Neurologic and Neuromuscular Drugs

Beschreibung

Quiz 3
Jennifer Keough
Quiz von Jennifer Keough, aktualisiert more than 1 year ago
Jennifer Keough
Erstellt von Jennifer Keough vor fast 6 Jahre
13
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Zusammenfassung der Ressource

Frage 1

Frage
Centrally-acting skeletal muscle relaxants are basically Central Nervous System depressants.
Antworten
  • True
  • False

Frage 2

Frage
Direct-acting skeletal muscle relaxants affect:
Antworten
  • a. skeletal muscle
  • b. cardiac muscle
  • c. smooth muscle
  • d. all the above are true

Frage 3

Frage
Neuromuscular blocking drugs work by:
Antworten
  • a. disrupting nerve impulses at motor end plates
  • b. disrupting nerve impulses at post-synaptic neurons
  • c. both the above are true

Frage 4

Frage
Depolarizing neuromuscular blocking drugs are derived from curare alkaloids.
Antworten
  • True
  • False

Frage 5

Frage
The ________________ is that area where a terminal nerve ending innervates a muscle.
Antworten
  • a. motor end plate
  • b. synaptic cleft
  • c. both the above are true

Frage 6

Frage
Curare alkaloids:
Antworten
  • Paralyze the diaphragm preventing breathing
  • cross the blood-brain-barrier
  • make one go unconscious immediately
  • compete with phosphorus involved in muscle contractions

Frage 7

Frage
The antidote for curare alkaloids are ____________ drugs.
Antworten
  • anti-cholinesterase
  • cholinesterase

Frage 8

Frage
Depolarizing neuromuscular blocking drugs cannot be inactivated by cholinesterase.
Antworten
  • True
  • False

Frage 9

Frage
Succinylcholine is metabolized slower than acetylcholine, resulting in:
Antworten
  • Longer muscle paralysis
  • Shorter muscle paralysis
  • Succinylcholine has nothing to do with muscle paralysis

Frage 10

Frage
What are the movement disorders associated with Parkinson's disease?
Antworten
  • a. Muscle rigidity
  • b. Akinesia
  • c. Tremors at rest
  • d. Posture/balance disturbances
  • e. a and d are correct
  • f. c and d are correct
  • g. All the above are correct

Frage 11

Frage
Akinesia is the absence of:
Antworten
  • the power of voluntary movement
  • the ability to think
  • diaphragmatic movement
  • the ability of speech

Frage 12

Frage
The 2 types of therapy for Parkinson's disease are _____________ and ______________ drugs.
Antworten
  • anti-cholinergic; dopaminergic
  • anti-cholinergic; anti-cholinesterase
  • cholinergic; dopaminergic
  • cholinergic; anti-cholinersterase

Frage 13

Frage
Anti-cholinergic drugs inhibit acetylcholine action at parasympathetic receptors.
Antworten
  • True
  • False

Frage 14

Frage
Too much acetylcholine will excite the CNS causing parkinsonian tremor.
Antworten
  • True
  • False

Frage 15

Frage
Dopaminergic drugs act on the brain to improve motor function.
Antworten
  • True
  • False

Frage 16

Frage
Dopaminergic drugs act on the brain to improve motor function.
Antworten
  • True
  • False

Frage 17

Frage
Lavodopa can convert to dopamine:
Antworten
  • a. before crossing the blood-brain-barrier
  • b. after crossing the blood-brain-barrier
  • c. both the above are true

Frage 18

Frage
COMT stands for:
Antworten
  • a. Catechol-O-methyltransferase
  • b. Catechol-OH-methyltransacetylase
  • c. Catecholamine-O-methyltransacetylase
  • d. none of the above are correct

Frage 19

Frage
Another name of 5-HT1-receptor agonists is triptans.
Antworten
  • True
  • False

Frage 20

Frage
5-HT1-receptor agonists and ergotamine preparations are both used in the treatment of:
Antworten
  • migraines
  • musculoskeletal issues
  • seizures
  • Parkinson's disease

Frage 21

Frage
Depolarizing neuromuscular blocking drugs act like ____________.
Antworten
  • acetylcholine
  • norepinephrine
  • epinephrine
  • dopamine

Frage 22

Frage
Physical and psychological dependence are major adverse effects of direct-acting skeletal muscle relaxants.
Antworten
  • True
  • False

Frage 23

Frage
Direct-acting skeletal muscle relaxants interfere with ___________ ions involved in skeletal muscle contraction:
Antworten
  • sodium
  • calcium
  • magnesium
  • phosphorus

Frage 24

Frage
Parkinson's disease:
Antworten
  • a. has a deficiency of dopamine
  • b. has an excess of acetylcholine
  • c. is a movement disorder
  • d. all the above are true

Frage 25

Frage
Another name for anti-cholinergic drugs is ____________ drugs.
Antworten
  • parasympatholytic
  • sympatholytic

Frage 26

Frage
COMT inhibitors are reversible.
Antworten
  • True
  • False

Frage 27

Frage
Triptans are used to treat:
Antworten
  • seizures
  • musculoskeletal issues
  • Parkinson's disease
  • migraines

Frage 28

Frage
Abortive anti-migraine drugs are designed to stop a migraine:
Antworten
  • a. after it starts
  • b. before it starts
  • c. both the above are correct
  • d. neither of the above are correct

Frage 29

Frage
Levodopa needs passage through the blood-brain-barrier to become effective.
Antworten
  • True
  • False

Frage 30

Frage
Carbidopa enhances the effectiveness of Levodopa by preventing its peripheral conversion to dopamine.
Antworten
  • True
  • False

Frage 31

Frage
COMT inhibitors are used in Parkinson patients when the initial therapy begins to wear off.
Antworten
  • True
  • False

Frage 32

Frage
Contraindication for taking triptans includes:
Antworten
  • a. Ischemic
  • b. Cerebrovascular
  • c. Coronary artery disease
  • d. All the above are correct

Frage 33

Frage
Anti-cholinergic drugs inhibit acetylcholine action at sympathetic receptors.
Antworten
  • True
  • False

Frage 34

Frage
For epilepsy and seizures a(an) ______________ drug is usually recommended.
Antworten
  • a. anti-migraine
  • b. COMT inhibitor
  • c. dopaminergic
  • d. anti-convulsant

Frage 35

Frage
To have a higher conversion to dopamine after passing through the blood-brain-barrier, one needs to take ______________.
Antworten
  • a. Levodopa
  • b. Carbidopa
  • c. Levodopa and Carbidopa
  • d. None of the above drugs have anything to do with dopamine

Frage 36

Frage
Anti-convulsant drugs:
Antworten
  • a. Stabilize nerve cells from over excitement
  • b. Elevate seizure thresholds
  • c. Inhibit neuromuscular transmission
  • d. Increase GABA
  • e. All the above are correct

Frage 37

Frage
The neurotransmitter released at motor end plates is:
Antworten
  • a. Norepinephrine
  • b. Dopamine
  • c. Acetylcholine
  • d. Epinephrine

Frage 38

Frage
The effectiveness of ergotamine preparations is increased by drinking coffee.
Antworten
  • True
  • False
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