Molecular Chaperones in Bacteria, Yeast & Mammals

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What is the main role of a molecular chaperone?

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Chaperone proteins are permanent parts of the proteins they fold

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Why are chaperone proteins necessary?

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Name the role of the domain highlighted in bacterial trigger factor

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The highlighted domain of Bacterial trigger factor binds to L23 of the ribosome

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The bacterial ribosome and bacterial trigger factor form a complex, so the protein is folded as it comes off the ribosome

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The N-domain of the bacterial trigger factor bind to what subunit of what size ribosome?

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After the protein interacts with the T.F, it may interact with what proteins?

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What percent of proteins can fold unaided after interacting with DNAK/J?

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10-15% of proteins need to use the lidded protein chaperone syastem

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15-18% of proteins need further _ interactions?

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Yeast has no trigger factor

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In yeast, what protein folding complex interacts with the proteins first?

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The RAC complex is made of which proteins?

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SSB is separated from the RAC but also chaperones protein folding

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The NAC is made of A and B homologues

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What is the role of the NAC?

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Human cellss don't possess an NAC

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Humans have an hRAC rather than an RAC

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The human version of the RAC contains which two proteins?

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Name the lidded protein chaperone found in yeast and humans

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Name the circled sets of cytoplasmic folding proteins

Structural Basis for Biological Function (Protein Folding) Quiz am Molecular Chaperones in Bacteria, Yeast & Mammals, erstellt von gina_evans0312 am 20/12/2013.

Molecular Chaperones in Bacteria, Yeast & Mammals

Molecular Chaperones in Bacteria, Yeast & Mammals

What is the main role of a molecular chaperone?

Chaperone proteins are permanent parts of the proteins they fold

Why are chaperone proteins necessary?

Name the role of the domain highlighted in bacterial trigger factor

The highlighted domain of Bacterial trigger factor binds to L23 of the ribosome

The bacterial ribosome and bacterial trigger factor form a complex, so the protein is folded as it comes off the ribosome

The N-domain of the bacterial trigger factor bind to what subunit of what size ribosome?

After the protein interacts with the T.F, it may interact with what proteins?

What percent of proteins can fold unaided after interacting with DNAK/J?

10-15% of proteins need to use the lidded protein chaperone syastem

15-18% of proteins need further _ interactions?

Yeast has no trigger factor

In yeast, what protein folding complex interacts with the proteins first?

The RAC complex is made of which proteins?

SSB is separated from the RAC but also chaperones protein folding

The NAC is made of A and B homologues

What is the role of the NAC?

Human cellss don't possess an NAC

Humans have an hRAC rather than an RAC