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Going viral

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Intro to virology

Intro to virology

Frage 1 von 31

1

The outer surface of the capsid mediates with host cells.

Wähle eine der folgenden:

  • Naked Virus

  • Enveloped Virus

Erklärung

Frage 2 von 31

1

The glycoproteins anchored in the envelope and pointing out mediate contact with the host cells.

Wähle eine der folgenden:

  • Naked Virus

  • Enveloped Virus

Erklärung

Frage 3 von 31

1

Which type of virus is especially Sensitive to lipid solvents (ex. Chloroform, ether) and also to non-ionic detergents.

Wähle eine der folgenden:

  • Naked Viruses

  • Enveloped Viruses

Erklärung

Frage 4 von 31

1

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( Naked, Enveloped ) viruses tend to be more stable to environmental changes than ( Naked, Enveloped ) viruses.

Erklärung

Frage 5 von 31

1

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( Naked, Enveloped ) viruses are usually transmitted via aqueous environment: e.g. various body secretions, blood

Erklärung

Frage 6 von 31

1

Wähle von der Aufklappliste, um den Text zu vervollständigen.

( Naked, Enveloped ) viruses may be transmitted by many routes: e.g. secretions/blood, oral-fecal, skin contact

Erklärung

Frage 7 von 31

1

What viral structure is defined as a lipid bilayer derived from host cell membranes during the process of virus maturation.

Wähle eine der folgenden:

  • Virion

  • Capsid

  • Envelope

  • Nucleocapsid

Erklärung

Frage 8 von 31

1

Which viral structure is defined as a protein shell that surrounds and protects the viral genome?

Wähle eine der folgenden:

  • Virion

  • Capsomer

  • Nucleocapsid

  • Envelope

  • Cell wall

  • Capsid

Erklärung

Frage 9 von 31

1

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( Icosahedral, Helical ) structures approximate spheres.

Erklärung

Frage 10 von 31

1

Icosahedral structures can have which of the following axis/axes of symmetry? (Select all that apply)

Wähle eine oder mehr der folgenden:

  • none. Icosahedral is not symmetrical.

  • two-fold

  • three-fold

  • four-fold

  • five-fold

Erklärung

Frage 11 von 31

1

Helical structures can have which of the following axis/axes of symmetry? (Select all that apply)

Wähle eine oder mehr der folgenden:

  • None. Helical structures are not symmetrical.

  • two-fold

  • three-fold

  • four-fold

  • five-fold

Erklärung

Frage 12 von 31

1

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The Corona family of viruses is classified as
- ( Enveloped, Naked )
-( RNA, DNA ) virus
-with ( helical, icosahedral ) symmetry of the capsid. -It has a ( positive, negative ), ( single-stranded, double stranded ), ( non-segmented, 10-18 segment, 3 Segment, 8 Segment, 2 Segment, 2 copies ) genome.
-It is virion polymerase ( negative, positive ).
-It's genome size is ( 16-21, 22-27, 8, 7.2-8.4, 10, 12, 3.5-9, 12.7, 13-16, 13.5-21, 13.6, 16-20, 10-14 ) kb.

Erklärung

Frage 13 von 31

1

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The Reo family of viruses is classified as
-( Naked, Enveloped )
-( RNA, DNA ) virus
-with ( Icosahedral, Helical ) symmetry of the capsid.
-It has a ( double-stranded, single-stranded ), ( 10-18 segment, non-segmented, 2 copies, 3 segment, 8 segment, 2 segment ) genome.
-It is virion polymerase ( positive., negative. )
-It's genome size is ( 22-27, 8, 7.2-8.4, 10, 12, 3.5-9, 16-21, 12.7, 13-16, 16-20, 10-14 ) total in kb.

Erklärung

Frage 14 von 31

1

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The Calici family of viruses is classified as a:
-( Naked, Enveloped )
-( RNA, DNA ) virus
-with ( Icosahedral, Helical ) symmetry of the capsid.
-It has a ( (+) single-stranded, non-segmented, double-stranded, 10-18 segment, (+) single-stranded, 2 copies, (-) single-stranded, non-segmented, (-) single stranded, 3 segment, (-) single stranded, 8 segment, (-) single-stranded, 2 segment ) genome.
-It is virion polymerase ( negative, positive ).
-It's genome size is ( 8, 22-27, 7.2-8.4, 10, 12, 3.5-9, 16-21, 12.7, 13-16, 13.5-21, 13.6, 16-20, 10-14 ) total in kb.

Erklärung

Frage 15 von 31

1

Wähle von der Dropdown-Liste, um den Text zu vervollständigen.

The Picorna family of viruses is classified as a:
-( Naked RNA, Naked DNA, Enveloped RNA, Enveloped DNA ) virus with ( Icosahedral, Helical ) symmetry of the capsid.
-It has a ( (+) single-stranded, non-segmented, double-stranded, 10-18 segment, (+) single-stranded, 2 copies, (-) single-stranded, non-segmented, (-) single-stranded, 3 segment, (-) single stranded, 8 segment, (-) single stranded, 2 segment ) genome.
-It is virion polymerase ( negative, positive ).
-It's genome size is ( 7.2-8.4, 22-27, 3.5-9, 13.5-21, 8 ) total in kb.

Erklärung

Frage 16 von 31

1

Wähle von der Dropdown-Liste, um den Text zu vervollständigen.

The Flavi family of viruses is classified as a(n):
-( Enveloped RNA, Enveloped DNA, Naked DNA, Naked RNA ) virus with ( Icosahedral, Helical ) symmetry of the capsid.
-It has a ( (+) ss continuous, (-) ss continuous, (-) ss, 3 segment, (-) ss, 8 segment, (-) ss, 2 segment, DS, 10-18 segment, (+) ss, 2 copies ) genome.
-It is virion polymerase ( negative, positive ).
-It's genome size is ( 10, 12, 8, 13-16, 13.5-21, 13.6 ) total in kb.

Erklärung

Frage 17 von 31

1

The Toga family of viruses is classified as a(n):
-Enveloped RNA virus with Icosahedral symmetry of the capsid.
-It has a (-) ss continuous genome.
-It is virion polymerase negative.

Wähle eins der folgenden:

  • WAHR
  • FALSCH

Erklärung

Frage 18 von 31

1

Which family of viruses has the following characteristics?
-Enveloped RNA virus with Icosahedral symmetry of the capsid.
-It has a (+) ss 2 copies genome architecture.
-It is virion polymerase positve.

Wähle eine der folgenden:

  • Retroviruses

  • Flaviviruses

  • Togaviruses

  • Corona viruses

  • Rhabdoviruses

Erklärung

Frage 19 von 31

1

Which of the following family of viruses have a (-) single stranded, non-segmented genome architecture? (Select all that apply)

Wähle eine oder mehr der folgenden:

  • Reoviruses

  • Flaviviruses

  • Togaviruses

  • Retroviruses

  • Coronaviruses

  • Filoviruses

  • Rhabdoviruses

  • Paramyxoviruses

  • Arenaviruses

  • Bunyaviruses

Erklärung

Frage 20 von 31

1

Which of the following can the smallest possible genome size?

Wähle eine der folgenden:

  • Corona viruses

  • Rhabdoviruses

  • Arenaviruses

  • Flaviviruses

  • Picornaviruses

  • Retroviruses

Erklärung

Frage 21 von 31

1

Adenoviruses is a kind of RNA virus

Wähle eins der folgenden:

  • WAHR
  • FALSCH

Erklärung

Frage 22 von 31

1

Herpes virus, Pox viruses, Togaviruses, and Rhabdoviruses are all enveloped viruses

Wähle eins der folgenden:

  • WAHR
  • FALSCH

Erklärung

Frage 23 von 31

1

Which of the following Naked DNA viruses have a linear genome architecture? (Select all that apply)

Wähle eine oder mehr der folgenden:

  • Parvoviruses

  • Papovaviruses

  • Adenoviruses

  • Picornaviruses

  • Arenaviruses

Erklärung

Frage 24 von 31

1

Filoviruses do not have virion polymerases.

Wähle eins der folgenden:

  • WAHR
  • FALSCH

Erklärung

Frage 25 von 31

1

The pox virus is a Helical enveloped DNA virus.

Wähle eins der folgenden:

  • WAHR
  • FALSCH

Erklärung

Frage 26 von 31

1

Which of the following does not go with the others?

Wähle eine der folgenden:

  • Caliciviruses

  • Picornaviruses

  • Flaviviruses

  • Togaviruses

  • Retroviruses

  • Coronaviruses

Erklärung

Frage 27 von 31

1

The virus life cycle:
1. - virus to cellular receptor(s)
2. - endocytosis or fusion of viral envelope with cell membrane
3. -
4. -
• transcription
• translation
• replication
5. - depends on type of virus
6. - generally release by cell ; enveloped viruses release by membrane budding

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    Attachment
    receptor-mediated
    mRNA
    protein
    nucleic acid
    naked viruses
    depends on type of virus
    depends on entry process
    Entry
    Uncoating
    Release
    Assembly
    Replication
    binding
    lysis

Erklärung

Frage 28 von 31

1

Types of Virus Infection

– infection of a permissive cell: results in virus production, may result in cell death (lytic infection)

– infection of a non- or semi-permissive cell: block to virus production at some step so infection
aborts

– long-lasting virus infection. Can be chronic, latent or slow.

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    Acute
    Abortive
    Persistent

Erklärung

Frage 29 von 31

1

Persistent infections:
• -low levels of virus produced over a long time, chronic virus production and reinfection of cells

• - virus goes dormant following primary infection, may reactivate infection at subsequent times

• : virus production increases slowly over time

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    Chronic
    Latent
    Slow

Erklärung

Frage 30 von 31

1

Productive infection- Sequence of events

1.
2. of viral genes

3. Viral

4. of virus particles

5. Generally (but not always) of the host cell

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    Virus enters susceptible cells
    Replication: Transcription / translation
    genome replication occurs
    Assembly, maturation, and release
    results in death

Erklärung

Frage 31 von 31

1

Latent Infection: Sequence of events

1.Virus

2. associated viral genes Viral genes for lytic replication not expressed

3.

4.

5. results in lytic gene expression and production of infectious virus

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    enters susceptible cells
    Transcription / translation of latency
    Maintenance of the viral genome
    No progeny virions produced
    Reactivation of viral gene expression

Erklärung

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