Vesicle traffic
    Exocytosis
    Superantigens

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Frage 7 von 17

1

Which secretion system uses a conjugation-like machinery to secrete protein from cytoplasm or periplasm?

Wähle eine der folgenden:

  • Type I

  • Type II

  • Type III

  • Type IV

Erklärung

Frage 8 von 17

1

Which secretion system uses molecular syringe to inject proteins from bacterial cytoplasm into host cytoplasm?

Wähle eine der folgenden:

  • Type I

  • Type II

  • Type III

  • Type IV

Erklärung

Frage 9 von 17

1

What type of secretion system uses pilus-like extraction/retraction mechanism to push proteins out of the cell

Wähle eine der folgenden:

  • Type I

  • Type II

  • Type III

  • Type IV

Erklärung

Frage 10 von 17

1

Fülle die Lücken, um den Text zu vervollständigen.

, , and are all examples of structures used by microbes for adhesion.

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Frage 11 von 17

1

You have recently identified a new toxin. It is produced by a gram-negative bacterium. It is composed mostly of protein, has high toxicity, and is not heat stable. You also discover that it targets liver cells. Based on these characteristics, how would you classify this toxin?

Wähle eine der folgenden:

  • Superantigen

  • Endotoxin

  • Exotoxin

  • Leukocidin

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Frage 12 von 17

1

You have recently identified a new toxin. It is produced by a gram-negative bacterium. It is composed mostly of polysaccharides, binds to immune cells, and triggers fevers. Based on these characteristics, how would you classify this toxin?

Wähle eine der folgenden:

  • Superantigen

  • Endotoxin

  • Exotoxin

  • Adhesin

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Frage 13 von 17

1

Match the toxin to its secretion system.

Uses molecular syringe to inject proteins from bacterial cytoplasm into host cytoplasm
Uses a conjugation-like machinery to secrete protein from cytoplasm or periplasm
Uses pilus-like extraction/retraction mechanism to push proteins out of the cell
Uses ABC mechanisms that move certain secreted proteins directly out of the cell

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    Salmonella typhimurium
    Type III
    Pertussis toxin
    Type IV
    Cholera toxin
    Type II
    E. coli alpha hemolysin
    Type I

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Frage 14 von 17

1

4. Which of the following pathogens does not have endotoxin?

Wähle eine der folgenden:

  • Bacillus anthracis

  • Yersinia pestis

  • Vibro cholerae

  • Salmonella typhimurium

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Frage 15 von 17

1

If SecA were mutated, E. coli could adhere to renal cells but would be unable to secrete exotoxins to cause infection.

Wähle eins der folgenden:

  • WAHR
  • FALSCH

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Frage 16 von 17

1

15. How does the plague bacterium survive the immune response?

Wähle eine oder mehr der folgenden:

  • Antigenic variance of its distinguishing surface features

  • Injecting exotoxins that kill macrophages

  • Forming spores to survive phagocytosis

  • Silencing pro-inflammatory cytokines

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Frage 17 von 17

1

You observe a protein structure that has two subunits and is involved in bacterial pathogenesis. This protein is most likely which of the following?

Wähle eine der folgenden:

  • Host cell receptor

  • Capsid protein

  • Exotoxin

  • Endotoxin

  • Pili subunit

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