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FVC Measurements:
Peak Expiratory Flowrate (PEFR)
Maximum achieved during FVC
10 L/s
Nonspecific in significance because it is very dependent on effort
Measured in L/s ATPS corrected to BTPS
Forced Expiratory Flow 200-1200
Average flowrate that occurs during FVC after the first mL has been expired
Typical: 6 L/s
Significance: Measures airflow in airways. Decreased with mechanical airway problems and disease, can be decreased d/t poor effort
Forced Expiratory Flow 25%-75%
Average flowrate during the half of FVC
Typical: 4-5 L/s ATPS corrected to BTPS
Significance: Measures flow in the airways, is in obstructive disease. Most sensitive to detect airway disease. Can appear erroneously if FVC and FEV1 are greatly increased in post bronchodilator studies.
Forced Expiratory Volume/Time (FEVtime)
Volume Expired of time interval
Common: FEV.5, FEV1, FEV2, FEV3, FEV6
ATPS corrected to BTPS
Significance: Decreased flows indicate obstructive disease, FEV1 used to assess improvement in post BD studies, allow 10-15 minutes in between pre/post tests.
FEVT / FVC%
Forced expiratory volume for time interval expressed as a percentage of total FVC
Minimum acceptable values:
FEV.5/FVC = %
FEV1/FVC = %
FEV2/FVC = %
FEV3/FVC = %
FEV6/FVC = %
Significance: with obstructive disease, with restrictive.