Pain Medications

Acetaminophen reduces inflammation.

Acetaminophen may cause severe liver toxicity.

NSAIDs decrease inflammation:

The COX-1 isoenzyme of cyclooxygenase, it is responsible for:

The 2 isoenzymes of cyclooxygenase convert arachidonic acid to prostaglandins.

Opioid agonists reduce pain by binding opiate receptors in the ________.

Opioid antagonists can reverse respiratory depression/sedation and stabilize vital signs within seconds.

Opioid agonists have a drug interaction with ________.

Substance P is the neurotransmitter responsible for relaying pain impulses.

Naloxone and Naltrexone are examples of opioid antagonists.

Competitive inhibition in opioid antagonists means they do not stimulate the receptor they occupy.

When administering Naloxone it is important that there be no opioids in the body or acute withdrawal symptoms may occur.

The issue with Naltrexone is that when administered to an unconscious patient who returns to consciousness abruptly, hyperventilation and tremors may occur.

A __________ anesthetic is given when one needs to depress the CNS.

General anesthetic drugs taken via inhalation allow for shorter term anesthesia than IV types.

Counter-irritation of nerve endings interferes with pain perception.

A very common and serious adverse effect of inhalation anesthetics is a sudden and often lethal increase in body temperature.

NSAIDs help with:

A common salicylate is:

Which of the following, when given to children with flu-like symptoms or chickenpox, increases the risk of Reye’s syndrome?