Rheumatology_2013

Which is the best clinical feature to differentiate ankylosing spondylitis from mechanical back pain?

A 60 year old male presents with a background of left knee osteoarthritis presents with new onset left knee and posterior lower leg pain. The pain is worse on dorsiflexion.
What is the most likely pathology?

A 30 year old woman presents with bilateral proximal muscle weakness. She is noted to have blanching of the fingers, especially in cold weather.

Anti-Jo: positive
ANA positive
CK 2000s
ESR 60
EMG: myopathic changes

The presence of which of the following conveys the worst prognosis?

30F presents with polyarthralgia and fatigue. Which of the following conditions is a negative ANA most useful for ruling out?

With respect to osteoarthritis of the knee, which of the following is most effective in long-term management of pain?