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Emma Allde
Mindmap von , erstellt am more than 1 year ago

Medicine Y1 (Theme 1 | Cells and organelles) Mindmap am Th1L07 Competitive and non-competitive inhibitors, erstellt von Emma Allde am 17/08/2016.

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Emma Allde
Erstellt von Emma Allde vor mehr als 8 Jahre
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Th1L07 Competitive andnon-competitive inhibitorsCompetitive inhibitorsNon-competitiveblock the enzyme active siteAlter the apparent Km not theVmaxIncrease the [S] it takes to reachVmaxReduces the steepness of theslopeE.g. MalonateInhibits succinate dehydrogenaseTakes up the active site, blocking succinate (the substrate) from entering thesuccinate dehydrogenasereversible or irreversiblecannot reach the same VmaxKm and Vmax/2 is the sameDoes not directly block the active siteInterfere in some other way with thecatalytic mechanismsirreversibly poisons the enzymee.g. chealator (EDTA)Reversible non-competitiveenzyme inhibitorInhibits Mg2+ requiring enzymeDoppelklick auf diesen KnotenKlicke und ziehe diese Schaltfläche, um einen neuen Knoten zu erstellen