Breast Pathology I

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Match the biopsy techniques to their field:
Fine Needle Aspiration = ❌
Core Needle Biopsy = ❌

Histology

Cytopathology

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Which is most commonly utilised mode of biopsy in terms of retrieving breast tissue?

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( Histological, Cytological ) biopsy techniques allow a clinician to assess whether a malignant cancer is in situ or invasive.
This is not available when utilising a ( Cytological, Histological ) technique of biopsy.

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Excessive growth of the breasts during puberty is known as juvenile breast

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Enlargement of a man's breasts, usually due to hormone imbalance or hormone therapy is known as

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Gynaecomastia involves ductal growth within the breast ( without, with ) associated lobular development

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Excessive cannabis use is a known cause of gynaecomastia

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Having ( liver, kidney, heart, crohn's ) disease is a risk factor for developing gynaecomastia

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Women between the ages of 20-50 (majority 40-50) commonly develop benign breast lumps due to fibrous tissue aggregates in an area of the breast.
What is this known as?

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Fibrocystic change occurs in around ( one third, a half, one quarter, three quarters ) of women at some point in their lifetime (typically 40-50)

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Fibrocystic changes in women typically subside or reduce following menopause.

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Fibrocystic changes are usually painless.

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What is the difference between cytology and histology?
❌ = Study of individual cells
❌ = Study of tissues

Histology

Cytology

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Which two of the following are known risk factors for breast cancer development?

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Despite being associated with breast cancer, early menarche and late menopause are also associated with fibrocystic changes.

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Which, if any, of the following conditions is painful?
Fibrocystic Change: ( Painful, Painless )
Fibroadenoma: ( Painless, Painful )

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Fibrocystic change usually occurs as development of a single solitary mass.

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What is the typical management of fibrocystic change?

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Fibrocystic changes are known to commonly develop into breast cancer

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Name the condition:
"A circumscribed benign lesion composed of tissues normal to the breast (adipose, glandular and connective) but organised in an abnormal proportion or distribution"

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Fibroadenomas typically occur as a single solitary lesion.

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Occurs as multiple lesions: ( Fibrocystic Change, Fibroadenoma )
Occurs as single lesion: ( Fibroadenoma, Fibrocystic Change )
Typically painless: ( Fibroadenoma, Fibrocystic Change )
Typically painful: ( Fibrocystic Change, Fibroadenoma )

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Fibroadenoma is more common in women of asian origin.

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Fibroadenomas most commonly present in a woman's ( 30s, 20s, 40s )

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Fibroadenomas are typically ( mobile, immobile ) lesions

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When seeing woman with suspicious breast lesions, their age defines which type of scan they should have:
A woman under the age of ( 40, 30, 50 ) should have ( an Ultrasound Scan, a Mammogram )
A woman over the age of ( 40, 30, 50 ) should have ( a Mammogram, an Ultrasound Scan )

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How are fibroadenomas typically managed?

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Malignant breast cancers are typically solid and fixed within the breast.

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is a benign proliferative condition of the terminal duct lobular units characterised by an increased number of acini and their glands. This may cause a mass or calcification within the breast which can be mistaken for a breast cancer.

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Sclerosing Adenosis should be excised as soon as possible following diagnosis due to the risk that it may undergo malignant change.

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A complex sclerosing lesion of the breast is a benign breast lesion that can radiologically mimic malignancy. Clinically, this is known as a scar

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A ( Radial Scar, Sclerosing Adenosis ) is more serious as it can progress to invasive carcinoma. It should therefore the excised or at least extensively sampled.

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Which two of the following biopsy techniques are typically utilised in the diagnosis of a radial scar?

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Which of the following conditions most commonly occurs due to local trauma, for example a seat belt injury?

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Which anticoagulant drug is also known to cause fat necrosis of the breast?

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Which of the following conditions is very highly associated with a long smoking history?

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Which inflammatory breast condition is associated with smoking and causes fistulas to open up around the nipple?

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Duct ectasia is typically very painful and produces bloody and/or purulent discharge

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Which 3 of the following features typically occur as part of duct ectasia?

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Which three of the following are common interventions for duct ectasia?

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Which 2 of the following bacteria are typically involved in mastitis due to breast-feeding?

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Breast pathology I lecture given on 07/01/2019

Breast Pathology I

Match the biopsy techniques to their field: Fine Needle Aspiration = ❌ Core Needle Biopsy = ❌

Which is most commonly utilised mode of biopsy in terms of retrieving breast tissue?

Histological Cytological( Histological, Cytological ) biopsy techniques allow a clinician to assess whether a malignant cancer is in situ or invasive. This is not available when utilising a Cytological Histological( Cytological, Histological ) technique of biopsy.

Excessive growth of the breasts during puberty is known as juvenile breast

Enlargement of a man's breasts, usually due to hormone imbalance or hormone therapy is known as

Gynaecomastia involves ductal growth within the breast without with( without, with ) associated lobular development

Excessive cannabis use is a known cause of gynaecomastia

Having liver kidney heart crohn's( liver, kidney, heart, crohn's ) disease is a risk factor for developing gynaecomastia

Women between the ages of 20-50 (majority 40-50) commonly develop benign breast lumps due to fibrous tissue aggregates in an area of the breast. What is this known as?

Fibrocystic change occurs in around one third a half one quarter three quarters( one third, a half, one quarter, three quarters ) of women at some point in their lifetime (typically 40-50)

Fibrocystic changes in women typically subside or reduce following menopause.

Fibrocystic changes are usually painless.

What is the difference between cytology and histology? ❌ = Study of individual cells ❌ = Study of tissues

Which two of the following are known risk factors for breast cancer development?

Despite being associated with breast cancer, early menarche and late menopause are also associated with fibrocystic changes.

Which, if any, of the following conditions is painful? Fibrocystic Change: Painful Painless( Painful, Painless ) Fibroadenoma: Painless Painful( Painless, Painful )

Fibrocystic change usually occurs as development of a single solitary mass.

What is the typical management of fibrocystic change?

Fibrocystic changes are known to commonly develop into breast cancer

Match the biopsy techniques to their field:
Fine Needle Aspiration = ❌
Core Needle Biopsy = ❌

( Histological, Cytological ) biopsy techniques allow a clinician to assess whether a malignant cancer is in situ or invasive.
This is not available when utilising a ( Cytological, Histological ) technique of biopsy.

Gynaecomastia involves ductal growth within the breast ( without, with ) associated lobular development

Having ( liver, kidney, heart, crohn's ) disease is a risk factor for developing gynaecomastia

Women between the ages of 20-50 (majority 40-50) commonly develop benign breast lumps due to fibrous tissue aggregates in an area of the breast.
What is this known as?

Fibrocystic change occurs in around ( one third, a half, one quarter, three quarters ) of women at some point in their lifetime (typically 40-50)

What is the difference between cytology and histology?
❌ = Study of individual cells
❌ = Study of tissues

Which, if any, of the following conditions is painful?
Fibrocystic Change: ( Painful, Painless )
Fibroadenoma: ( Painless, Painful )

Name the condition:
"A circumscribed benign lesion composed of tissues normal to the breast (adipose, glandular and connective) but organised in an abnormal proportion or distribution"

Fibroadenomas most commonly present in a woman's ( 30s, 20s, 40s )

Fibroadenomas are typically ( mobile, immobile ) lesions

A ( Radial Scar, Sclerosing Adenosis ) is more serious as it can progress to invasive carcinoma. It should therefore the excised or at least extensively sampled.