Erin Urbanowicz
Quiz von , erstellt am more than 1 year ago

Quiz am NSF Week 7, erstellt von Erin Urbanowicz am 01/10/2019.

105
1
0
Keine Merkmale angegeben
Erin Urbanowicz
Erstellt von Erin Urbanowicz vor fast 5 Jahre
Schließen

NSF Week 7

Frage 1 von 30

1

Your patient has experienced traumatic events in his past. During which stage of the memory processing of the traumatic event might there be a target for intervention?

Wähle eine der folgenden:

  • consolidation

  • encoding

  • reconsolidation

  • retrieval

Erklärung

Frage 2 von 30

1

A 65 year-old right-handed man was brought to the emergency room by his wife one hour after sudden onset of right upper arm/hand weakness and difficulty talking. His wife reported that he seems to understand what she is saying because he is responding appropriately to her questions. However, she states he is only able to produce a few words (e.g."something...wrong...can't talk...doctor"). A physical exam revealed full visual fields, but weakness of the right arm and the right lower face. Which one of the following types of aphasia does the patient demonstrate?

Wähle eine der folgenden:

  • broca's aphasia

  • Anomic Aphasia

  • Global Aphasia

  • Wernicke's Aphasia

Erklärung

Frage 3 von 30

1

According to the DSM-5, which of the following is a symptom of Autism Spectrum Disorder?

Wähle eine der folgenden:

  • Difficulty with social interaction

  • Outbursts of anger and disruptive behavior

  • severe anxiety

  • intellectual disability

Erklärung

Frage 4 von 30

1

A 19 year old presents to clinic with her mother. She suffered from a traumatic brain injury in a motor vehicle accident when celebrating her 18th birthday. She has had significant problems with school performance and daily functioning. Her mother is concerned about her daughter's cognitive ability since the accident and wants to know if her daughter has an intellectual disability. What additional finding would be required for diagnosis of an intellectual disability?

Wähle eine der folgenden:

  • A score of <80 on IQ testing following the accident

  • Presence of MRI abnormality

  • Rating of a 'severe' impairment on neuropsychological testing in any of the following domains: working memory, attention, or executive skills

  • History of difficulties with cognitive and adaptive skills prior to the accident

Erklärung

Frage 5 von 30

1

A 7 year old child presents to your clinic with his foster parents. They are concerned about his school performance and wonder if he may have ADHD. On exam, you note that he is small for his age with a head circumference <5%, has a thin upper lip with flat philtrum, and is very hyperactive (see image). His language skills are on par with those of a 4 year old. Based on this constellation of symptoms, you believe this can be attributed to the most common teratogenic cause of intellectual disability. What prenatal exposure do you suspect?

Wähle eine der folgenden:

  • cigarette smoke

  • alcohol

  • methamphetamines

  • valproic acid

Erklärung

Frage 6 von 30

1

Which thalamic nucleus communicates with other thalamic nuclei and also prevents overstimulation of cortex via GABAergic cortical relays?

Wähle eine der folgenden:

  • Pulvinar

  • Reticular

  • Intralaminar

  • Anterior

Erklärung

Frage 7 von 30

1

Which of the following functions does the pineal body regulate?

Wähle eine der folgenden:

  • Circadian rhythms through the release of melatonin

  • Food intake through the release of leptin

  • Water intake by measuring blood osmolality

  • "Fight or Flight" response through the release of Corticotropin Releasing Hormone

Erklärung

Frage 8 von 30

1

Thalamic pain syndrome (Dejerine-Roussy syndrome) results from a lesion of which thalamic nucleus?

Wähle eine der folgenden:

  • Mediodorsal

  • Pulvinar

  • ventral posterior

  • reticular

Erklärung

Frage 9 von 30

1

Which of the following hypothalamic nuclei are associated with the Papez circuit and memory?

Wähle eine der folgenden:

  • paraventricular nuclei

  • mammillary bodies

  • supraoptic nuclei

  • preoptic nuclei

Erklärung

Frage 10 von 30

1

Orexin, a neuropeptide responsible for wakefulness, arousal, and increased appetite, is released by which hypothalamic nucleus/nuclei?

Wähle eine der folgenden:

  • Ventromedial nuclei

  • mammillary body

  • arcuate nucleus

  • lateral nuclei

Erklärung

Frage 11 von 30

1

On the SLUMS, a patient's memory is tested by determining if a list of 5 words can be registered immediately and recalled again in 5 minutes. What type of memory is being tested with 5 minute recall?

Wähle eine der folgenden:

  • Working

  • Sensory

  • Declarative

  • Implicit

Erklärung

Frage 12 von 30

1

A 45 year old man has had a stroke in his dominant hemisphere. On mental status evaluation, you determine that he constructs sentences with articles and prepositions, with average sentence length of 7-8 words. The sentences have normal intonation and he does not make frequent pauses in his speech. He frequently answers 'yes' to open-ended questions. You have difficulty understanding the content of his responses, despite normal articulation. Which area is most likely affected by his stroke?

Wähle eine der folgenden:

  • Parahippocampal gyrus

  • Superior parietal lobe

  • Posterior superior temporal gyrus

  • cingulate gyrus

Erklärung

Frage 13 von 30

1

Which nucleus is involved in memory formation, providing cholinergic input to the hippocampus?

Wähle eine der folgenden:

  • Raphne nucleus

  • Locus Ceruleus

  • Nucleus basalis of Meynert

  • Nucleus Accumbens

Erklärung

Frage 14 von 30

1

A 33 year old man has 5 days of progressively worsening mental status with fever. He has a first-time seizure in the emergency room. An MRI brain shows hemorrhagic lesions in the bilateral temporal lobes. Based on the most likely diagnosis, what next steps do you take?

Wähle eine der folgenden:

  • Send CSF culture, give ceftriaxone IV

  • Send CSF culture, give oral acyclovir

  • CSF PCR, no available treatments

  • CSF PCR, give IV acyclovir

Erklärung

Frage 15 von 30

1

A 19 year old man has new onset of altered mental status, fever, and new-onset seizures. His MRI brain shows temporal lobe cerebritis. A lumbar puncture shows normal glucose and protein, but a mild pleiocytosis (18 white blood cells) with lymphocytic predominance (92% lymphocytes). These findings suggests that he has which of the following?

Wähle eine der folgenden:

  • Enterovirus

  • West Nile Virus

  • Neisseria Meningtidis

  • Bartonella Henselae

Erklärung

Frage 16 von 30

1

A general pediatrician screens an 18 month old girl at a well-child visit and finds a lack of joint attention by history and examination. She refers her on for a formal diagnostic evaluation at a development clinic with a multidisciplinary autism spectrum disorders team. On her exam, which of the following suggests an absence of joint attention?

Wähle eine der folgenden:

  • She became overly fixated on one toy and spent the rest of the appointment spinning its wheels

  • She does not follow instructions when you ask her to run down the hallway

  • She will not simultaneously regard a toy to which her mother and doctor are both pointing

  • She repetitively licks the screen of her mother's tablet

Erklärung

Frage 17 von 30

1

In the Papez circuit, which brain structure receives input from various cortical areas and is the primary source of input to the hippocampus?

Wähle eine der folgenden:

  • Subiculum

  • Entorhinal cortex

  • Fornix

  • Cingulum

Erklärung

Frage 18 von 30

1

Delirium can be distinguished from depression, dementia, and schizophrenia based on the mental status exam. Which of the following symptoms are characteristic of delirium, and not typical of depression, dementia, or schizophrenia?

Wähle eine der folgenden:

  • Delusions and hallucinations

  • Tearfulness and other mood changes

  • acute onset with fluctuating symptoms

  • Impaired short-term memory

Erklärung

Frage 19 von 30

1

Iatrogenic causes of delirium often include medications. Which of the following medications is likely to cause and/or worsen delirium in hospital patients?

Wähle eine der folgenden:

  • Haloperidol (antipsych)

  • Lorazepam (benzo)

  • clonidine (alpha-2 agonist)

  • acetaminophen

Erklärung

Frage 20 von 30

1

The anatomic distribution of which abnormality in the brain is most closely correlated with the clinical progression of Alzheimer's disease?

Wähle eine der folgenden:

  • Plaques composed of oxidized lipids

  • Neurofibrillary tangles composed of tau

  • Lewy bodies composed of alpha synuclein

  • Prion plaques composed of prion protein

Erklärung

Frage 21 von 30

1

What is the name of the extracellular protein aggregate that is a marker of Alzheimer's disease?

Wähle eine der folgenden:

  • Beta Amyloid

  • Neurofibrillary tangle

  • Alpha Synuclein

  • Prion protein

Erklärung

Frage 22 von 30

1

REM sleep behavior disorder is a core feature of which dementia?

Wähle eine der folgenden:

  • Alzheimer Disease

  • Frontotemporal dementia

  • Lewy body dementia

  • Vascular Dementia

Erklärung

Frage 23 von 30

1

What MRI finding would you most likely observe in a patient with moderate to severe Alzheimer's disease?

Wähle eine der folgenden:

  • Abnormal T2 signal w/in the hippocampus

  • Abnormal T2 signal w/in the brainstem

  • Frontal lobe atrophy

  • Bilateral hippocampal atrophy

Erklärung

Frage 24 von 30

1

A 57-year old lawyer presents with a 1-2 year history of increased impulsivity and disinhibition, leading to the recent loss of his job. His wife describes him as having a tendency to become fixated on one idea without being able to let it go (over the same time period). During the exam, he is extremely jovial and intermittently makes inappropriate comments. Lab workup is normal. What type of neurocognitive disorder is most likely?

Wähle eine der folgenden:

  • Alzheimer's Dementia

  • Lewy Body Dementia

  • Mild Cognitive impairment

  • Frontotemporal dementia

Erklärung

Frage 25 von 30

1

What is the most common type of Creutzfeldt-Jakob disease (CJD)?

Wähle eine der folgenden:

  • Sporadic

  • Iatrogenic

  • Variant

  • Familial

Erklärung

Frage 26 von 30

1

What is the major output tract of the amygdala?

Wähle eine der folgenden:

  • Stria terminalis

  • Fornix

  • Cingulum

  • Medial forebrain bundle

Erklärung

Frage 27 von 30

1

An elderly patient dies from aspiration pneumonia, after a prolonged cognitive decline over several years, characterized mostly by memory loss. There was not significant motor dysfunction. Neuropathological examination of the brain and spinal cord is most likely to reveal which of the following?

Wähle eine der folgenden:

  • Alpha-synuclein positive Lewy bodies in the cortex and midbrain

  • Tau-positive inclusions in the anterior horn cells of the spinal cord

  • Amyloid-beta and Tau positive plaques throughout the cortex

  • Amyloid-beta deposits in vessel walls only

Erklärung

Frage 28 von 30

1

An adult patient dies after approximately two years of progressive muscle weakness, eventually requiring ventilator support. Early symptoms included hyperreflexia and spasticity. Cognitive function was intact, and no significant cortical atrophy was seen on gross examination. Neuropathological examination of the brain and spinal cord is most likely to reveal which of the following?

Wähle eine der folgenden:

  • Alpha-synuclein positive Lewy bodies in the cortex and midbrain

  • Tau-positive inclusions in the anterior horn cells of the spinal cord

  • Amyloid-beta and Tau positive plaques throughout the cortex

  • Amyloid-beta deposits in vessel walls only

Erklärung

Frage 29 von 30

1

Which of the following is required to make a diagnosis of ADHD?

Wähle eine der folgenden:

  • Family history of ADHD

  • Inattention

  • Hyperactivity

  • Age of onset in childhood

Erklärung

Frage 30 von 30

1

Which of the following is a common dose dependent side effect of first line medications used to treat ADHD?

Wähle eine der folgenden:

  • Polyuria

  • Elevated blood pressure

  • Blurry vision

  • diarrhea

Erklärung