What is hypersensitvity?

What causes hypersensitivity?

Is there only one cause for allergy?

What does the hypersensitivity response result in?

Is the same hypersensitivity mechanism used for useful purpose and for foreign antigen?

What is another name for 'hypersensitivity mechanisms'?

What are the 4 classifications of hypersensitivity?

What are the 2 stages of a hypersensitivity reaction?

What is the process of sensitisation in type 1 hypersensitivity?

What is the hypersensitivity stage of type I?

What is related to mast cell degranulation between 4-24 hours after?

What does the allergen cross link?

What leads to the degranulation of the mast cells?

What may also coat mast cells (reagenic antibody)?

Give 3 other substances that can degranulate mast cells.

Give 3 localised type 1 hypersensitivity disease.

Give 3 systemic type 1 hypersensitivity disease.

How is type 1 hypersensitivity regulated?

What does an increase in Th2 cause?

What 2 cell types will be found in a histological section of a canine asthma-like disease?

Give 7 factors that cause allergy.

What are the 2 things that have influenced the cause of the hygiene hypothesis?

Give 7 factors that influence the hygiene hypothesis.

Is the allergic incidence increasing or decreasing?

What does repeated infection cause with relation to the hygiene hypothesis?

What does lack of microbial exposure cause with relation to the hygiene hypothesis?

What are the 3 ways an antibody can kill a target cell?

Give 3 examples of when there is type II hypersensitivity.

Why might a type II hypersensitivity reaction occur in dogs with transfusion reactions?

Why might a type II hypersensitivity reaction occur in cats with transfusion reactions?

Give 2 outcomes of blood transfusion reactions.

Give an autoimmune disease which is a type II hypersensitivity reaction to the antibody.

What happens in AIHA?

What is the anti-receptor antibodies (subtype of type II hypersensitivity) also referred to as?

Give an example of a receptor stimulating antibody disease in type II hypersensitivity.

How does Grave's disease work?

Give a disease that involves receptor blocking antibodies in type II hypersensitivity.

What happens in Myasthenia Gravis?

What are the clinical signs of Myasthenia Gravis?

What are the 2 sub types of type III hypersensitivity?

What happens in type III when there is antibody in excess?

What can the antigen entering where the antibody is in excess cause?

Give 3 human arthus reactions (occupational diseases).

What happens in type III when there is antigen in excess?

What is the effect of antibody-antigen complex sitting in the wall of a blood vessel when there is excess antigen?

Why do immune complexes fall out of blood vessels?

Give 4 places where it is common to get localisation of circulating immune complexes.

Give 6 factors that determine the immune complex deposition.

What is another term used to describe type IV hypersensitivity?

What is involved in type IV hypersensitivity?

How long does it take for the DTH to occur?

What is stimulated in a DTH?

What cells are recruited by the IFN-gamma?

What is an example of a DTH in human medicine?

What everyday compounds can cause a DHT?

How has veterinary medicine been seen to cause a DTH?

What was the initial purpose of hypersensitivity reactions?

What does a type 1 hypersensitivity reaction help to protect against?

What does a type IV hypersensitivity reaction help to protect against?