List all systemic (oral) corticosteroids
[Hint: MPP]
List all Inhaled corticosteroids
[Hint: BBC - F]
What is the difference concerning the use of systemic (oral) corticosteroid and inhaled corticosteroid?
List all common SABAs (Inhalers for Rescue).
List all common LABAs (Inhalers for maintenance)
List all common Systemic B2 agonists
List the common SAMA
* Short Acting Muscrarinic Antagonist
** Anticholinergics
List the common LAMAs
* Long Acting Muscrarinic Antagonists
** Anticholinergics
List all common CysLT1 Receptor Antagonists
* Leukotriene Modifiers
** ~ Lukasts
List the common 5-Lipoxygenase Inhibitors
*Leukotriene Modifiers
List the common Mast Cells Stabilizers
List the common SELECTIVE PDE4
* Phosphodiesterase inhibitors
List the common NON-SELECTIVE PDE4
* Phosphodiesterase inhibitors
Significant AEs of Corticosteroids are ------ ?
Significant AEs of B2 agonists are ------ ?
[Hint: TTHQ]
Significant AEs of LAMAs
* Long Acting Muscrarinic Antagonists
** Anticholinergics = Ipratropium
Significant AEs of cromolyn (Mast Cell stabilizers) are ------ ?
Why does Ipratropium need to be dosed multiple times a day?
Why does aclidinium dosed BID for COPD?
Why does tioptropium dose once a day for COPD?
Describe the MOA of Montelukast and Zafirlukast?
* Both are Leukotriene modifiers
** Both are CysLT1 receptor antagonists (CRA)
Describe the MOA of Zileuton?
* It is a Leukotriene modifier
** It is a 5-lipoxygenase (5-LOX) inhibitor
Explain the benefits of Theophylline.
* A non-selective PDE inhibitor.
What is the therapeutic range of Theophylline?