Ifeoma Okekearu
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Schizophrenia

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Ifeoma Okekearu
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Neuro Pharmacology - Schizophrenia

Frage 1 von 13

1

What are the criteria for a schizophrenia diagnosis?

Wähle eine der folgenden:

  • Positive Schizophrenic Symptoms

  • Disorganized Speech/ Thoughts

  • Negative Schizophrenic Symptoms

  • Symptoms lasting > 6 months

  • All of the choices are correct

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Frage 2 von 13

1

Most cognitive symptoms in schizophrenia are correlated with dysfunctions of the mesolimbic system.

Wähle eins der folgenden:

  • WAHR
  • FALSCH

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Frage 3 von 13

1

Which of the following are structural abnormalites are found in the brians of schizophrenic patients.

Wähle eine oder mehr der folgenden:

  • Lateral and Third Ventricular Enlargement

  • Volume Increases of the Prefrontal and Oribitofrontal Cortex

  • Abnormalities of the Basal Ganglia

  • Volume Reduction of the Temporal Lobe

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Frage 4 von 13

1

NMDA Glutamate receptor activation will produce "schizophrenia-like" symptoms in healthy adults.

Wähle eins der folgenden:

  • WAHR
  • FALSCH

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Frage 5 von 13

1

Select all of the statements that are prodromal signs/symptoms of schizophrenia.

Wähle eine oder mehr der folgenden:

  • Sudden development of interest in abstract ideas.

  • Decline is occupational and interpersonal functioning.

  • Quiet, passive, introverted personality

  • Delusions and Hallucinations

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Frage 6 von 13

1

Schizophrenia is sa neurodegenerative disorder

Wähle eins der folgenden:

  • WAHR
  • FALSCH

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Frage 7 von 13

1

Architectural changes are often involved in certain regions of the brains of schizophrenic patients. These same regions become vey active during episodes of hallucination. Which regions below would an MRI show activity during a hallucination?

Wähle eine oder mehr der folgenden:

  • Temporal Lobe

  • Prefrontal Cortex

  • Occipital Lobe

  • Parietal Lobe

  • Hippocampus

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Frage 8 von 13

1

Select the statement(s) below that is/are involved in the manifestations of schizophrenic symptoms.

Wähle eine der folgenden:

  • Schizophrenia patients usually have over-activity of the dopamine D2 receptors.

  • 5-HT2A Receptors are involved in the pathogenesis of schizophrenia

  • Blockage of NMDA glutamate mimic all schizophrenic symptoms suggesting schizophrenic patients have a deficiency in these receptors.

  • All of the above

  • None of the above

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Frage 9 von 13

1

NMDA receptors require multiple stimuli to converge in order for them to become activated.

Wähle eins der folgenden:

  • WAHR
  • FALSCH

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Frage 10 von 13

1

Which statement about the glutaminergic hypothesis of schizophrenia is true?

Wähle eine der folgenden:

  • There is hyperactivity of the mesolimbic system and hypoactivity of the mesocortical system.

  • There is hypoactivity of the mesolimbic system and hypoactivity of the mesocortical system.

  • There is hyperactivity of the mesolimbic system and hyper activity of the mesocortical system.

  • There is hypoactivity of the mesolimbic system and hyperactivity of the mesocortical system.

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Frage 11 von 13

1

What effect would blockage of the dopamine D2 receptors in the CTZ have on a patient?

Wähle eine der folgenden:

  • Parkinsonism

  • Tardive Dyskinesia

  • Anti-Emetic

  • Hypothermia

  • None of the above

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Frage 12 von 13

1

Which option below would NOT be a side effect of the use anticholinergics?

Wähle eine oder mehr der folgenden:

  • Nausea

  • Tachycardia

  • Constipation

  • Blurry Vision

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Frage 13 von 13

1

What is the course of action for the treatment of a psychotic patient that develops the rare Neuroleptic Malignant Syndrome

Wähle eine oder mehr der folgenden:

  • Stop Anti-Psychotic drug, IV Dantrolene, IV Normal Saline, & Bromocriptine

  • Increase Anti-Psychotic drug, PO Dantrolene, Heating Pads, Diphenhydramine

  • Stop Antipsychotic, Injected Diazepam, IV Fluids, Inject Bromocriptine

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