Mer Scott
Quiz von , erstellt am more than 1 year ago

• Outline the sequence of events that results in the secretion of growth hormone. • Describe the metabolic effects of growth hormone on each type of target cell. • Describe the effects of growth hormone on human growth (during the growth years and after skeletal fusion) • Explain what occurs when there is too much or too little growth hormone secreted during childhood.

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Mer Scott
Erstellt von Mer Scott vor etwa 7 Jahre
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L35: Growth Hormone

Frage 1 von 18

1

What percent of cells in the anterior pituitary are somatotrophs, which produce growth hormone?

Wähle eine der folgenden:

  • 50%

  • 20%

  • 70%

  • 95%

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Frage 2 von 18

1

Choose the incorrect statements.

Wähle eine oder mehr der folgenden:

  • 20% of the cells in the anterior pituitary gland are mammotrophs.

  • 20% of the cells in the anterior pituitary gland are corticotrophs.

  • 50% of the cells in the anterior pituitary gland are thyrotrophs.

  • 5% of the cells in the anterior pituitary gland are somatotrophs.

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Frage 3 von 18

1

SS stands for:

Wähle eine der folgenden:

  • Somatostatin

  • Somastatin

  • Somatostatic

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Frage 4 von 18

1

Somatotrophin is another name for growth hormone.

Wähle eins der folgenden:

  • WAHR
  • FALSCH

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Frage 5 von 18

1

Growth hormone has been able to be produced in vitro since 1979.

Wähle eins der folgenden:

  • WAHR
  • FALSCH

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Frage 6 von 18

1

Wähle von der Dropdown-Liste, um den Text zu vervollständigen.

Growth hormone is a ( peptide, protein ) hormone. It is ( small, long ) (191 amino acids). The secretion of GH is ( pulsatile, continuous ) and has a ( daily, hourly ) rhythm which differs between males and females.

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Frage 7 von 18

1

Growth hormone's half life in the blood is 20-25 minutes.

Wähle eins der folgenden:

  • WAHR
  • FALSCH

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Frage 8 von 18

1

Growth hormone is an exception for hormones because it travels in the .

Klicke und ziehe, um den Text zu vervollständigen.

    peptide
    protein
    blood bound to a protein carrier
    without a protein carrier

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Frage 9 von 18

1

Growth hormone releasing hormone neurons (GHRH neurons) in the are excited and release into the anterior pituitary gland where it stimulates to release growth hormone (GH). GH is released into the bloodstream where it stimulates production in the .
IGF-1 feeds back to the hypothalamus where it more release of GHRH and stimulates to inhibit release of by the anterior pituitary gland.

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    hypothalamus
    GHRH
    somatotrophs
    insulin-like growth factor (IGF-1)
    liver
    inhibits
    somatostatin (SS)
    GH

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Frage 10 von 18

1

Choose the correct statements.

Wähle eine oder mehr der folgenden:

  • Growth hormone release peaks during the night and settles down during the day, but is constantly spiking.

  • The growth hormone secretion peak is less pronounced for males.

  • Release of GH increases with age until it peaks at puberty.

  • The puberty peak of GH release occurs earlier for females than males.

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Frage 11 von 18

1

Growth hormone is essential for until around age 8, rapid growth of in two separate periods, and growth of around puberty.

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    brain development
    height
    reproductive organs

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Frage 12 von 18

1

Growth hormone receptor is a single molecule found in the membrane that does not require activation.

Wähle eins der folgenden:

  • WAHR
  • FALSCH

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Frage 13 von 18

1

Which of these is not a long term effect of growth hormone?

Wähle eine der folgenden:

  • Stimulation of bone and muscle growth

  • Stimulation of mitogenesis (cell division) via IGF-1

  • Stimulation of protein synthesis (in liver)

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Frage 14 von 18

1

Stimulation of mitogenesis via IGF-1 is a direct effect of growth hormone.
Stimulation of protein synthesis in muscle by is an indirect effect of growth hormone.

Wähle eins der folgenden:

  • WAHR
  • FALSCH

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Frage 15 von 18

1

Short term effects of growth hormone are always direct.

Wähle eins der folgenden:

  • WAHR
  • FALSCH

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Frage 16 von 18

1

Choose the correct effects of GH on metabolism(short term effects).

Wähle eine oder mehr der folgenden:

  • Increase in blood glucose by stimulating glucose synthesis (in
    liver)

  • Increase in blood glucose by stimulating cellular uptake of glucose

  • Decrease in triglyceride breakdown in adipose tissue

  • Free fatty acid mobilisation in adipose tissue

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Frage 17 von 18

1

Other hormones important for are thyroid hormones, insulin, cortisol, and estrogen/testosterone.
Thyroid hormone the basal metabolic rate and is essential for development.
Insulin and increase metabolism.
Estrogen/testosterone are essential during .

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    growth
    increases
    nervous system
    glucose
    puberty
    cortisol

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Frage 18 von 18

1

Endocrine disorders can be due to too little GH () or too much GH ().
An of GH can cause gigantism or acromegaly. Acromegaly is an excess of GH in which leads to thickening of , and of soft tissues in the hands, feet and face. A can cause dwarfism.
Endocrine disorders can also result from an issue in the GH . Hyposensitive receptors to GH and the effects are similar to hyposecretion. Hypersensitive receptors to GH and have similar effects to hypersecretion.

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    hyposecretion
    hypersecretion
    excess
    adulthood
    childhood
    bones
    muscles
    deficiency
    receptors
    give little or no response
    overreact

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