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PHCY310 Quiz am L34.5 CKD and AKI, erstellt von Mer Scott am 16/04/2019.

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L34.5 CKD and AKI

Frage 1 von 7

1

Choose the incorrect statement about Acute Kidney Injury (AKI).

Wähle eine der folgenden:

  • It is an abrupt decrease in kidney function that occurs over a period of 7 days or less

  • It is stimated to occur in approximately 50% of patients admitted to the intensive care unit (ICU)

  • It can predispose you to CKD

  • CKD patients cannot get AKI

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Frage 2 von 7

1

Choose the incorrect statement about chronic kidney disease (CKD)

Wähle eine der folgenden:

  • It is abnormalities in kidney structure or function that persist for >90 days

  • It presents a high economic burden

  • At least as many deaths are attributable to kidney disease as to cancer, diabetes or respiratory diseases

  • Risk factors for AKI and CKD, such as advanced age, diabetes and hypertension, often overlap.

  • AKI and CKD are discrete and separate conditions.

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Frage 3 von 7

1

NZ has higher rates of sepsis, post infectious glomerulonephritis and HUS causing AKI compared with other countries in the developed world.

Wähle eins der folgenden:

  • WAHR
  • FALSCH

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Frage 4 von 7

1

Reduced renal blood flow () initiates AKI. It can be as a result of infection (), medications, disease, or trauma. The medication combination likely to cause AKI is the ‘triple whammy’; concurrent use of an inhibitor or an ARB, with a .
AKI is largely and late diagnosis of injury is common.

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    ischemia
    sepsis
    diuretic and an NSAID
    ACE
    asymptomatic

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Frage 5 von 7

1

Pathogenesis of AKI:
1. Disruptions of the glycocalyx and monolayer in renal tubule
2. Upregulation of molecules
3. Enhanced interactions
4. Formation of
5. Inflammation causing overload, imbalances

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    endothelial
    adhesion
    leukocyte-endothelium
    microthrombi
    fluid
    electrolyte

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Frage 6 von 7

1

CKD Pathogenesis"
1. Nephrons atrophy with time
2. Worsened by genetic & environmental factors –
3. Fewer nephrons cause an increase in size, can’t cope & detach – loss of barrier function and impaired filtration -
4. Inflammation, which leads to fibrosis & formation
5. Leads to

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    hypertrophy
    nephron
    podocytes
    proteinuria
    scar
    ischaemia

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Frage 7 von 7

1

Which of these is not a systemic effect of CKD?

Wähle eine der folgenden:

  • Fluid & electrolyte imbalances

  • Anaemia

  • Mineral bone disorder – bone pain, fractures, deformities

  • Metabolic acidosis – muscle wasting, bone demineralisation

  • Hyperuricaemia – systemic inflammation, neurological changes

  • Pruritis

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