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PHCY320 (Oncology) Quiz am ON3 Aseptics/Chemo Hazards, erstellt von Mer Scott am 05/10/2019.

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ON3 Aseptics/Chemo Hazards

Frage 1 von 11

1

Wähle von der Dropdown-Liste, um den Text zu vervollständigen.

( Sterile, Aseptic ) means free from all microbiological contaminants i.e. living organisms, particles, and pyrogens.
( Aseptic, Sterile ) means produced from sterile components in a sterile environment – however it does NOT guarantee sterility.
Pharmacists generally work in ( aseptic, sterile ) conditions with ( sterile, aseptic ) starting materials to prepare aseptic products.

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Frage 2 von 11

1

Contamination/L
• Viable (): Bacteria, fungi, and viruses.
Administration of viable material could result in fever; infection; septicemia; multi-organ failure; death.
• Non-viable: particulate matter e.g. plastic or rubber material, glass shards, and chemical precipitates.
Non-viable material may vessels e.g. if >12 μm they may become trapped in the lungs leading to respiratory failure and death.

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    live
    Undissolved
    occlude

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Frage 3 von 11

1

What is laminar flow air?

Wähle eine der folgenden:

  • Smooth, steady, constant flow.

  • Turbulent, rapid flow.

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Frage 4 von 11

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Clean air eg a -free working environment, is made by drawing laminar air into the , through the system.
• HEPA-filtered air ( filter)
• High airflow, filtered and replenished

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    particle
    cabinet
    filtration
    high-efficiency particulate air
    constantly

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Frage 5 von 11

1

In horizontal air flow the product is protected but the operator is not. Vertical air flow protects both the product and operator.

Wähle eins der folgenden:

  • WAHR
  • FALSCH

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Frage 6 von 11

1

Choose the incorrect statement.

Wähle eine der folgenden:

  • Critical points on equipment should never be exposed to clean air

  • Starting materials are removed from their outer wrapping before entering the clean room – minimises the generation of particulate matter in the clean room.

  • Needles are mostly used for one manipulation only, either withdrawing from a container or transferring into a container.

  • After spraying with 70% ethanol, allow time for the ethanol to evaporate.

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Frage 7 von 11

1

Critical Points on a Syringe:
Any ‘connection’ point:
• Tip of
• Hub of needle & tip of filter
• Hub of filter & tip of syringe
• Syringe

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    needle
    plunger

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Frage 8 von 11

1

Pharmacist involvement:
of cytotoxics
– Preserve safety of self and product
of cytotoxics
– Calculations
– Precise and accurate must be given
• Advising nursing staff how to administer cytotoxic products
• Providing medicines information and advice

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    Preparation
    Dispensing
    instructions

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Frage 9 von 11

1

Administration of any IV medicine carries a risk of extravasation ( from vein into tissue). This is NOT a side effect. Regarding extravasation:
• Common term is “tissued”
• Can result in pain, swelling, and at the injection site
• If the drug is a (causes blistering) it can cause severe tissue damage and necrosis (and can continue for months after injury)
• Oncology nurses take care to ensure extravasation does not occur
• Patients must be educated to report any discomfort and/or pain administration

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    leakage
    damage
    vesicant
    extreme
    during

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Frage 10 von 11

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Central lines (catheters for administration)
• Via jugular or subclavian with tip at superior vena cava (e.g. Hickman port, double/single lumen).
• PICC (peripherally-inserted central catheter), starts at the and is placed centrally

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    vein
    arm

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Frage 11 von 11

1

Cytotoxic drugs are potentially lethal especially if delivered via the route.
• Dose varies between intramuscular (IM), intravenous (IV), and intrathecal (IT – the space that holds the ) routes
• The formulation may vary between routes
eg is often given intrathecally, but is fatal by this route

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    wrong
    greatly
    CSF
    vincristine
    Methotrexate

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