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A compilation of all of the quizzes from lecture on relevant topics for the final. I forgot to write down the quizzes for topics 25 and 26 though so those are missing.

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Lecture quizzes

Frage 1 von 21

1

Which property is not essential for the origin of life?

Wähle eine der folgenden:

  • The need to store information

  • The need to duplicate information

  • The need to change information

  • The need to make proteins

  • The need to convert into favorable reactions

Erklärung

Frage 2 von 21

1

Why is it thought that ribozymes are likely to be a legacy from an ancestral RNA world?

Wähle eine der folgenden:

  • They are more stable than RNAs

  • When they act, they require the presence of protein cofactors

  • They act without the participation of protein cofactors.

  • They can be made spontaneously without a DNA template.

  • They are made by proteins

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Frage 3 von 21

1

What was probably the first carrier of genetic information in primitive organisms?

Wähle eine der folgenden:

  • DNA that could self-replicate

  • Proteins

  • Polypeptides

  • RNA that could self-replicate

  • Lipids

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Frage 4 von 21

1

________ can be used to purify transcription activator proteins

Wähle eine der folgenden:

  • Gel mobility shift assays

  • DNA affinity chromatography

  • Centrifugation

  • DNA footprinting

  • ChIP assays

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Frage 5 von 21

1

Sequence specific DNA binding proteins frequently have a region that binds in the major groove because:

Wähle eine der folgenden:

  • It is smaller

  • It contains sequence specific information

  • The minor groove is not available

  • It is positively charged

  • It is negatively charged

Erklärung

Frage 6 von 21

1

The following secondary structures are known to specifically interact with DNA (select all that apply):

Wähle eine oder mehr der folgenden:

  • Alpha helix

  • Beta sheet

  • Unstructured loops

  • Double helix

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Frage 7 von 21

1

What happens at the lac operon in the absence of glucose and presence of lactose?

Wähle eine der folgenden:

  • No expression

  • Low expression

  • The lac repressor binds the promoter

  • High expression

  • The CAP protein doesn't bind to the promoter

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Frage 8 von 21

1

Multiple binding sites for a repressor is advantageous because:

Wähle eine der folgenden:

  • There are too many repressors in cells

  • DNA must be bent to allow transcription

  • Repressors are only active when bound to many sites at once

  • This increases the effective concentration of the repressor

  • Repressors need multiple binding sites to bind ligands

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Frage 9 von 21

1

An operator is:

Wähle eine der folgenden:

  • A protein

  • A protein binding site

  • The same as a promoter

  • A type of repressor

  • The start site for RNA synthesis

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Frage 10 von 21

1

Mammalian x-chromosome inactivation:

Wähle eine der folgenden:

  • Occurs only in humans

  • Prevents females from being mosaics

  • Is not necessary

  • Is necessary for dosage compensation

  • Only occurs in males

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Frage 11 von 21

1

CpG islands are generally found in

Wähle eine der folgenden:

  • Inactive genes

  • Introns

  • Exons

  • Promoters of constantly active genes

  • Promoters of rarely expressed genes

Erklärung

Frage 12 von 21

1

Deamination of methyl-cytosine:

Wähle eine der folgenden:

  • Does not occur

  • Changes methyl-cytosine to thymine

  • Only occurs in the sequence CG

  • Results in genomic imprinting

  • Occurs only in expressed genes

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Frage 13 von 21

1

Sex determination in drosophila is due to:

Wähle eine der folgenden:

  • Riboswitches

  • Alternative splicing

  • Alternative 3' end cleavage

  • Localization of mRNA

  • Alternative translational initiation

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Frage 14 von 21

1

Mirco RNAs (miRNAs):

Wähle eine der folgenden:

  • Are the same as rRNAs

  • Are not encoded by the genome

  • Are found only in bacteria

  • Are involved in gene repression

  • Are part of ribosomes

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Frage 15 von 21

1

Attenuation involves regulation of:

Wähle eine der folgenden:

  • Translation

  • Replication

  • Recombination

  • Transcription

  • Proteolysis

Erklärung

Frage 16 von 21

1

Ion exchange chromatography separates:

Wähle eine der folgenden:

  • Proteins, based on size

  • Proteins, based on surface charge

  • Proteins, based on source

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Frage 17 von 21

1

FRET is used to study:

Wähle eine der folgenden:

  • Protein structure

  • Protein molecular weight

  • Protein/protein interaction

  • Protein sequence

  • Protein denaturation

Erklärung

Frage 18 von 21

1

SDS is used in protein gels to (select all that apply)...

Wähle eine oder mehr der folgenden:

  • Make glassware clean up easier

  • Help denature proteins

  • To create a uniform mass/charge ratio

  • To reduce disulfide bonds

Erklärung

Frage 19 von 21

1

DNA libraries are used to bank (select all that apply):

Wähle eine oder mehr der folgenden:

  • Genomic DNA

  • RNA

  • cDNA

  • Artificial chromosomes

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Frage 20 von 21

1

Dideoxy nucleotides are used in DNA sequences to:

Wähle eine der folgenden:

  • Denature the DNA

  • Hybridize the DNA

  • Chain terminate the DNA

  • Elongate the DNA

  • Transcribe the DNA

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Frage 21 von 21

1

Hybridization of nucleic acids refers to:

Wähle eine der folgenden:

  • A renaturation technique

  • An electrophoretic technique

  • A cloning technique

  • A forensic technique

  • A purification technique

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