Pharmacology Vet 202 Chapter Ten Study Guide

There are three main considerations that must be made when deciding if an antimicrobial will be a successful choice to control a pathogenic infection. These include all of the following except

A dog is being treated for a Staphylococcal infection with an antibiotic that has a MTD that is lower than the laboratory-determined MIC for this drug-pathogen relationship. Should this antimicrobial be used?

Which of the following organizations is the division of the Centers for Disease Control and Prevention that is responsible for tracking how bacterial resistance and sensitivity profiles change over time?

A strain of E. coli has been exposed to low levels of an antibiotic. The small number of remaining bacteria after this treatment results in a pathogen population that is more resistant to the antibiotic than prior to the treatment. As these bacteria replicate, they pass this resistance profile to their daughter cells. This type of antibiotic resistance transmission is considered

It is important to understand the potential for drug residues when choosing therapies for specific groups of animals. For which of the following animals would drug withdrawal times need to be known?

It is not recommended to treat animals with bacteriostatic drugs such as tetracyclines while simultaneously treating with bacteriocidal drugs such as penicillin. Why?

A bacterial strain was tested at the state veterinary diagnostic laboratory and was shown to be resistant to amoxicillin. Of the following, which would be the best choice to use for treating an infection with this bacterial strain?

Sulfonamides are very wide spectrum antimicrobials that work via disruption of microbial folic acid synthesis. Which of the following statements regarding sulfonamides is not true?

Which of the following drug-adverse effect pairs is incorrect?

What drugs, in addition to anti-inflammatories such as glucocorticoids and antibiotics such as the aminoglycosides, are often included in otic preparations for external ear infections in companion animals?

The lowest concentration of a drug needed to inhibit bacterial growth is called:

If a drug’s MIC is > MTD

It has been shown that there is a strong correlation between antibiotic use in food animals and

When bacteria make physical contact with another bacterium and transfer a plasmid this is called

Residue of a drug that can be found in a food product can be dangerous because

Drugs that target cell wall synthesis are most active against the bacteria’s.

All of the following are penicillins except

Beta-lactams can be a good choice for urinary tract infections because

The addition of ____________ and benzathine to penicillin G delays absorption from IM or SC routes.

Tetracyclines are

Which of the following are not considered primary targets for antimicrobial therapies?

Which of these medications is the odd drug?

Why isn’t gentamicin used to treat bacterial enteritis localized in the colon?

Antibiotics such as kanamycin that function by reaching a relatively high serum level are considered ___________-dependent drugs, while those that need to be in the body continuously are considered ____________-dependent drugs.

A urinary tract infection (UTI) was cultured in the regional veterinary diagnostic laboratory, and MICs were computed based on serial dilution assay. Penicillin had an MIC double the referenced dosage that can be accomplished in the serum. Regardless, the clinician still decided to use penicillin to treat this infection. Why?