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PHCY310 Quiz am L6 The parasympathetic nervous system and cholinergic neurotransmission, erstellt von Mer Scott am 06/04/2019.

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L6 The parasympathetic nervous system and cholinergic neurotransmission

Frage 1 von 7

1

Stimulation of the PNS is more organ specific, with discrete innervation. Ganglia are to the organs.
Parasympathetic pre-ganglionic nerve endings release , which acts on receptors. This is the as the sympathetic pre-ganglionic nerve endings.
Post-ganglionic nerve endings release ACh which acts on receptors. This is to the sympathetic post-ganglionic nerves as they release to act on receptors.
Remember, muscarinic receptors give slower responses.

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    closer
    ACh
    nicotinic
    same
    muscarinic
    different
    catecholamines
    adrenergic
    physiological

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Frage 2 von 7

1

Muscarinic receptors are G-protein coupled. Select the muscarinic receptors which have excitatory effects through IP3, instead of inhibitory effects through cAMP.

Wähle eine oder mehr der folgenden:

  • M1

  • M2

  • M3

  • M4

  • M5

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Frage 3 von 7

1

M1 receptors are , and found in the autonomic and enteric , gastric , and cortex. M2 receptors are cardiac, found in the . M3 receptors are glandular and smooth muscular innervating, and are found in glands, smooth muscle () and blood .
M4 and M5 are within the only.

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    neural
    ganglia
    cells
    cerebral
    SA and AV nodes
    exocrine
    GIT, eye, airways, bladder
    vessels
    CNS
    PNS

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Frage 4 von 7

1

Wähle von der Dropdown-Liste, um den Text zu vervollständigen.

Organ specific actions of the PNS:
Heart, via M2 stimulation:
( decreased, increased ) SA node firing
( decreased, increased ) AV node conduction
( decreased, increased ) heart rate, contractility, and CO
Lungs, via M3 stimulation
( constrict, relax ) bronchial muscle
( increase, decrease ) secretions
( decrease, increase ) airway diameter
Bladder, via M3 and M2 stimulation
( Contraction, Relaxation ) of detrusor
( Relax, Contract ) sphincter
• Micturition reflex

These effects are opposite to the SNS.

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Frage 5 von 7

1

Muscarinic agonists mimic the action of at muscarinic receptors. They are agonists at nicotinic and muscarinic receptors, but more potent at receptors. They have important clinical uses, but the treatment of is one of them. M agonists the ciliary muscle for better in the eye, to pressure.

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    ACh
    both
    muscarinic
    few
    glaucoma
    constrict
    drainage
    reduce

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Frage 6 von 7

1

Muscarinic antagonists are drugs and antagonists. All muscarinic antagonists show similar effects. CNS effects, and seen especially in children, include restlessness, agitation, hyperactivity, and hyperthermia (from no ).

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    parasympatholytic
    competitive
    peripheral
    excitatory
    sweating

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Frage 7 von 7

1

Cholinesterase inhibitors inhibit from degrading and recycling , and therefore increase ACh, enhancing cholinergic . They inhibit acetylcholinesterase (AChE) and plasma/butylcholinesterases about equally.
Anticholinergic toxidrome (unwanted at therapeutic dose) includes mental , mydriasis(pupil causing poor eyesight), flushed skin, dry skin, and dry mucous membranes.

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    cholinesterases
    acetylcholine
    neurotransmission
    side effects
    confusion
    dilation

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