Asthma and COPD Pharmacology

Name one type of Asthma Medication Classification

Name one type of Asthma Medication Classification

Name the three major characteristics of Asthma - pathophysiology

Asthma symptomology

name three main types of inhalation devices

List some advantages for administering drugs via inhalation

How much drugs reaches the lungs with a Metered Dose Inhaler?

Is there more or less efficacy if the a MDI is cold?

List the important steps of MDI technique:

What should you remember to do after using an inhaler and why?

List the difference in the amount of drug that reaches the lungs using a spacer vs. not using a space:

What is a DPI (Dry powder inhaler)?

List the steps involved in use an DPI Turbuhaler:

What is a nebulizer?

what are some of the disadvantages of a Nebulizer?

What are some of the advantages of a Nebulizer?

What is a steroid?

What do Corticosteroids do?

What do Corticosteroids increase?

Will Corticosteroids relieve an acute attack?

What systems do corticosteroids affect?

Inhaled Corticosteroids (ICS)

short term Side effects of ICS

long term side fx of ICS in high doses

ICS in children

Side effects of Oral corticosteroids: short term:

Long term SFX of OCS:

What is Adrenal insufficiency?

Control of Cortisol

Stress and adrenal insufficiency: stress = infection, exercise, surgery

A. Insuff.

Corticosteroid withdrawal:

Other common uses of corticosteroids

Beta 2 agonists:
Inhaled Long acting or short acting
ORAL

Inhaled short acting Beta 2 agonists: SABA

Inhaled long acting Beta 2 agonists: LABA

Combo ICS and LABA

Oral beta 2 agonists

Parental Beta 2 Agonists

Side effects of Parental Beta 2 Agonists

Salbutamol dosing

Beta 2 agonists : SFX

Beta 2 agonists overuse

Leukotriene Receptor Antagonists (LTRAs)

LTRAS

Cromolyn (Sodium Cromoglycate) - LTRA

Cromolyn (Sodium Cromoglycate) route LTRA

Theophylline LTRA

Theophylline LTRA

Theophylline LTRA side effects

Theophylline LTRA drug interactions

Muscarinic Antagonists:

Short acting Muscarinic Antagonists (SAMA) - MDI, Nebulizers

Long acting Muscarinic Antagonisits (LAMA) - DPI

Measuring lung function FEV1

Limitations to FEV1

Measuring Lung Function PEFR

Zone System for self monitoring PEFR

Key principles of Asthma Care

Symbicort as single inhaler therapy

Emergency management of Asthma

Non Pharmacologic options

COPD - Major features

Clinical manifestations Asthma

Acute exacerbations of COPD (AECOPD)

How many AE per year

Goal of COPD therapy

Goal of AE-COPD therapy

Management of COPD

Pharma of COPD

if you have greater or equal to two AE a year what is your pharma?

Role of ICS in COPD

Theophylline in COPD:"

Roflumilast in COPD

SFX of Roflumilast

Management of AECOPD

Pharmacotherapy of AECOPD: Bronchodilators

Pharm AECOPD : corticosteroids

Pharma AECOPD: Antibiotics