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Pharmacology quiz using the Independent and Supplementary prescribing text book.

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Independent and Supplementary Prescribing

Frage 1 von 24

1

Choose the word or phrase from the list below that best completes this sentence.

Pharmacokinetics can be described as ________________________

Wähle eine der folgenden:

  • how the drug elicits it's effect in the body.

  • how the body handles a drug.

  • the composition of a drug.

  • the way in which a drug should be stored.

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Frage 2 von 24

1

Choose the word or phrase from the list below that best completes this sentence.

Drugs may act locally or systemically. Systemically means that the drug must enter ___________________ in order to be delivered to its site of action.

Wähle eine der folgenden:

  • the brain

  • the circulation

  • the lymph nodes

  • the heart

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Frage 3 von 24

1

Which equation can you use to calculate the amount of a drug that reaches the systemic circulation?

Wähle eine der folgenden:

  • F x dose

  • F/dose

  • F - dose

  • F + (2 x dose)

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Frage 4 von 24

1

Choose the word or phrase from the list below that best completes this sentence.

Drugs administered as an IV injection have a bioavailability of _________.

Wähle eine der folgenden:

  • 100

  • 10

  • 1.0

  • 0.1

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Frage 5 von 24

1

What words make up the acronym ADME?

Wähle eine oder mehr der folgenden:

  • Administration

  • Absorption

  • Distribution

  • Dissolving

  • Making

  • Metabolism

  • Exit

  • Excretion

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Frage 6 von 24

1

Choose the word or phrase from the list below that best completes this sentence.

Generally in absorption, drugs move from an area of high concentration to a low concentration via ______________

Wähle eine der folgenden:

  • osmosis.

  • active transport.

  • passive diffusion.

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Frage 7 von 24

1

Choose the word or phrase from the list below that best completes this sentence.

When drugs are being absorbed from an area of their low concentration to a higher concentration, they move by _____________

Wähle eine der folgenden:

  • active transport.

  • osmosis.

  • passive diffusion.

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Frage 8 von 24

1

Choose the word or phrase from the list below that best completes this sentence.

Cell membranes are composed of a double layer of ____________________

Wähle eine der folgenden:

  • proteins.

  • sugars.

  • phospholipids.

  • ions.

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Frage 9 von 24

1

Water soluble drugs pass cell membranes easier than lipid soluble drugs.

Wähle eins der folgenden:

  • WAHR
  • FALSCH

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Frage 10 von 24

1

Choose the word or phrase from the list below that best completes this sentence.

The more _______________ a drug, the easier it is for the drug to be absorbed from the small intestine into the circulation.

Wähle eine der folgenden:

  • lipid soluble

  • water soluble

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Frage 11 von 24

1

Un-ionised drugs are lipid soluble.

What does un-ionised mean?

Wähle eine der folgenden:

  • The drug carries no charge.

  • The drug is negatively charged.

  • The drug is positively charged.

  • The molecule contains two opposing charges.

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Frage 12 von 24

1

Choose the word or phrase from the list below that best completes this sentence.

The small intestine has a large surface area due to it's large number of __________.

Wähle eine der folgenden:

  • villi

  • cillia

  • hairs

  • cells

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Frage 13 von 24

1

Choose the word or phrase from the list below that best completes this sentence.

The larger the surface area for drug absorption, the _______ the absorption.

Wähle eine der folgenden:

  • slower

  • quicker

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Frage 14 von 24

1

Where does most drug absorption take place?

Wähle eine der folgenden:

  • Stomach

  • Small Intestine

  • Large Intestine

  • Colon

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Frage 15 von 24

1

The presence of food after a meal will slow gastric emptying.

Wähle eins der folgenden:

  • WAHR
  • FALSCH

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Frage 16 von 24

1

Sometimes drugs are prescribed to be taken with food. Why might this be?

Wähle eine oder mehr der folgenden:

  • To lessen the side effects of a drug by preventing large concentrations from entering systemic circulation at the same time, ensuring a more gradual absorption due to gastric emptying.

  • To mask the bad taste of a drug that is taken orally.

  • To prevent local side effects, like irritation of the stomach lining, caused by drugs like NSAIDs.

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Frage 17 von 24

1

Choose the word or phrase from the list below that best completes this sentence.

Some drugs are absorbed from the small intestine into the _____________ and are transported directly into the liver.

Wähle eine der folgenden:

  • renal portal vein

  • cranial portal vein

  • hepatic portal vein

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Frage 18 von 24

1

What is the name of the process by which a drug is fully or partially metabolised by the liver, before entering the systemic circulation?

Wähle eine der folgenden:

  • First pass metabolism

  • Liver/drug degradation

  • First past metabolism

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Frage 19 von 24

1

Hypomotility of the GI tract may result in lower concentrations of drug entering the circulation.

Wähle eins der folgenden:

  • WAHR
  • FALSCH

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Frage 20 von 24

1

Blood flow affects absorption.

Wähle eins der folgenden:

  • WAHR
  • FALSCH

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Frage 21 von 24

1

Choose the word or phrase from the list below that best completes this sentence.

A drug must reach it's site of action in ______________, in order to exert it's effect.

Wähle eine der folgenden:

  • an adequate concentration

  • a membrane bound vesicle

  • a salt solution

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Frage 22 von 24

1

Blood flow affects distribution.

Wähle eins der folgenden:

  • WAHR
  • FALSCH

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Frage 23 von 24

1

Blood flow affects distribution. Organs that have high perfusion, e.g. heart, therefore receive drugs slowly.

Wähle eins der folgenden:

  • WAHR
  • FALSCH

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Frage 24 von 24

1

Choose the word or phrase from the list below that best completes this sentence.

Only ________ drug can cross plasma membranes and therefore exert an effect.

Wähle eine der folgenden:

  • free

  • plasma protein bound

  • albumin bound

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