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Randomized Controlled Trials (RCTs)
Randomization
Observational Studies
Prospective observational studies
Retrospective observational studies
Advantages of RCTs
Disadvantages of RCTs
Advantages of Observational Studies
Disadvantages of Observational Studies (1)
Disadvantages of Observational Studies (2)
Disadvantages of Observational Studies (3)
Advantages of Prospective randomized, controlled trial
Disadvantages of Prospective randomized, controlled trial
Advantages of Retrospective database
Disadvantages of Retrospective database
Examples of types of retrospective databases in PharmacoEconomics
Sensitivity analysis
selection biases
channeling bias
Electronic Medical Records [EMR]
National Health Surveys [NHS]
The Medical Expenditure Panel Survey (MEPS) [1]
The Medical Expenditure Panel Survey (MEPS) [2]
Insurance and Claims Records [ICR]
Advantages of Insurance and Claims Records
Disadvantages of Insurance and Claims Records
5 issues to consider when Critiquing Retrospective Database Studies
what to look for in "Clear Explanation of the Database"
what to look for in "Clear Explanation of Patient-Selection Criteria"
what to look for in " Eligibility of Patients"
what to look for in "Clinical or Outcome Measures" (1)
what to look for in "Clinical or Outcome Measures" (2)
what to look for in "Sensitivity Analyses"
