Frage 1
Frage
Centrally-acting skeletal muscle relaxants are basically Central Nervous System depressants.
Frage 2
Frage
Direct-acting skeletal muscle relaxants affect:
Frage 3
Frage
Neuromuscular blocking drugs work by:
Antworten
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a. disrupting nerve impulses at motor end plates
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b. disrupting nerve impulses at post-synaptic neurons
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c. both the above are true
Frage 4
Frage
Depolarizing neuromuscular blocking drugs are derived from curare alkaloids.
Frage 5
Frage
The ________________ is that area where a terminal nerve ending innervates a muscle.
Frage 6
Antworten
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Paralyze the diaphragm preventing breathing
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cross the blood-brain-barrier
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make one go unconscious immediately
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compete with phosphorus involved in muscle contractions
Frage 7
Frage
The antidote for curare alkaloids are ____________ drugs.
Antworten
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anti-cholinesterase
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cholinesterase
Frage 8
Frage
Depolarizing neuromuscular blocking drugs cannot be inactivated by cholinesterase.
Frage 9
Frage
Succinylcholine is metabolized slower than acetylcholine, resulting in:
Frage 10
Frage
What are the movement disorders associated with Parkinson's disease?
Frage 11
Frage
Akinesia is the absence of:
Frage 12
Frage
The 2 types of therapy for Parkinson's disease are _____________ and ______________ drugs.
Antworten
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anti-cholinergic; dopaminergic
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anti-cholinergic; anti-cholinesterase
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cholinergic; dopaminergic
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cholinergic; anti-cholinersterase
Frage 13
Frage
Anti-cholinergic drugs inhibit acetylcholine action at parasympathetic receptors.
Frage 14
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Too much acetylcholine will excite the CNS causing parkinsonian tremor.
Frage 15
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Dopaminergic drugs act on the brain to improve motor function.
Frage 16
Frage
Dopaminergic drugs act on the brain to improve motor function.
Frage 17
Frage
Lavodopa can convert to dopamine:
Antworten
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a. before crossing the blood-brain-barrier
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b. after crossing the blood-brain-barrier
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c. both the above are true
Frage 18
Antworten
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a. Catechol-O-methyltransferase
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b. Catechol-OH-methyltransacetylase
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c. Catecholamine-O-methyltransacetylase
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d. none of the above are correct
Frage 19
Frage
Another name of 5-HT1-receptor agonists is triptans.
Frage 20
Frage
5-HT1-receptor agonists and ergotamine preparations are both used in the treatment of:
Antworten
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migraines
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musculoskeletal issues
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seizures
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Parkinson's disease
Frage 21
Frage
Depolarizing neuromuscular blocking drugs act like ____________.
Antworten
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acetylcholine
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norepinephrine
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epinephrine
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dopamine
Frage 22
Frage
Physical and psychological dependence are major adverse effects of direct-acting skeletal muscle relaxants.
Frage 23
Frage
Direct-acting skeletal muscle relaxants interfere with ___________ ions involved in skeletal muscle contraction:
Antworten
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sodium
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calcium
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magnesium
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phosphorus
Frage 24
Frage
Parkinson's disease:
Antworten
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a. has a deficiency of dopamine
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b. has an excess of acetylcholine
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c. is a movement disorder
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d. all the above are true
Frage 25
Frage
Another name for anti-cholinergic drugs is ____________ drugs.
Antworten
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parasympatholytic
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sympatholytic
Frage 26
Frage
COMT inhibitors are reversible.
Frage 27
Frage
Triptans are used to treat:
Antworten
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seizures
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musculoskeletal issues
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Parkinson's disease
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migraines
Frage 28
Frage
Abortive anti-migraine drugs are designed to stop a migraine:
Frage 29
Frage
Levodopa needs passage through the blood-brain-barrier to become effective.
Frage 30
Frage
Carbidopa enhances the effectiveness of Levodopa by preventing its peripheral conversion to dopamine.
Frage 31
Frage
COMT inhibitors are used in Parkinson patients when the initial therapy begins to wear off.
Frage 32
Frage
Contraindication for taking triptans includes:
Frage 33
Frage
Anti-cholinergic drugs inhibit acetylcholine action at sympathetic receptors.
Frage 34
Frage
For epilepsy and seizures a(an) ______________ drug is usually recommended.
Antworten
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a. anti-migraine
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b. COMT inhibitor
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c. dopaminergic
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d. anti-convulsant
Frage 35
Frage
To have a higher conversion to dopamine after passing through the blood-brain-barrier, one needs to take ______________.
Frage 36
Frage
Anti-convulsant drugs:
Antworten
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a. Stabilize nerve cells from over excitement
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b. Elevate seizure thresholds
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c. Inhibit neuromuscular transmission
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d. Increase GABA
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e. All the above are correct
Frage 37
Frage
The neurotransmitter released at motor end plates is:
Antworten
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a. Norepinephrine
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b. Dopamine
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c. Acetylcholine
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d. Epinephrine
Frage 38
Frage
The effectiveness of ergotamine preparations is increased by drinking coffee.