Erstellt von Sami-Jaine
vor mehr als 11 Jahre
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5 reproductive factors that influence breast cancer risk:
Think link between hormones and cancer may explain...
Oral contraceptives and hormone replacement therapy can...
Pesticides contain _____ that may lead to health problems including cancer.
Central Tolerance:
B cells are matured in the...
Central Tolerance:
T cells are matured in the ....
Double negative T cells →
Large double positive T cells →
Small double positive T cells...
3 things might happen next
Ignorance
Central tolerance occurs in...
Growth regulation in normal cells v neoplastic cells
Definition of Neoplasm
Tumour growth rate is determined by 1 thing and influenced by 2 things
Definition of Tolerance
Peripheral tolerance occurs in...
Definition of Self-Tolerance
Source of the two (co)signals required for full T cell activation
Central tolerance
Immune Surveillance Theory
5 pieces of evidence supporting immune surveillance theory:
1 piece of evidence against immune surveillance theory...
3 means that a tumour may evade the immune system...
Peripheral Tolerance
A stimulus can be physical or chemical and leads to a cell adapting to their environment and reverting back to normal when the stimulus is gone.
Individuals with downs may be susceptible to heart defects, Alzheimer's, hearing, sight, thyroid and digestive problems as well as a specific cancer, namely...
Oncogenes
Anti-oncogenes
Hypertrophy
TP53 gene
Atrophy
Proto-oncogenes
Hyperplasia
Mouse Skin
Applying an initiating agent alone results in...
Mouse Skin
Applying an initiating agent, followed by promoter results in...
Mouse Skin
Delaying the application of promoter several months after applying an initiating agent, results in...
Mouse Skin
Applying promoter alone results in...
Mouse Skin
Applying an initiating agent after the promoter results in...
3 Rules of Infections and Cancer:
3 Rules of Direct Causal Association:
5 factors that contribute to the breakdown of tolerance:
Metaplasia
Dysplasia
carcinomas come from...
Lymphomas, leukaemias and myelomas come from...
Sarcomas come from...