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Quiz von Med Student , aktualisiert more than 1 year ago
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Erstellt von Med Student
vor etwa 6 Jahre
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Frage 1
Frage
Bactericidal antibacterial drugs:
Antworten
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inhibit the growth of microorganisms
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inhibit the multiplication of microorganisms
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kill the microorganisms
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block the enzyme penicillinase
Frage 2
Frage
Antimicrobials with bactericidal activity are:
Antworten
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beta-lactam antibiotics
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amphenicols and lincosamides
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aminoglycosides
-
quinolones
Frage 3
Frage
Bacteriostatic action means:
Antworten
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inhibition of the growth of microorganisms
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inhibition of the multiplication of microorganisms
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destruction of microorganisms
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inhibition of the enzyme penicillinase
Frage 4
Frage
Bacteriostatic antimicrobials are:
Antworten
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amphenicols
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aminoglycosides
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tetracyclines and macroiides
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lincosamides
Frage 5
Frage
Narrow spectrum antimicrobial drugs are active against:
Antworten
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Gram (+) cocci
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Gram (+) bacteria
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Fungi and viruses
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Parasites
Frage 6
Frage
Antimicrobials with a narrow spectrum of activity are:
Antworten
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classic penicillins
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lincosamides
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aminoglycosides
-
classic macrolides
Frage 7
Frage
Antimicrobials with broad spectrum of activity are:
Antworten
-
cephalosporins
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aminopenicilins
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lincosamides
-
rifamycins
Frage 8
Frage
Antimicrobials that inhibit bacterial cell wall synthesis are:
Antworten
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penicillins
-
cephalosporins
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monobactams
-
tetracyclines
Frage 9
Frage
Antimicrobial that inhibit protein synthesis in microorganisms are:
Antworten
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tetracyclines
-
macrolldes
-
quinolones
-
carbapenems
Frage 10
Frage
Antibiotics that inhibit DNA synthesis in microorganisms are
Antworten
-
cephalosporins
-
quinolones
-
macrolides
-
rifampicin
Frage 11
Frage
Antibiotics that must be avoided during pregnancy are:
Antworten
-
tetracyclines
-
penicillins
-
cephalosporins
-
rifampicin
Frage 12
Frage
Antimicrobial agents with urine excretion are:
Antworten
-
penicillins
-
cephalosporins
-
aminoglycosides
-
quinolones
Frage 13
Frage
Antimicrobial agents with bile excretion are:
Antworten
-
tetracyclines
-
aminoglycosides
-
macrolides
-
sulfonamides
Frage 14
Frage
Optimal combinations of antimicrobial agents are:
Antworten
-
bactericidal antibiotics with bactericidal antibiotics
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tetracyclines with macrolides
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bactericidal antibiotics with bacteriostatic antibiotics
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penicillins with B-lactamase inhibitors
Frage 15
Frage
Tetracyclines
Antworten
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are bactericidal
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ae bacterostatic
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accumulate in tissues- in bones and teeth
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are effective against rickettsiae, mycoplasma, chlamydia
Frage 16
Frage
Which foods and drugs interact with tetracyclines' gastrointestinal absorption?
Antworten
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Vitamin B1
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Yogurt or Cheese
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Fe2+ or Mg2+ containing drugs
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Aminoglycosides
Frage 17
Frage
Adverse drug reactions of tetracyclines are:
Antworten
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nephro-and ototoxicity
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hepatotoxicity
-
yellow-brown discoloration of teeth and frequent tooth decay in children
-
inhibition of bone growth in children
Frage 18
Frage
Tetracyclines are contraindicated in:
Antworten
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pregnancy
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children less than 8 years
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liver failure
-
heart failure
Frage 19
Frage
Macrolide antibiotics are:
Antworten
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Azithromycin (Azatril)
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Roxithromycin (Rulid)
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Clarithroomycin (Klacid)
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Gentamycin
Frage 20
Frage
Macrolides are:
Antworten
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bactericidal
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bacteriostatic
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inhibitors of methylxanthines’ metabolism
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effective against mycoplasmas, Legionella, Chlamydia
Frage 21
Frage
Adverse drug reactions of macrolides include:
Antworten
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gastrointestinal disturbances
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allergy
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hepatotoxicity
-
nephrotoxicity
Frage 22
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Macrolides are contraindicated in:
Antworten
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Pregnancy in the first half
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G-6-PDH deficiency
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Liver failure
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Breastfeeding
Frage 23
Frage
Lincosamides:
Antworten
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are bacteriostatic antibiotics
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are appropriate for the treatment of staphylococcal osteomyelitis
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can be hepato- and haematotoxic
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accumulate in the bone marrow
Frage 24
Frage
Lincosamides are contraindicated in:
Antworten
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pregnancy
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children less than 2 years
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liver failure
-
heart failure
Frage 25
Frage
Chloramphenicol:
Antworten
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is a bactericidal antibiotic
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is effective against Gram (-) microorganisms
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is a tetracycline derivative
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inhibits alcohol dehydrogenase enzyme
Frage 26
Frage
The correct statements for Chloramphenicol are:
Antworten
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It is used as a reserve antibiotic because of many ADRs
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Causes gastrointestinal disbacteriosis
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Can be administered orally
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It Is used for the treatment of tuberculosis
Frage 27
Frage
Adverse drug reactions of Chloramphenicol are:
Antworten
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damage of teeth enamel
-
"gray baby" syndrome
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disulfiram- alcohol reaction
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bone marrow supression (myelotoxicity)
Frage 28
Frage
Chloramphenicol is contraindicated in:
Antworten
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Pregnancy
-
Children less than 2 years
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Alcoholism
-
G-6-PDH deficiency
Frage 29
Frage
Beta-lactam antibiotics are
Antworten
-
penicillins
-
cephalosporins
-
monobactams
-
carbapenems
Frage 30
Frage
Narrow spectrum (classic) penicillins are:
Antworten
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Amoxicillin
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Benzylpeniciliin (Penicilin G)
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Phenoxymethylpenicillin (Ospen)
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Oxacillin
Frage 31
Frage
Broad spectrum semisynthetic penicillins are:
Antworten
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Amoxicillin (Amopen)
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Ampicillin
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Azlocillin
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Gentamycin
Frage 32
Frage
Adverse drug reactions of penicillins are:
Antworten
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allergic reactions
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hepatotoxicity
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anaphylactic shock
-
disbactenosrs (for orally administered broad-spectrum penicillins)
Frage 33
Frage
Penicillins and cephalosporins block the synthesis of:
Antworten
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the bacterial cell wall
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the bacterial membrane
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proteins
-
nucleic acids
Frage 34
Frage
Cephalosporins 1st generation are:
Antworten
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More effective against Gram (+) microorganisms
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Cefalexin and Cefazolin
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Bacteriostatic
-
Some agents are nephrotoxic
Frage 35
Frage
Cephalosporins 2nd generation are:
Antworten
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Bactericidal
-
Cefaclor and Cefamandol
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More effective against Gram (-) organisms: Klebsiella, H. lnfluenzae
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With high bile concentrations (most of them)
Frage 36
Frage
Cephalosporins 3rd generation are:
Antworten
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Cefetamet and Ceftriaxon
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Cefaclor and Cefamandol
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More effective against Gram (-) microorganisms
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Used for treatment of life-threatening infections
Frage 37
Frage
Cephalosporins 4th generation are:
Antworten
-
Cefepim and Cefpifom
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Narrow spectrum antibiotics
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Effective against Gram (-) microorganisms as 3rd generation and against Gram (+) as 1st generation cephalosporins
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Used for treatment of life-threatening infections
Frage 38
Frage
Adverse drug reactions of cephalosporins are:
Antworten
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allergic reactions
-
suppressed vitamin K synthesis
-
hepatotoxicity
-
nephrotoxicity
Frage 39
Frage
Aminoglycoside antibiotics are:
Antworten
-
Gentamaicin
-
Amoxiclav
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Amikacin
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Tobramycin
Frage 40
Frage
The correct statements of aminoglycoside antibiotics are:
Antworten
-
they block protein synthesis and are bactericidal
-
they accumulate in soft tissues and bones
-
they are administrated orally for treatment of urinary infections
-
they are effective against Gram (-) microorganisms
Frage 41
Frage
Adverse drug reactions of aminoglycosides are:
Antworten
-
nephrotoxicity
-
ototoxicity
-
myelotoxlcity
-
hepatotoxiclty
Frage 42
Frage
Aminoglycosides are contraindicated in:
Antworten
-
pregnancy
-
children less than 2 years
-
renal failure
-
liver failure
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