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BioPsych Exam Style Qs Lectures 1- Topics:

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BioPsych Quiz w1-6: TMS, EMG, fMRI, Anatomy and Theories of Memory, Alzhiemers

Frage 1 von 57

1

What determines the shape of the TMS coils?

Wähle eine der folgenden:

  • The model of the machine

  • type and precision of the stimulation needed

  • The kind of and strength of electoral pulse

  • The duration of the test

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Frage 2 von 57

1

How is TMS used in research?

Wähle eine der folgenden:

  • Determining the casual involvement of a brain region

  • To test clinical drugs

  • To visualize brain structures

  • To disable glial cells

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Frage 3 von 57

1

What are clinical applications of TMS?

Wähle eine der folgenden:

  • This option is available in Victoria (e.g., the Victoria Clinic) for depression

  • Shock therapy and hyponosis

  • To disable a problematic part of the brain permantly

  • To subdue a distressed person to sleep

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Frage 4 von 57

1

What are some advantages of EGG?

Wähle eine der folgenden:

  • It is cheap and relatively easy to conduct

  • Temporal resolution is sound

  • A and B

  • The patient is conscious

  • You don't have to be trained to use it

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Frage 5 von 57

1

Essentially one compares the BOLD fMRI signals coming from the brain in two situations

Wähle eine der folgenden:

  • the control and experimental task

  • the control, experimental task and a task to demonstrate the instructions

  • the control, experimental task and a task to demonstrate the instructions and a task to calm them down

  • the control, experimental task and a task to demonstrate the instructions and a task to calm them down and another to measure the size/dynamics of the brain

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Frage 6 von 57

1

ERP studies are used for:

Wähle eine der folgenden:

  • Testing the ability of post trauma patients

  • Healing parts of the brain

  • Teach post trauma patients to rewire thier neurons

  • To study components of well established cognitive processes

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Frage 7 von 57

1

Limits of EGG

Wähle eine der folgenden:

  • Signals in the sulci are harder to detect than from gyri, and may additionally be masked by the signals from the gyri

  • A and D

  • The poor spacial resolution makes it difficult to determine location of ERP

  • The orientation of the neurons determines the sign of the recorded potentials - Some orientations lead to signals which cannot be recorded.

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Frage 8 von 57

1

What adv does fMRI have over PET scans?

Wähle eine der folgenden:

  • fMRI doesn't need radiation

  • fMRI is cheaper and easier to use

  • fMRI the patient can be awake

  • fMRI allows for 3D views of the brain

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Frage 9 von 57

1

What is BOLD?

Wähle eine der folgenden:

  • Blood Oxygen Level-Dependent
    Because the brain sends so much blood to the active area, the oxygen content of the blood actually increases

  • The type of scanning signal

  • Blood Oxygen Leverage-Dependent
    The net gradient in change that occurs when brain activity spikes and the brain loses oxygen

  • Blood Oxytocin Level-Dependent
    Because the patent is nervous, we accept a level of oxycotin spike and compare it against the normal rate

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Frage 10 von 57

1

What is a disadv of BOLD fMRI ?

Wähle eine der folgenden:

  • if two neural events occur within about two seconds of each other, the BOLD fMRI responses to the two events will become confused. Maximum temporal resolution is about 2 seconds.

  • f a given neuron “requests” more blood, all neighbouring neurons within about 1 mm of it will receive an increased blood flow.
    Thus, if two neural events occur within 1 mm of each other, BOLD fMRI will not be able to distinguish them.

  • A and B

  • neither: BOLD measurement compensates for these flaws

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Frage 11 von 57

1

What is a safety concern with fMRI measurements?

Wähle eine der folgenden:

  • The patient may be claustrophibic

  • Any ferromagnetic object brought too close will literally fly into the magnetic, destroying whatever is inside the magnet (e.g. the patient)

  • The liquid hydrogen could leak

  • None of the above

  • Getting he procedure wrong can resultin patient brain injury

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Frage 12 von 57

1

Which process states the physics of the brain scan correctly

Wähle eine der folgenden:

  • None of the below: the process is molecular

  • The slower the decay rate, the greater the neural activity, thus we drip feed signals and see how long it takes for the brain to stop responding completely

  • The slower the decay rate, the greater the neural activity.
    we excite the brain with an RF pulse.

    Then we measured the RF pulse emitted in turn by the brain.

    By measuring how long the brain’s RF pulse takes to decay we can infer the neural activity in that region of the brain.

  • we excite the brain with an RF pulse.

    Then we measured the RF pulse emitted in turn by the brain.

    By measuring how long the brain’s RF pulse takes to decay we can infer the neural activity in that region of the brain.

    The slower the decay rate, the greater the neural activity.

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Frage 13 von 57

1

Cririsms of fMRI include:

Wähle eine der folgenden:

  • Multiple Comparisons Problem- multiple comparisons problem: the more t tests you do, the greater chance there is of reporting a false positive, solved by preforming a Bonferoni Correction test

  • All answers are correct

  • Over Interpretation of Null Results: the failure to prove that a given brain area is involved in a particular task does not prove that the brain area is not involved in the task

  • Non-independent sample selection : use different scanning sessions for the identification and testing of the ROI.

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Frage 14 von 57

1

Epilepsy is caused by:

Wähle eine der folgenden:

  • Inhibitory-excitatory balance: GABA and
    glutamate, due to a reduction in GABA

  • Inhibitory-excitatory balance: GABA and
    glutamate, due to a reduction in glutamine

  • Neurons going through apoptosis at an alarming rate

  • None of the above

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Frage 15 von 57

1

TLE Epilepsy involves

Wähle eine der folgenden:

  • Recurrent unprovoked seizures originating
    from medial (middle/inner or lateral towards the outside temporal lobe”
    Simple partial seizures (without loss of awareness)
    AND Complex partial seizures (with loss of awareness)

  • Recurrent unprovoked seizures originating
    from medial (middle/inner or lateral towards the outside temporal lobe”
    Simple partial seizures (without loss of awareness) but not
    Complex partial seizures (with loss of awareness)

  • Recurrent unprovoked seizures originating
    from medial (middle/inner or lateral towards the outside temporal lobe”
    Not, Simple partial seizures (without loss of awareness) but actually
    Complex partial seizures (with loss of awareness)

  • None of the above

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Frage 16 von 57

1

Hippocampal formation is essential for what functions?

Wähle eine der folgenden:

  • necessary for relational memory tasks eg Paired Associate Learning tasks
    Information is integrated in sensory systems,
    sent to hippocampal formation for long-term
    storage.

  • Information is integrated in sensory systems,
    sent to hippocampal formation for long-term
    storage.

  • necessary for relational memory tasks eg Paired Associate Learning tasks
    Information is integrated in sensory systems,
    sent to hippocampal formation for long-term
    storage.
    Connecting to the temporal neocortex

  • all of the above

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Frage 17 von 57

1

Who was HM?

Wähle eine der folgenden:

  • 27 y.o. man with severe temporal
    lobe epilepsy
    Underwent bilateral
    resection of extensive amount of
    medial temporal tissue. Normal attention span, preserved
    intelligence
    Retrograde memory essentially recovered
    over time. Severe anterograde amnesia
    – Declarative Declarative memory: conscious access to
    information learned previously. Severely impaired vs. procedural memory: remembering ‘how to’. Was ok.

  • 27 year old man who suffered a serious injury by an iron rod piercing his head and frontal cortex
    This led to severe changes in his personality in the 50s

  • Suffered DAT and diagnosed with the disease after memory assessment

  • 50 year old man who suffered a serious injury by an iron rod piercing his head and frontal cortex
    This led to severe changes in his personality in the 50s

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Frage 18 von 57

1

what does damage to papez circuit result in?

Wähle eine der folgenden:

  • result in declarative memory impairment

  • result in declarative memory impairment and procedural memory

  • damage to episodic and procedural memory

  • damage to rely to the amygdala

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Frage 19 von 57

1

What was the research question in Amassian et al. (1989) classical TMS study?

Wähle eine der folgenden:

  • They investigated error processing by applying TMS during the time window of the ERN.

  • They investigated the effects of TMS over primary visual cortex on the perception of letter stimuli. 

  • They investigated the effects of TMS over prefrontal cortex on the perception of letter stimuli.

  • They investigated the effects of TMS over primary motor cortex on mental rotation

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Frage 20 von 57

1

The maximum temporal resolution of fMRI is approximately

Wähle eine der folgenden:

  • 2 ms

  • 20 ms

  • 200 ms

  • 2000 ms

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Frage 21 von 57

1

Which of the following is a safety concern for fMRI?

Wähle eine der folgenden:

  • It involves ingesting a radioactive isotope.

  • The machine may cause people to feel claustrophobic.

  • Patients must fast before having an fMRI scan.

  • It should not be administered to patients with epilepsy.

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Frage 22 von 57

1

What is a typical EEG amplitude?

Wähle eine der folgenden:

  • 10μV to 100μV

  • 1000μV to 100000μV

  • 20μV to 200μV

  • 1μV to 10μV

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Frage 23 von 57

1

Which of the following is NOT one of the four TMS techniques discussed in the lectures?

Wähle eine der folgenden:

  • The "probing excitability" approach

  • The injection of "neural noise"

  • The "simultaneous-pulse approach"

  • The creation of a "virtual lesion"

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Frage 24 von 57

1

The biochemical basis of epileptic seizures is:

Wähle eine der folgenden:

  • an inhibitor that binds to receptors on the post-synaptic membrane, preventing the uptake of glutamate.

  • lesions to the medial or lateral temporal lobe.

  • oversecretion of glutamate.

  • a reduction in GABA uptake.

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Frage 25 von 57

1

What is an advantage of the Electroencephalograph?

Wähle eine der folgenden:

  • The temporal resolution is good 

  • It is not biased to signals generated in superficial layers of cerebral cortex 

  • The spatial resolution is good 

  • Signals from the sulci are easy to detect 

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Frage 26 von 57

1

The memory deficit detailed in the case study of HM is ____ because HM ___

Wähle eine der folgenden:

  • anterograde amnesia; could not remember events from before the incident but could create new memories.

  • retrograde amnesia; could not remember events from before the incident but could create new memories.

  • anterograde amnesia; had access to long-term memory from before the incident but was unable to create new memories post injury.

  • retrograde amnesia; had access to long-term memory from before the incident but was unable to create new memories post injury

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Frage 27 von 57

1

How will a 46 year old individual presenting with two forms of cognition deficits, both amnestic and non-amnestic be diagnosed, according to McKhann et al's criteria for Alzheimer's Disease?

Wähle eine der folgenden:

  • Probable AD

  • Definite AD

  • Possible AD

  • Dementia of the Alzheimer's Type

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Frage 28 von 57

1

How does TMS-induced currents affect neurons?

Wähle eine der folgenden:

  • TMS-induced current causes all neurons within a circumscribed area of cortex to fire towards the anterior and posterior sections of the brain

  • TMS-induced current causes all neurons within a circumscribed area of cortex to fire randomly

  • TMS-induced current causes all neurons within a circumscribed area of cortex to fire in a path align with the magnetic field path

  • TMS-induced current causes all neurons within a circumscribed area of cortex to fire all in the same direction

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Frage 29 von 57

1

What is the main danger associated with fMRI?

Wähle eine der folgenden:

  • ionising radiation

  • seizure

  • strong magnetic field

  • there is no danger associated with fMRI

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Frage 30 von 57

1

what does the bold fMRI measure?

Wähle eine der folgenden:

  • the oxygen level in the blood

  • the magnetic field of the brain 

  • the neural activity in the brain 

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Frage 31 von 57

1

After his operation, HM had trouble with

Wähle eine der folgenden:

  • Retrograde memory 

  • Intelligence and attention span 

  • Anterograde memory formation 

  • Temporal lobe epilepsy 

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Frage 32 von 57

1

A lesion on the left medial temporal lobe results in

Wähle eine der folgenden:

  • emotional memory impairment 

  • verbal memory impairment 

  • non-verbal memory impairment 

  • visual memory impairment 

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Frage 33 von 57

1

Out of four children, one of the girls and one of the boys in a family both share a genetic biological condition. Through genetic family tree mapping, you find out that none of their parents, uncles, aunties and grandparents share this condition. If we are looking at the daughter, what mode of inheritance is this gene? 

Wähle eine der folgenden:

  • Autosomal Recessive

  • Autosomal Dominant

  • X-Linked Recessive

  • None of the above

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Frage 34 von 57

1

what is ltp?

Wähle eine der folgenden:

  • a form of malfunctioned nuerotransmitter

  • A fault in an action potential where it hyperpolizerses for too long

  • When an axon of cell A…excites cell B and repeatedly or persistently takes part in firing it, some growth process or metabolic change takes place in one or both cells so that A’s efficiency as one of the cell’s firing B is increased” Cell B responds more vigiously to cell A next time

  • A form of neuron death

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Frage 35 von 57

1

Declarative memory is _________ with 2 divisions______

Wähle eine der folgenden:

  • a result of procedual memory; explicit and implicit memory

  • Accumulation of facts/data derived from learning experiences
    outcome of processing by various processing systems, which feed the hippocampal formation; Semantic and Episodic

  • Declarative memory is the result of episdic/semantic memory processes

  • Is relational/connective in nature, links between memories rent context based and thus 2 divisions dont exist

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Frage 36 von 57

1

which model is most useful for studing amnesia?

Wähle eine der folgenden:

  • Serial models

  • Parralel models

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Frage 37 von 57

1

Turving's SPI hypothesis states:

Wähle eine der folgenden:

  • Episodic memory is an extension of semantic memory

  • Semantic memory is in charge of episodic memory

  • Retrieval can be supported by either system

  • A and C are correct

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Frage 38 von 57

1

VK study does or doesn't fit in SPI hypothesis:

Wähle eine der folgenden:

  • Yes

  • No

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Frage 39 von 57

1

Whilst there are no definite causes of DAT, some risk factors

Wähle eine der folgenden:

  • Genetic mutation causing early onset DAT (Autosomal dominant)

  • Having DS

  • Head injury

  • All of the above

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Frage 40 von 57

1

What is the key difference between the 2 following points in McKhann's et al. DAT criteria?

Wähle eine der folgenden:

  • PrAD, unlike probA, is assessment in life, the other after death

  • In possible AD, the patient has been by a neuropsychologist if there is variance in the presentation of symptoms, whereas probable AD simply involves the presentation of non-amnesia symptoms

  • There is no difference; on is a continuation of the other

  • Possible AD is assessed by the family, probable by a professional

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Frage 41 von 57

1

The pathology of DAT involves

Wähle eine der folgenden:

  • All of the below

  • Glial cell proliferation

  • Severe Degradation of neutrons

  • Senile plaque formation

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Frage 42 von 57

1

What is te first stage of amnesic presentation

Wähle eine der folgenden:

  • MTL impairment (Antero-retrograde memory)

  • Prefrontal cortex degradation

  • PTL impairment (word finding difficulties)

  • Paritial lobe (visiospacial difficulties)

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Frage 43 von 57

1

MK symptoms include:

Wähle eine der folgenden:

  • All of the below

  • Word finding difficulties due to posterior temportall lobe damage

  • Visiospacial difficulties suggest parietal tlobe damage

  • Recognition and recall memory impairment suggesting MTL impairment

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Frage 44 von 57

1

The hippocampal formation:

Wähle eine der folgenden:

  • Is made up of the entorhinal and perirhinal cortices

  • Is part of the lateral temporal lobes

  • Includes the dentate gyrus and subiculum

  • None of the above

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Frage 45 von 57

1

Temporal lobe epilepsy:

Wähle eine der folgenden:

  • Has taught us much about the semantic memory system

  • Usually causes seizures that are barely noticeable to an observer

  • None of the these

  • Is not usually associated with memory impairment

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Frage 46 von 57

1

Which of the following statements is FALSE?

Wähle eine der folgenden:

  • The frontal lobes incorporate primary memory systems

  • The frontal lobes are essential for relating arbitrarily related pieces of information

  • Damage to the thalamus is unlikely to result in memory impairment

  • All of the above

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Frage 47 von 57

1

Hebb’s rule:

Wähle eine der folgenden:

  • Explains autonoetic awareness

  • Describes longterm depression

  • Describes longterm potentiation

  • Explains why depression can cause memory impairment

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Frage 48 von 57

1

Because fMRI is non-radioactive the same subject can be scanned repeatedly.

Wähle eine der folgenden:

  • true

  • false

  • depends on the subject

  • depends on the scanner

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Frage 49 von 57

1

Longterm potentiation is important because:

Wähle eine der folgenden:

  • It describes how excitatory post synaptic potentials increase as a result of increased stimulus frequency

  • It brings about temporary chemical changes that underpin memory function

  • It only occurs in the temporal lobes and proves that this is the site of primary memory function

  • It describes how inhibitory post synaptic potentials increase as a result of decreased stimulus frequency

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Frage 50 von 57

1

Explicit and implicit memory:

Wähle eine der folgenden:

  • Are the same thing as declarative and procedural memory

  • Are distinguished partially on the basis of whether conscious recollection is used

  • Are useful concepts in understanding human amnestic syndromes

  • Both requrie that the learning and recall environments are the same

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Frage 51 von 57

1

The maximum spatial resolution of fMRI is approximat

Wähle eine der folgenden:

  • 0.1 mm

  • 1 mm

  • 10 mm

  • none of the above

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Frage 52 von 57

1

Vargha-Khadem’s ‘children’:

Wähle eine der folgenden:

  • Revealed important insights about the role of the frontal lobes in memory

  • Demonstrated that the lateral temporal neocortex is essential for semantic memory function

  • Indicated that episodic memory and semantic memory can show a single dissociation in performance during encoding

  • None of the above

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Frage 53 von 57

1

Semantic memory:

Wähle eine der folgenden:

  • Is “knowledge memory”

  • Makes it possible to acquire and retain factual information

  • Does not involve autonoetic awareness

  • All of the above

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Frage 54 von 57

1

Episodic memory:

Wähle eine der folgenden:

  • and semantic memory are both memory systems that make mental "time travel" possible, according to Tulving

  • Contains semantic memory within it

  • Relies on the hippocampal circuit

  • All of the above

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Frage 55 von 57

1

Bonferroni corrections are used to address

Wähle eine der folgenden:

  • the multiple comparisons problem

  • statistical relevance

  • the non-independent sample selection bias

  • the problem of over-interpreting a null result

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Frage 56 von 57

1

Dementia of the Alzheimer’s type (DAT):

Wähle eine der folgenden:

  • Cannot be diagnosed during life

  • Is the dementing syndrome associated with Alzheimer’s disease

  • Can be successfully treated with anti-epileptic drugs

  • Is the process of normal ageing speeded up

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Frage 57 von 57

1

fMRI records radio frequency signals emitted by

Wähle eine der folgenden:

  • hydrogen atoms

  • hydrogen nuclei

  • oxygen atoms

  • oxygen nuclei

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