Humans cannot metabolise the cholesterol ring system
Reverse cholesterol transport is mediated by...
HDLs
LDLs
VLDLs
Initially, HDLs are released from the liver with Apo_, in _ form
A1
B100
Pre-Beta-HDL
Pre-Alpha-HDL
Cholesterol Efflux Regulatory Protein is found where?
The liver
Vascular endothelium
Peripheral cells
CERP modifies the cholesterol in the pre-beta-HDL
What does LCAT do that makes the pre-beta-HDL spherical?
The cholesterol is reduced
The cholesterol is esterified
The cholesterol is oxidised
CETP- Cholesterol Ester Transfer Protein
CETP transfers cholesterol esters between
IDLs
The action of CETP makes the HDL smaller
Once the HDL has been made large enough, it returns to the liver to be picked up by
ApoE receptors
LDL receptors
Scavenger receptors
The HDLs picked up transfer the cholesterol to the cell membrane
The returned cholesterol is then excreted as
Free sterol
Cholesterol esters
Bile acids
Xanthomea- Cholesterol depoisiton in the brain
