Adrenegic Drugs- Pharmacology 4th Year- PMU

Beschreibung

Adrenegic Drugs- Pharmacology 4th Year- PMU
Med Student
Quiz von Med Student , aktualisiert more than 1 year ago
Med Student
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3

Zusammenfassung der Ressource

Frage 1

Frage
According to their mechanism of action the adrenergic agonists can be divided in:
Antworten
  • direct agonists
  • indirect agonists
  • agonists with mixed mechanism of action
  • natural compounds

Frage 2

Frage
α1-adrenoceptors are located on:
Antworten
  • presynaptic neuronal endings
  • postsynaptic neuronal endings
  • blood vessels
  • iris dilator muscle

Frage 3

Frage
β1-adrenoceptors are located on:
Antworten
  • postsynaptic neuronal endings
  • presynaptic neuronal endings
  • myocardial cells
  • juxtaglomerular apparatus in the kidney

Frage 4

Frage
β2-adrenoceptors are located on:
Antworten
  • postsynaptic neuronal endings
  • bronchial smooth muscles
  • liver
  • uterus (womb)

Frage 5

Frage
β3-adrenoceptors are located in:
Antworten
  • adipose tissue
  • urinary bladder
  • presynaptic neuronal endings
  • bronchial smooth muscles

Frage 6

Frage
Pharmacological effects of Epinephrine are:
Antworten
  • positive chronotropic effect
  • blood pressure elevation
  • bronchial smooth muscles dilation
  • elevated levels of blood sugar

Frage 7

Frage
Indications for the clinical use of Epinephrine are:
Antworten
  • anaphylactic shock
  • hypoglycaemia
  • arrhythmia
  • glaucoma with wide iridocorneal angle

Frage 8

Frage
Potential adverse drug reactions of Epinephrine are:
Antworten
  • hypoglycaemia
  • arrhythmia
  • tremor
  • anxiety and restlessness

Frage 9

Frage
Clinical indications for prescribing α1-agonists are:
Antworten
  • arterial hypotension
  • acute rhinitis
  • asthma attack
  • heart block

Frage 10

Frage
Pharmacological effects of the selective β2-agonists are:
Antworten
  • pupillary dilation
  • bronchial dilation
  • blood pressure elevation
  • relaxation of uterine muscle

Frage 11

Frage
Which of the following drugs are selective β2-agonists?
Antworten
  • lsoprenalini sulfas
  • Orciprenalini sulfas
  • Salbutamol
  • Salmeterol

Frage 12

Frage
β2-agonists are indicated in:
Antworten
  • bronchial asthma
  • digitalis intoxication
  • arterial hypertension
  • threatening abortion

Frage 13

Frage
Adverse drug reactions of β2-agonists are:
Antworten
  • finger tremor
  • bronchial dilatation
  • hyperglycemia
  • tolerance

Frage 14

Frage
What are the main features of the indirect-acting adrenergic agonists?
Antworten
  • stimulation of central nervous system
  • drug tolerance and dependence
  • have no effect on the cardio-vascular system
  • used for treatment of narcolepsy and attention deficiency hyperactivity disorder (ADHD)

Frage 15

Frage
Clinically desirable interactions can occur between β2-agonists and:(find correct answer)
Antworten
  • tricyclic antidepressants
  • inhaled corticosteroids
  • inhaled antimuscarinic drugs
  • beta blockers

Frage 16

Frage
Mechanisms of action of the presynaptic adrenolytics are:
Antworten
  • blockade of the presynaptic α2-receptors
  • activation of the presynaptic α2-receptors
  • conversion to a “false“ neurotransmitter
  • blockade of the phosphodiesterase enzyme

Frage 17

Frage
Which of the following drugs act as agonists of the presynaptic α2-adrenoceptors?
Antworten
  • Salbutamol
  • Clonidini hydrochloridum
  • α-Methyldopum (Dopegyt)
  • Sotalol

Frage 18

Frage
Pharmacological effects of Clonidin are:
Antworten
  • decreased peripheral vascular resistance
  • antihypertensive
  • inhibition of gastric secretion
  • antiarrhythmic

Frage 19

Frage
Adverse drug reactions of Clonidin are:
Antworten
  • Dry mouth
  • Drowsiness and depression
  • Hypertensive attacks following abrupt cessation of treatment
  • CNS stimulation

Frage 20

Frage
For Methyldopa is true:
Antworten
  • has antihypertensive effect
  • it is safe in pregnancy
  • could cause drug-induced parkinsonism
  • used to treat threatening abortion

Frage 21

Frage
Which of the following drugs are α1-adrenoblockers?
Antworten
  • Prazosin
  • Doxazosin
  • Clonidin
  • Chlorpromazin

Frage 22

Frage
Pharmacological effects of Prazosin are:
Antworten
  • dilation of the resistive and capacitive vessels
  • antihypertensive
  • relaxation of the muscles in the prostate and bladder neck
  • hyperglycaemia

Frage 23

Frage
Adverse drug reactions of α1-adrenoblockers are:
Antworten
  • orthostatic collapse
  • hypokalemia
  • fluid retention
  • hypoglycaemia

Frage 24

Frage
Which of the following drugs are non-selective β-blockers?
Antworten
  • Atenolol
  • Pindolol
  • Acebutolol
  • Propranolol

Frage 25

Frage
Which of the following drugs are selective β1-blockers?
Antworten
  • Atenolol
  • Pindolol
  • Propranolol
  • Metoprolol

Frage 26

Frage
β-blockers are indicated in case of:
Antworten
  • hypertension
  • bronchial asthma
  • arrhythmia
  • ischaemic heart disease

Frage 27

Frage
Pharmacological effects of B-blockers are:
Antworten
  • bronchodilation
  • negative inotropic effect
  • positive chronotropic effect
  • negative chronotropic effect

Frage 28

Frage
β-blocker approved for topical use in treatment of glaucoma is:
Antworten
  • Bisoprolol
  • Metoprolol
  • Timolol
  • Propranolol

Frage 29

Frage
When applied topically in the eye the B-blocker Timolol will:
Antworten
  • increase the intraocular pressure
  • decrease the intraocular pressure
  • cause miosis
  • cause mydriasis

Frage 30

Frage
Potential adverse drug reactions of β-blockers are.
Antworten
  • hypoglycaemia
  • bronchoconstriction
  • hyperglycaemia
  • nightmares

Frage 31

Frage
For long-term treatment with β-blockers is true:
Antworten
  • up-regulation of B-adrenergic receptors
  • down-regulation of B-adrenergic receptors
  • the therapy should be ceased abruptly
  • the therapy should not be ceased abruptly
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