Which drugs are β-lactamase inhibitors?

β-lactamase Inhibitors provide the greatest β-lactam antibiotic potentiation against:

β-lactamase inhibitors are active against:

INFO CARD!!! β-lactamase are typically used in combination with other β-lactam antibiotics. What type of effect do they have on certain types of penicillin (amoxicillin, ampicillin, piperacillin, and ticarcillin)?

Clavulanic acid can be paired up with which penicillins?

Ampicillin is paired up with which β-lactamase inhibitor?

Tazobactam is combined with which penicillin?

What do β-lactamase inhibitors do? (Mechanism of Action)

Clavulanic Acid
1. How is it administered?
2. Where is it absorbed and how long does it take?
3. Excretion?
4. CNS penetration?

Sulbactam
1. How is it administered?
2. Where is it absorbed and how long does it take?
3. Excretion?
4. CNS penetration?

Tazolactam
1. How is it administered?
2. Where is it absorbed and how long does it take?

Adverse Effects of a Ticarcillin-Clavulanic Acid combo

Adverse effects of a Amoxicillin-Clavulanic Acid combo

Adverse Effects of a Piperacillin-Tazolactam combo