Emily Doyle
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Pathophysiology: The Biologic Basis for Disease in Adults and Children 8th Edition

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Emily Doyle
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Chapter 22: Alterations of Hormonal Regulation

Frage 1 von 40

1

The effects of the syndrome of inappropriate antidiuretic hormone (SIADH) secretion include
which solute?

Wähle eine der folgenden:

  • Sodium and water retention

  • Sodium retention and water loss

  • c. Sodium dilution and water retention

  • Sodium dilution and water loss

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Frage 2 von 40

1

Which patient would the healthcare professional assess for elevated levels of antidiuretic hormone (ADH) secretion?

Wähle eine der folgenden:

  • Being treated for small cell carcinoma of the stomach

  • Taking high dose acetaminophen (Tylenol) for arthritis

  • Had a hip replacement operation 14 days ago

  • Has long-standing kidney disease from diabetes

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Frage 3 von 40

1

Which laboratory value would the nurse expect to find if a person is experiencing syndrome
of inappropriate antidiuretic hormone (SIADH)?

Wähle eine der folgenden:

  • Hypernatremia and urine hypoosmolality

  • . Serum potassium (K+) level of 5 mEq/L and urine hyperosmolality compared to
    serum

  • Serum sodium (Na+) level of 120 mEq/L and serum osmolality 260 mOsm/kg

  • Serum potassium (K+) of 2.8 mEq/L and serum hyperosmolality

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Frage 4 von 40

1

What is diabetes insipidus a result of?

Wähle eine der folgenden:

  • Antidiuretic hormone hyposecretion

  • Antidiuretic hormone hypersecretion

  • Insulin hyposecretion

  • Insulin hypersecretion

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Frage 5 von 40

1

A patient who is diagnosed with a closed head injury has a urine output of 6 to 8 L/day.
Electrolytes are within normal limits, but the antidiuretic hormone (ADH) level is low.
Although the patient has had no intake for 4 hours, no change in the polyuria level has occurred. What treatment or diagnostic testing does the healthcare professional prepare the
patient for?

Wähle eine der folgenden:

  • Administration of desmopressin

  • Serum copeptin testing

  • Insulin administration

  • Renal angiogram

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Frage 6 von 40

1

A patient is having a water deprivation test. The patient’s initial weight was 220 pounds (100 kg). The next weight is 209 pounds (95 kg). What action by the healthcare professional is
most appropriate?

Wähle eine der folgenden:

  • Stop the water deprivation test.

  • Administer salt tablets.

  • Continue with the test as planned.

  • Take the patient’s blood glucose.

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Frage 7 von 40

1

A healthcare professional is caring for four patients. Which patient does the professional assess for neurogenic diabetes insipidus (DI)?

Wähle eine der folgenden:

  • Anterior pituitary tumor

  • Thalamus hypofunction

  • Posterior pituitary trauma

  • Renal tubule disease

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Frage 8 von 40

1

Which form of diabetic insipidus (DI) will result if the target cells for antidiuretic hormone (ADH) in the renal collecting tubules demonstrate insensitivity?

Wähle eine der folgenden:

  • Neurogenic

  • Nephrogenic

  • Psychogenic

  • Ischemic

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Frage 9 von 40

1

Which laboratory value is consistent with diabetes insipidus (DI)?

Wähle eine der folgenden:

  • Low urine-specific gravity

  • Low serum sodium

  • Low urine protein

  • High serum total protein

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Frage 10 von 40

1

A patient has nephrogenic diabetes insipidus (DI). What treatment does the healthcare professional anticipate for this patient?

Wähle eine der folgenden:

  • Exogenous ADH replacement

  • Intranasal desmopressin

  • Water and sodium restriction

  • Loop diuretic administration

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Frage 11 von 40

1

Which condition may result from pressure exerted by a pituitary tumor?

Wähle eine der folgenden:

  • Hypothyroidism

  • Hypercortisolism

  • Diabetes insipidus

  • Insulin hyposecretion

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Frage 12 von 40

1

A healthcare professional reads a chart that notes the patient has panhypopituitarism. What does the professional understand that term to mean?

Wähle eine der folgenden:

  • The patient has a lack of all hormones associated with the anterior pituitary gland.

  • The patient has a lack of all hormones associated with the lateral pituitary gland.

  • The patient has total adrenocorticoptropic hormone deficiency.

  • The patient has a dysfunction of the posterior pituitary gland due to a tumor.

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Frage 13 von 40

1

Visual disturbances are a result of a pituitary adenoma because of what?

Wähle eine der folgenden:

  • Liberation of anterior pituitary hormones into the optic chiasm

  • Pituitary hormones clouding the lens of the eyes

  • Pressure of the tumor on the optic chiasm

  • Pressure of the tumor on the optic and oculomotor cranial nerves

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Frage 14 von 40

1

A patient has an enlarged tongue, body odor, rough skin, and coarse hair. Which laboratory result does the healthcare professional associate with this presentation?

Wähle eine der folgenden:

  • Decreased blood glucose

  • Increased growth hormone

  • Decreased ACTH

  • Increased TSH

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Frage 15 von 40

1

A patient has acromegaly. What assessment by the healthcare professional would be most important?

Wähle eine der folgenden:

  • Skin condition

  • Sleep patterns

  • Bowel function

  • Range of motion

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Frage 16 von 40

1

Why does giantism occur only in children and adolescents?

Wähle eine der folgenden:

  • Their growth hormones are still diminished.

  • Their epiphyseal plates have not yet closed.

  • Their skeletal muscles are not yet fully developed.

  • Their metabolic rates are higher than in adulthood.

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Frage 17 von 40

1

A patient chart notes the patient has amenorrhea, galactorrhea, hirsutism, and osteoporosis.
What diagnostic test would the healthcare professional prepare the patient for?

Wähle eine der folgenden:

  • Water deprivation test

  • Hemoglobin A1C

  • CT scan of the head

  • Ovarian biopsy

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Frage 18 von 40

1

What does Graves’ disease develop from?

Wähle eine der folgenden:

  • A viral infection of the thyroid gland that causes overproduction of thyroid hormone

  • An autoimmune process during which lymphocytes and fibrous tissue replace
    thyroid tissue

  • A thyroid-stimulating immunoglobulin that causes overproduction of thyroid hormones

  • An ingestion of goitrogens that inhibits the synthesis of the thyroid hormones, causing a goiter

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Frage 19 von 40

1

Which patient would the healthcare professional assess for other signs of thyrotoxic crisis?

Wähle eine der folgenden:

  • Constipation with gastric distention

  • Bradycardia and bradypnea

  • Hyperthermia and tachycardia

  • Constipation and lethargy

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Frage 20 von 40

1

Which pathologic changes are associated with Graves’ disease?

Wähle eine der folgenden:

  • High levels of circulating thyroid-stimulating immunoglobulins

  • Diminished levels of thyrotropin-releasing hormone

  • High levels of thyroid-stimulating hormone

  • Diminished levels of thyroid-binding globulin

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Frage 21 von 40

1

A healthcare professional is palpating the neck of a person diagnosed with Graves’ disease.
What finding would the professional associate with this disorder?

Wähle eine der folgenden:

  • Parathyroids left of midline

  • Thyroid small with discrete nodules

  • Parathyroids normal in size

  • Thyroid diffusely enlarged

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Frage 22 von 40

1

A person has hypothyroidism. What chemical does the healthcare professional advise the
person to include in the diet?

Wähle eine der folgenden:

  • Iron

  • Iodine

  • Zinc

  • Magnesium

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Frage 23 von 40

1

A patient has a suspected thyroid carcinoma. What diagnostic test does the healthcare
professional prepare the patient for?

Wähle eine der folgenden:

  • Measurement of serum thyroid levels

  • Radioisotope scanning

  • Ultrasonography

  • Fine-needle aspiration biopsy

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Frage 24 von 40

1

Renal failure is the most common cause of which type of hyperparathyroidism?

Wähle eine der folgenden:

  • Primary

  • Secondary

  • Exogenous

  • Inflammatory

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Frage 25 von 40

1

A patient had a thyroidectomy and now reports tingling around the mouth and has a positive Chvostek sign. What laboratory finding would be most helpful to the healthcare professional?

Wähle eine der folgenden:

  • TSH and T4

  • Serum sodium

  • Serum calcium

  • Urine osmolality

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Frage 26 von 40

1

A patient diagnosed with diabetic ketoacidosis (DKA) has the following laboratory values:
arterial pH 7.20; serum glucose 500 mg/dL; positive urine glucose and ketones; serum
potassium (K+) 2 mEq/L; serum sodium (Na+) 130 mEq/L. The patient reports that he has
been sick with the “flu” for 1 week. What relationship do these values have to his insulin
deficiency?

Wähle eine der folgenden:

  • Increased glucose use causes the shift of fluid from the intravascular to the intracellular space.

  • Decreased glucose use causes fatty acid use, ketogenesis, metabolic acidosis, and osmotic diuresis.

  • Increased glucose and fatty acids stimulate renal diuresis, electrolyte loss, and metabolic alkalosis.

  • Decreased glucose use results in protein catabolism, tissue wasting, respiratory acidosis, and electrolyte loss

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Frage 27 von 40

1

Why does polyuria occur with diabetes mellitus?

Wähle eine der folgenden:

  • Formation of ketones

  • Chronic insulin resistance

  • Elevation in serum glucose

  • Increase in antidiuretic hormone

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Frage 28 von 40

1

A student asks the professor to differentiate Type 2 diabetes mellitus from Type 1. The
professors’ response would be that Type 2 is best described as what?

Wähle eine der folgenden:

  • Resistance to insulin by insulin-sensitive tissues

  • Need for lifelong insulin injections

  • Increase of glucagon secretion from beta cells of the pancreas

  • Presence of insulin autoantibodies that destroy beta cells in the pancreas

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Frage 29 von 40

1

A person diagnosed with type 1 diabetes experienced an episode of hunger, lightheadedness, tachycardia, pallor, headache, and confusion. The healthcare professional teaches the person that what is the most probable cause of these symptoms?

Wähle eine der folgenden:

  • Hyperglycemia caused by incorrect insulin administration

  • Dawn phenomenon from eating a snack before bedtime

  • Hypoglycemia caused by increased exercise

  • Somogyi effect from insulin sensitivity

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Frage 30 von 40

1

Which serum glucose level would indicate hypoglycemia in a newborn?

Wähle eine der folgenden:

  • 28 mg/dL

  • 40 mg/dL

  • 60 mg/dL

  • 80 mg/dL

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Frage 31 von 40

1

When comparing the clinical manifestations of both diabetic ketoacidosis (DKA) and
hyperglycemic hyperosmolar nonketotic syndrome (HHNKS), which condition is associated with only DKA?

Wähle eine der folgenden:

  • Fluid loss

  • Weight loss

  • Increased serum glucose

  • Kussmaul respirations

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Frage 32 von 40

1

Hypoglycemia, followed by rebound hyperglycemia, is observed in those with what?

Wähle eine der folgenden:

  • The Somogyi effect

  • The dawn phenomenon

  • Diabetic ketoacidosis

  • Hyperosmolar hyperglycemic nonketotic syndrome

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Frage 33 von 40

1

A patient has diabetes mellitus. A recent urinalysis showed increased amounts of protein. What therapy does the healthcare provider educate the patient that is specific to this disorder?

Wähle eine der folgenden:

  • More frequent blood glucose monitoring

  • Moderate dietary sodium restriction

  • Treatment with an ACE inhibitor

  • Home blood pressure monitoring

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Frage 34 von 40

1

Which classification of oral hypoglycemic drugs decreases hepatic glucose production and
increases insulin sensitivity and peripheral glucose uptake?

Wähle eine der folgenden:

  • Biguanide (metformin)

  • Sulfonylureas (glyburide)

  • Meglitinides (glinides)

  • α-Glycosidase inhibitor (miglitol)

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Frage 35 von 40

1

What causes the microvascular complications in patients with diabetes mellitus?

Wähle eine der folgenden:

  • The capillaries contain plaques of lipids that obstruct blood flow.

  • Pressure in capillaries increases as a result of the elevated glucose attracting water.

  • The capillary basement membranes thicken, and cell hyperplasia develops.

  • Fibrous plaques form from the proliferation of subendothelial smooth muscle of arteries.

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Frage 36 von 40

1

A healthcare professional advises a person with diabetes mellitus to have an annual eye exam.
When the person asks why this is necessary, the professional states that retinopathy develops in patients with diabetes mellitus because of what reason?

Wähle eine der folgenden:

  • Plaques of lipids develop in the retinal vessels.

  • Pressure in the retinal vessels increase as a result of increased osmotic pressure.

  • Ketones cause microaneurysms in the retinal vessels.

  • Retinal ischemia and red blood cell aggregation occur.

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Frage 37 von 40

1

A person has acne, easy bruising, thin extremities, and truncal obesity. The healthcare professional assesses the person for which of these?

Wähle eine der folgenden:

  • Previous thyroid surgery

  • Urine osmolality

  • Serum electrolytes

  • Use of glucocorticoids

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Frage 38 von 40

1

A person may experience which complications as a result of a reduction in parathyroid hormone (PTH)? (Select all that apply.)

Wähle eine oder mehr der folgenden:

  • Muscle spasms

  • Tonic-clonic seizures

  • Laryngeal spasms

  • Hyporeflexia

  • Asphyxiation

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Frage 39 von 40

1

A chronic complication of diabetes mellitus is likely to result in microvascular complications
in which areas? (Select all that apply.)

Wähle eine oder mehr der folgenden:

  • Eyes

  • Coronary arteries

  • Renal system

  • Peripheral vascular system

  • Nerves

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Frage 40 von 40

1

What are clinical manifestations of hypothyroidism? (Select all that apply.)

Wähle eine oder mehr der folgenden:

  • Intolerance to heat

  • Restlessness

  • Constipation

  • Bradycardia

  • Lethargy

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