Pharmacology 1

What are the 3 main types of names used to recognize drugs?

What are the 4 main types of drug classification?

Which type of name does the WHO recommend using within the clinical setting and why?

What is another name for generic drugs?

Which type of drug classification is according to the condition being treated?

Which type of drug classification is based on how the drug achieves its effect?

Which type of drug classification is based on molecular structure?

Which type of drug classification is based on code names used for drugs still within the early stages of development?

What are the 4 major types of Molecular targets?

What are the 3 mechanisms for how drugs work?

How do drugs work?

What is the physiological function of carriers?

Where are Carriers located?

List a clinical example of Carriers as the drug target

What is the physiological function of Enzymes?

What is the difference between competitive and non-competitive enzyme inhibitors

What is substrate?

What is a clinical example of competitive Enzyme inhibitors?

What is a clinical example of non competitive enzyme inhibitors?

What is the physiological function of Receptors?

How many receptors are there in the body?

What is the main drug target?

What are the 4 receptor types?

Where are Ligand gated ion channels located?

What is the structure of ligand gated ion channels?

What is the mechanism of

What is the speed of response from drugs target

Where are G protein coupled receptors located

What is one of the physiological functions of G protein coupled

What is the structure of G protein coupled receptors?

What is the mechanism of G protein coupled receptors?

Why is the G-protein coupled receptor an important drug site?

What are some examples of G-protein receptors?

Where are Enzyme linked, Tyrosine Kinase receptors located?

What is the response time of drugs using G protein coupled receptors

What is the structure of Enzyme linked, tyrosine kinase receptors?

What is Tyrosine Kinase?

What is the mechanism of drugs which target enzyme linked, tyrosine kinase receptors?

What is the speed of response of drugs which target Enzyme linked tyrosine kinase receptors?

Where are nuclear receptors located?

What is the structure of nuclear receptor?

What is the mechanism of nuclear receptors?

What is the speed of response for drugs which target nuclear proteins?

What are agonists?

What are antagonists?

What is selectivity?

What does affinity mean?

What does efficacy mean?

What is the therapeutic index?

What are some genetic sources of PD variability?

How does the process of G-protein coupled receptors drugs work?

What is a drug concentration - response curve (cr curve)?

What is the process that agonist drugs use to produce maximal efficacy?

In regards to agonists what happens when receptors become saturated?

What is the endogenous ligand?

What is a drug's potency?

What is a partial agonist?

Which direction does the CR curve move with competitive antagonists?

How does the CR curve move with no- competitive antagonists

What is the scheduling of medicines and poisons?

List the prescription only drugs and their associated scheduling

List the non-prescription drugs an and their associated scheduling

What are unscheduled drugs?

Why are schedule 8 drugs controlled?

What is drug abuse?

What is tolerance?

What is dependence?

What are 3 generic names for opioids?

What are 3 names for Benzodiazepines?

What are 2 generic names or stimulants/

What are 3 kinds of controlled drugs?

What are 3 things you can do to be safe when administering controlled drugs?

What are some examples of types of drug discovery?

What is some typical criteria for a successful new drug?

What is target selection in drug development?

What is optimisation in drug development?

What is high throughput screening?

What is a chemical library?

What are pharmacodynamics?

What are pharmacokinetics?

What is toxicology?

What is the pharmaceutical aspect of drug development?

What stage of drug development do target selection, optimisation and animal testing occur?

What is acute toxicity in animal testing?

What is sub chronic toxicity in animal testing?

What is chronic toxicity in animal testing?

What is reproductive toxicity in animal testing?

What is the process for cancer testing within the animal testing phase?

What is meant by the term genotoxic in drug safety testing?

What are some drawbacks of pre clinical testing?

What is the motto for administering drugs?

What are the main international controls on drugs signed and ratified by Australia?

What does the UN Single Convention on Narcotic Drugs control?

What does the Government assess therapeutic drugs for when considering drug controls?

Do the State and Territories or the Commonwealth control therapeutic goods?

Does the State and territories or Commonwealth control medicines and poisons?

What is the Therapeutic Goods Act?

True or false: each state/territory has it's own laws/ regulations on drug control?

What do the state and territory laws on drug control deal with?

What does ARTG stand for?

What are the two types of Australian Register of Therapeutic Goods?

What is the difference between AUST L and AUST R?

Who is responsible for scheduling of medicines?

List 5 prescription requirements?

What is PBS?

What is pharmacokinetics?

What are the mechanisms of pharmacokinetics?

How can therapy fail in pharmacokinetics?

What is the therapeutic index?

Why is pharmacokinetics important?

What is meant by patient response variable?

What are some patient response variables which could affect the effectiveness of the drug?

How do you fix problems arising from altered pharmacokinetics?