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Pharmacology - Bio 528

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Cholinergics and Anticholinergics

Frage 1 von 19

1

ACh is released from the terminal of each of the following neurons EXCEPT:

Wähle eine der folgenden:

  • sympathetic preganglionic neuron innervating the adrenal medulla

  • sympathetic postganglionic neuron innervating the GI tract

  • parasympathetic postganglionic neuron innervating the pupil of the eye

  • motor nerve innervating skeletal muscle

Erklärung

Frage 2 von 19

1

Postsynaptic nicotinic receptors are found at each of the following sites EXCEPT:

Wähle eine der folgenden:

  • adrenal medulla

  • sinoatrial node

  • autonomic ganglia

  • skeletal muscle motor end-plate

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Frage 3 von 19

1

Another name for the sympathetic nervous system outflow is the...

Wähle eine der folgenden:

  • thoracolumbar outflow

  • craniosacral outflow

  • somatic outflow

  • autonomic outflow

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Frage 4 von 19

1

You would MOST AVOID administering which of the following drugs to the patient taking an MAO inhibitor?

Wähle eine der folgenden:

  • meperidine

  • ephedrine

  • halothane

  • propranolol

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Frage 5 von 19

1

Release of neurotransmitter requires the entry of what substance into the nerve terminal?

Wähle eine der folgenden:

  • sodium

  • potassium

  • magnesium

  • calcium

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Frage 6 von 19

1

Which of the following is the correct pairing for sweat glands (division / neurotransmitter)?

Wähle eine der folgenden:

  • sympathetic - norepinephrine

  • sympathetic - acetylcholine

  • parasympathetic - norepinephrine

  • parasympathetic - acetylcholine

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Frage 7 von 19

1

Side effects of cholinesterase inhibitors include each of the following EXCEPT:

Wähle eine der folgenden:

  • bradycardia

  • increased salivation

  • bronchoconstriction

  • mydriasis

Erklärung

Frage 8 von 19

1

You would avoid which agent if the patient w/ glaucoma is being treated with echothiophate?

Wähle eine der folgenden:

  • remifentanyl

  • thiopental

  • mivacurium

  • edrophonium

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Frage 9 von 19

1

A farmer who one hour ago was spraying his crops with organophosphate insecticide complains of abdominal cramps, muscle weakness, and blurred vision. He is wheezing and bradycardic. Treatment of this condition might reasonably include each of the following agents EXCEPT:

Wähle eine der folgenden:

  • physiostigmine

  • atropine

  • diazepam

  • pralidoxime

Erklärung

Frage 10 von 19

1

Nerves that conduct the action potential the fastest are:

Wähle eine der folgenden:

  • myelinated and have small diameter

  • myelinated and have large diameter

  • unmyelinated and have small diameter

  • unmyelinated and have large diameter

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Frage 11 von 19

1

Signs and symptoms of the anticholinergic syndrome include:

Wähle eine der folgenden:

  • excessive salivation

  • bradycardia

  • excessive sweating

  • mania and hallucinations

Erklärung

Frage 12 von 19

1

Which second messenger promotes bronchoconstriction?

Wähle eine der folgenden:

  • cGMP

  • inositol triphosphate (IP3)

  • cAMP

  • calmodulin

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Frage 13 von 19

1

Which of the following agents produces bronchodilation because of its antimuscarinic actions?

Wähle eine der folgenden:

  • sodium nitroprusside

  • terbutaline

  • aminophylline

  • ipratropium

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Frage 14 von 19

1

Which of the following agents produces the greatest increase in HR?

Wähle eine der folgenden:

  • scopolamine

  • glycopyrrolate

  • atropine

  • pilocarpine

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Frage 15 von 19

1

You want to protect the patient from excessive salivation. You also want to PROMOTE sedation. Which drug would be used?

Wähle eine der folgenden:

  • glycopyrrolate

  • atropine

  • scopolamine

Erklärung

Frage 16 von 19

1

You want to protect the patient from excessive salivation. You also want to AVOID sedation. Which drug would be used?

Wähle eine der folgenden:

  • glycopyrrolate

  • atropine

  • scopolamine

Erklärung

Frage 17 von 19

1

Which antisialogogue is LEAST effective at reducing salivation?

Wähle eine der folgenden:

  • glycopyrrolate

  • atropine

  • scopolamine

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Frage 18 von 19

1

A farmer who one hour ago was spraying his crops with organophosphate insecticide complains of abdominal cramps, muscle weakness, and blurred vision. He is wheezing and bradycardic. What is he suffering from?

Wähle eine der folgenden:

  • anticholinergic overdose

  • cholinergic syndrome or cholinergic crisis

  • anticholinergic syndrome

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Frage 19 von 19

1

68-year-old patient was given scopolamine preop and atropine with edrophonium to reverse muscle paralysis at the end of the case. In PACU the patient becomes restless, combative and confused. A rash on the upper body is seen. Tachycardia is also present. What is the condition called?

Wähle eine der folgenden:

  • anticholinergic syndrome

  • cholinergic syndrome

  • anticholinesterase inhibitor

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