Which of these is not true?
During glycolysis we will have a fragmentation of 6 Carbon atoms into a molecule of 3 Carbon atoms.
Glycolysis takes place in the cytosol.
Glycolysis is divided into two phases and 10 reactions occur.
The final balance of the glycolysis is the creation of 4 molecules of ATP, 2 of NADH and 2 of pyruvate with a single molecule of glucose.
Three reactions are regulated in glycolysis (1º, 3º and 10º)
Glycolysis appears in all the tissues
Triose phosphate isomerase acts in which reaction?
First reaction: Glucose is phosphorylated into Glucose-6-Phosphate.
Sixth reaction: Glyceraldehyde is phosphorylated and oxydated into 1,3-Biphosphoglycerate.
Seventh reaction: 1,3-BPG transfer the phosphate group to a ATP forming 3-Phospoglycerate.
This enzyme does not act in glycolysis.
This enzyme acts in glycolysis but in any reaction here present.
In which reaction a phosphate group is required from an inorganic molecule?
Sixth reaction
Seventh reaction
Eighth reaction
Ninth reaction
Tenth reaction
Which sequence in glycoysis is true?
Glucose -> Glucose 6-Phosphate -> Fructose 6-Phosphate -> Fructose 1,6 biphosphate -> Dihydroxyacetate phosphate -> Glyceraldehyde 3-Phosphate -> 1,3 Biphosphoglycerate -> 3-Phosphoglycerate -> 2-Phosphoglycerate -> Phosphenolpyruvate -> Pyruvate
Glucose -> Glucose 6-Phosphate ->Fructose 1,6 biphosphate -> Fructose 6-Phosphate -> Dihydroxyacetate phosphate -> Glyceraldehyde 3-Phosphate -> 1,3 Biphosphoglycerate -> 3-Phosphoglycerate -> 2-Phosphoglycerate -> Phosphenolpyruvate -> Pyruvate
Glucose -> Glucose 6-Phosphate -> Fructose 6-Phosphate -> Fructose 1,6 biphosphate -> hydroxyacetate diphosphate -> 1,3 Biphosphoglycerate -> 3-Phosphoglycerate -> 2-Phosphoglycerate -> Phosphenolpyruvate -> Pyruvate
Glucose -> Glucose 6-Phosphate -> Fructose 6-Phosphate -> Fructose 1,6 biphosphate -> Dihydroxyacetate phosphate -> Glyceraldehyde 3-Phosphate -> 3-Phosphoglycerate ->1,3 Biphosphoglycerate -> 2-Phosphoglycerate -> Phosphenolpyruvate -> Pyruvate
Glucose -> Glucose 6-Phosphate -> Fructose 6-Phosphate -> Fructose 1,6 biphosphate -> hydroxyacetate diphosphate -> Glyceraldehyde 3-Phosphate -> 1,3 Biphosphoglycerate -> 3-Phosphoglycerate -> 2-Phosphoglycerate -> Phosphenolpyruvate -> Pyruvate
Which of these is true?
Hexokinases I,II,III have a high specifity and a high affinity.
Glucokinase has a high specifity and a low affinity.
Hexokinases I,II,III are only present in liver.
Glucose-6-phosphate can inhibit glucokinase but can not do anything with hexokinase I,II and III.
In the phosphofructokinase the activators are F26BP, AMP and ATP
What happens if there are high concentrations of ADP and AMP?
The energy charge increases
The energy charge is not affected and ADP and AMP are activators
ATP increases and it is an inhibitor
The energy charge decreases
The citrate concentration increases because it is an activator
Why fructose 2,6-biphosphate is an activator of PFK1?
When PKA phosphorylates the bifunctional enzyme that catalyses the transformation of F6P into F26BP synthesis of glucose is activated and glycolysis in inhibited.
When PKA phosphorylates the bifunctional enzyme that catalyses the transformation of F26BP into F6P synthesis of glucose is activated and glycolysis in activated.
When Adenylate cyclase phosphorylates the bifunctional enzyme that catalyses the transformation of F26BP into F6P synthesis of glucose is activated and glycolysis in inhibited.
When Adenylate cyclase phosphorylates the bifunctional enzyme that catalyses the transformation of F26BP into F6P synthesis of glucose is activated and glycolysis in activated.
When PKA phosphorylates the bifunctional enzyme that catalyses the transformation of F26BP into F6P synthesis of glucose is activated and glycolysis in inhibited.
Which is the correct sequence in a fed state?
Low Glu -> Glucagon -> High AMPc -> +PKA -> BEz is phosphorylated -> Low F26BP -> Glycolysis is blocked
High Glu -> Insulin -> Phosphatases -> Not phosphorylation of BEz -> High F26BP -> Glycolysis is activated
Low Glu -> Insulin -> High AMPc -> +PKA -> BEz is phosphorylated -> Low F26BP -> Glycolysis is blocked
High Glu -> Glucagon -> Phosphatases -> Not phosphorylation of BEz -> High F26BP -> Glycolysis is activated
High Glu -> Insulin -> Phosphatases -> Not phosphorylation of BEz -> Low F26BP -> Glycolysis is activated
In the case of the muscle the regulation of the production of pyruvate kinase depends on epinephrine
What of these we can not do with pyruvate?
Fermentation in absence of O2
Transform pyruvate into ethanol
Produce lactic acid
Act in the Krebs cycle
Transform pyruvate into fructose
