Some LAIs:
1. Aripiprazole Maintena
Duration of action and time to steady state = ❌ weeks. Tmax = ❌ with continuous therapy. Half-life = ❌ days (300mg) or ❌ days (400 mg).
2. Olanzapine palmoate
Given every ❌. Suspension in solution injected into ❌ muscle. Duration of action = ❌ weeks. Tmax = ❌. T ½ = ❌. Steady state = 12 weeks.
3. Paliperidone palmitate
Major active metabolite of ❌, acts at D2 and 5-HT2A receptors. Duration of action ~❌ weeks. Tmax median ❌. Cmax is 28% higher with ❌ versus gluteal injection. ❌ dosing. Formulations mean no ❌ test needed first, but first dose is followed by the 2nd at day 8.
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7-24 days or 5-7 days
7-24 days or 5-7 days