Haemolysis

The shape of a normal red cell is described as

Red blood cells have no mitochondria and thus rely on the process of for energy

When the body deals with increased red cell destruction by means of increased red cell production this is known as haemolysis.

Increased rate of red cell destruction exceeding bone marrow capacity for red cell production = Anaemia

Increased bone marrow red cell production is known as

When in suspicion of an immune-mediated hemolytic anemia, a clinician can confirm or deny this hypothesis by conducting a Coomb's Test

haemolysis: Immune response to nonself antigens from members of the same species
haemolysis: Immune response of an organism against its own healthy cells

Autoimmune Haemolysis can be either 'warm' or 'cold'
Warm Autoimmune Haemolysis is mediated by Ig
Cold Autoimmune Haemolysis is mediated by Ig

E.coli O157 infection can cause an anaemic state via destruction of RBCs, platelets all whilst bringing about kidney failure. This is called

Name the condition:
An inherited abnormality of the red blood cells whereby there are defects in the membrane structure, causing the formation of spherical red blood cells. These abnormal cells are removed by the spleen and thus have a very short lifespan, sometimes only around 10 days.
This condition is called

The normal lifespan of a red blood cell is around days.

Which drug, used primarily in the treatment of dermatitis herpetiformis, can cause a haemolytic anaemia?

Sickle cell disease is caused by a mutation in a globin chain.

Diagnose this patient:
A 22 year old female presented to the GP with intermittent mild jaundice which her partner had noticed. She has a PMX of gallstones and on examination she is found to have splenomegaly. Upon further questioning it was found that her father had had his spleen removed at a young age.
This woman is likely suffering from

These 'golf ball cells' that are labelled on the diagram are red blood cells with abnormal haemoglobin inside of them. If I told you that the patient was a young thai girl who has intermittent jaundice when she unwell, what would your diagnosis be?