14241210
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Quiz von Michael Jardine, aktualisiert more than 1 year ago
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Erstellt von Michael Jardine
vor mehr als 6 Jahre
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Frage 1
Frage
(from end of L05 slides)
In a particular cell, a non Watson-Crick base pair (T-G) is formed during DNA replication. What is likely to happen next?
Antworten
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Polymerase *probs* removes it, often via 3' exonuclease activity
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Polymerase *probs* removes it, often via 5' exonuclease activity
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Polymerase *probs* removes it, often via 3' endonuclease activity
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Polymerase *probs* removes it, often via 5' endonuclease activity
Frage 2
Frage
(from end of L05 slides)
How does a frameshift mutation differ from a missense mutation?
Antworten
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Missense affects many codons; Frameshift mutation does not.
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Frameshift affects many codons; Missense mutation does not.
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Frameshift affects many codons; Missense mutation only affects 3.
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Missense affects many codons; Frameshift mutation only affects 3.
Frage 3
Frage
(from end of L05 slides)
Did the fluctuation test show that bacterial cells induce mutation upon exposure to the selective agent (viral infection)? Explain. (well, don’t explain *here*, but be ready to)
Antworten
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No.
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Yes.
Frage 4
Frage
DNA is replicated in:
Antworten
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S phase
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M phase
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G phase
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Cytokinesis
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Telekinesis
Frage 5
Frage
UV:
Antworten
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light has HIGH energy
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light has LOW energy
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damage forms a join between two adjacent bases, usually Thymine (forming a Thymine dimer)
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damage forms a join between two adjacent bases, usually Cytosine (forming a Cytosine dimer)
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damage forms a join between two adjacent bases, usually Adenosine (forming a Adenosine dimer)
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damage forms a join between two adjacent bases, usually Guanine (forming a Guanine dimer)
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damage forms a join between two adjacent bases, usually Adenine (forming a Adenine dimer)
Frage 6
Frage
Which of the following is NOT a type of DNA mutation (necessarily)?
Antworten
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Indels
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Incels
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Transitions
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Transversions
Frage 7
Frage
Types of mutations AT THE PROTEIN-CODING LEVEL. Fill in the blanks:
Silent mutation: [blank_start]________________[blank_end];
Missense mutation: [blank_start]________________[blank_end];
Nonsense mutation: [blank_start]________________[blank_end];
Frameshift [blank_start]________________[blank_end].
Antworten
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bp change, NO amino acid sequence change
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bp change, amino acid change
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bp change, early stop codon
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1bp+ indel, alters reading frame
Frage 8
Frage
UV repair in humans is through:
Antworten
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Nucleotide excision repair
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Enzyme photolyase
Frage 9
Frage
A mutation resulting in COPY NUMBER VARIATION can vary between identical twins. Therefore it happens during:
Antworten
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Mitosis
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Meiosis
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Both of the above
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None of the above
Frage 10
Antworten
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Gene expression of different members of a gene family varying in different parts of the same plant
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Gene expression of different members of a gene family varying in different stages of the same plant's development
Frage 11
Frage
(from end of L06 slides)
Variation in gene regulation = mutations that alter the amount of protein product, without a chance in the amino acid sequence. Basically a regulatory mutation. This can be in which of the following:
Antworten
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promoters
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introns
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5’-UTR
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3’-UTR
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exons
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5’-URT
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3’-URT
Frage 12
Frage
Blonde vs brown-hair is an example of variation in:
Antworten
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gene expression
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aa sequence
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gene splicing
Frage 13
Frage
(from end of L06 slides)
Define a gene family:
Antworten
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A set of several similar genes, formed by duplication of a single original gene
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A set of several copies of identical genes, responsible for varying levels of a single trait
Frage 14
Frage
(from end of L06 slides)
What is a pseudogene?
Antworten
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A non-functional copy of a gene including a regulatory mutation that prevents its expression
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A non-functional copy of a gene including a premature stop codon within the gene that prevents its expression
Frage 15
Frage
(from end of L06 slides)
What are the 2 most likely sources of phenotypic and genomic variation between individuals within a species? (…excluding environmental factors for some reason)
Antworten
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Variation in amino acid sequences
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Regulatory sequences
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Variation in gene number
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Variation in splicing
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Novel genes
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