All of the following are correct about Ludwig's Angina EXCEPT:
Fascial inflammation w/ b/l involvement of the submandibular, sublingual, and submental spaces
S/S include dysphagia, odynophagia, difficulty breathing, pain; B/L lower facial edema around the mandible and neck
Caused by anaerobes only
Must tx infection (with penicillin G) and maintain airway. tracheotomy may be necessary
Diarrhea, pneumonia, TB, and Malaria have been primary disease killers in 2012, just like they were in 1900.
CDC estimates there are 90,000-200,000 deaths occur annually d/t Nosocomial infections
Which of the following is not a threat to current antibiotic tx available
MRSA
VRE
E coli resistant to ciprofloxacin
E coli resistant to bactrim
BGM resistant to penicillin
Substances that act against or destroy infections (Fungal/Viral/Bacterial)
Anti-infective agent
Antibacterial Agents
Antibiotics
Antimicrobials
What are substances that destroy or suppress the growth or multiplication of bacteria?
Antibacterial agents
Substances produced by bacteria that can destroy or suppress the growth or multiplication of bacteria or prevent the action of bacteria are which of the following:
Antibacterial
Anti-infective agents
MRSA stands for Methicillin Resistant Staphylococcus Aureus. What group of penicillin abx does Methicillin belong to?
Aminopenicillins
Ureidopenicillins
Caboxypenicillins
Antistaphylococcal
Fred is a 75 y/o man w/ a hx of pneumonia which a culture showed was positive for Klebsiella. Which of the following is the BEST choice of abx for this patient?
Pipericillin
Ampicillin
Vancomycin
Doxycycline
Protein synthesis inhibitors only target 30S and 50S subunits
Plasmid encoded acetyltransferases that inactivate which of the following drugs?
Chloramphenicol
Tetracycline
Streptomycin
Cloxacillin
Which of the following is not a risk factor for pseudomembranous colitis
Antibiotics (clindamycin, cephalosporins, ampicillin, erythromycin)
Elderly
Females w/ GU diseases
Infants
Sulfonamides are a structural analogue of what?
PABA
DHFR
Di
CD-4
Which of the following antifungals should NOT be used for superficial mycoses
Amphotericin B
Nystatin
Terbinafine
Griseofulvin
When should you give Amphotericin B
With all the other drugs, it will help with the absorption
PO first thing in the morning
Before other drugs, after you have given them NSAIDs and antiemetics for possible side effects.
Whenever you damn feel like.
Nystatin is incredibly toxic so you cannot use it for oral thrush.
Amphotericin B causes damage to what component of host cells?
Mitochondria
Cholesterol
Ribosomes
Amino Acids
Which of the following Azole antifungals is a prodrug?
Itraconazole
Fluconazole
Voriconazole
Ketoconazole
Which of the following cannot be applied topically?
Clotrimazole
Miconazole
