When the ligand has bound, what moleucle forms?
A homodimer
A heterodimer within the T.K family
A heterotrimer within the T.K family
A homotrimer
What is found in the active site that inhibits activity?
A pseudosubstrate
An activation lip
A hydrophobic core that must be exposed
How do you activate the active site?
Phosphorylation
Acetylation
Methylation
Which residues of tyrosine kinase are modified?
Tyrosine
Serine
Threonine
What domain is required to bind to an activated Tyrosine Kinase?
Sh2
Sh4
SH3
How large is an SH2 domain?
100 residues
50 residues
25 residues
How many pockets are there in SH2?
1
2
3
How does a specific molecule know where to dock on a tyrosine kinase receptor?
The sequence of aa around the modification it binds to
The shape of the protein around the modification it binds to
