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Describe the process of thyroid hormone production:
1. Iodine is actively transported into the via on the basolateral side of the cell (this is called )
2. Iodine diffuses to the luminal side of the cell
3. Iodine is transported into the follicle lumen by , a membrane transporter
4. The follicle cells secrete (containing ~70 amino acids) into the lumen
5. Iodide ions undergo to form via the action of the enzyme
6. of the thyroglobulin molecule:
---Iodine binds to tyrosine amino acids within the thyroglobulin molecule via the action of
---This forms
---This undergoes further iodine binding to form
---MIT/DIT molecules are coupled to each other
7. If two DIT molecules couple together, is formed
8. If one MIT molecule couples with one DIT molecule, is formed