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Genetics Exam 2 Material for Final

Beschreibung

Includes Exam 2, pre-class quizzes and in class questions.
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Zusammenfassung der Ressource

Frage 1

Frage
The Nobel Prive this year in Physiology or Medicine went to research on:
Antworten
  • Lasers
  • Climate Change
  • Immunotherapy and cancer
  • Improving the welfare of children
  • Discovery of telomers

Frage 2

Frage
The max RF value between 2 genes in coupling is 0.3
Antworten
  • True
  • False

Frage 3

Frage
Which of the following does not represent an aneuploid cell?
Antworten
  • a triploid cell
  • a cell with trisomy
  • a cell with monosomy
  • a cell from an individual with Klinefelter syndrome
  • a cell from an individual with Jacob syndrome

Frage 4

Frage
A child with Down Syndrome could result from
Antworten
  • non-disjunction during meiosis 2
  • non-disjunction during transcription
  • non-disjunction during translation
  • non-disjunction during meiosis 1
  • two of the above

Frage 5

Frage
Live humans can be monosomic for sex chromosomes, but not monosomic for autosomes
Antworten
  • true
  • false

Frage 6

Frage
Use the following conditions to answer the question: A. Turner Syndrome B. Edwards syndrome C. Triple X D. Polypoidy E. None of the above The Human condition where cells have an extra autosome is called-----
Antworten
  • A
  • B
  • C
  • D
  • E

Frage 7

Frage
Use the following conditions to answer the question: A. Turner Syndrome B. Edwards syndrome C. Triple X D. Polypoidy E. None of the above The Human condition where cells have a missing sex chromosome is -----
Antworten
  • A
  • B
  • C
  • D
  • E

Frage 8

Frage
Use the following conditions to answer the question: A. Turner Syndrome B. Edwards syndrome C. Triple X D. Polypoidy E. None of the above This is seen in some plant cells
Antworten
  • A
  • B
  • C
  • D
  • E

Frage 9

Frage
Guanylic acid is a -------
Antworten
  • base
  • nucleoside
  • ribonucleotide
  • amino-acid
  • none of the above

Frage 10

Frage
What is the structure of B DNA?
Antworten
  • Left-handed double helix
  • right-handed alpha helix
  • left handed double helix with 10 bp per turn
  • right-handed double helix
  • none of the above

Frage 11

Frage
The width of DNA is 20 Angstroms
Antworten
  • true
  • false

Frage 12

Frage
Based on Griffith's experiment, the following would kill the mouse
Antworten
  • heat killed IIIS bacteria and live IIR
  • heat killed IIR
  • heat killed IIR and live IIIS
  • two of the above
  • all of the answers are correct

Frage 13

Frage
Which of the following represents DNA synthesis?
Antworten
  • n(AA) --> (AA)n
  • n(dXTP)---> (dXMP)n + nPiP
  • n(XTP)---> (XMP)n + nPiP
  • n(dXMP)---> (dXMP)n + nPiP
  • n(dXMP)---> (XTP)n + nPiP

Frage 14

Frage
Which of the following is/are True regarding DNA polymerase 1?
Antworten
  • it has 5' to 3' polymerase activity
  • it has ligase activity
  • it has 3' to 5' exonuclease activity
  • it has telomerase activity
  • two of the above

Frage 15

Frage
Meselson and Stahl provided experimental evidence for the conservative model of replication.
Antworten
  • True
  • False

Frage 16

Frage
Helicase-----while-----topisomerase-------
Antworten
  • breaks phosphodiester bonds/ breaks hydrogen bonds
  • breaks hydrogen bonds/ breaks phosphodiester bonds
  • breaks peptide bonds/ breaks phosphodiester bonds
  • breaks ionic bonds/ breaks phosphodiester bonds
  • none of the above

Frage 17

Frage
Which of the following statements is/are true concerning DNA replication?
Antworten
  • both leading and lagging strands are synthesized in a 3' to a 5' direction
  • the leading strand is synthesized in a 5' to 3' direction, the lagging strand in a 3' to 5' direction
  • both leading and laggging strands are synthesized in a 5' to 3' direction
  • DNA polymerase 2 is responsible for the bilk of the nucleotide ploymerization
  • none of the above

Frage 18

Frage
After receiving a sample of cells, you determine that the cells contain tus. What can you conclude about these cells?
Antworten
  • they are prokaryotes
  • they might be cancer cells
  • they might be stem cells
  • they are gametes
  • B and C are possible

Frage 19

Frage
The following are TRUE regarding DNA replication in Prokaryotes and Eukaryotes
Antworten
  • Replication is semi-conservative
  • replication is bi-directional
  • replication uses ribosomes
  • replication uses promoter sequences
  • two of the above

Frage 20

Frage
If a DNA molecule has 200 bp then it is--------long
Antworten
  • 3.4 nm
  • 6.8 Angstroms
  • 68 nm
  • 20 nm
  • none of the above

Frage 21

Frage
According to Chargaff's rules if a DNA molecule contains 34% C, then which of the following is true?
Antworten
  • Total pyrimidines is 50%
  • 22% are adenine
  • the four bases are present at 25%
  • the total purines is 44%

Frage 22

Frage
The origins of replication in eukaryotes are called ------ and one would expect to find------
Antworten
  • Pribnow box/ A and T bases
  • OriC/ DnaA, DnaB and DnaC
  • Shine-Delgarno/ start codon
  • ARS/ histones
  • all of the above

Frage 23

Frage
Telomerase extends the 3' single stranded DNA overhand in replication
Antworten
  • true
  • false

Frage 24

Frage
The difference in transcription between eukaryotes and prokaryotes are:
Antworten
  • one uses DNA pol 1 2 and 3 and the other uses different DNA pol enzymes
  • one uses primase and the other does not
  • one uses chromatin remodeling complexes and the other does not
  • one always transbries both the sense and antisense strand of the gene while the other does not
  • all of the above

Frage 25

Frage
The core promoter in prokaryotes is called
Antworten
  • kozak sequence
  • OriC
  • Pribnow box
  • rut sequence
  • operator sequence

Frage 26

Frage
Transcription termination in prokaryotes sometimes requires:
Antworten
  • rho, rut and tus
  • stem loop, telomeres and Nus A
  • term sigma factor and RNA pol 2
  • RNA pol3 and specific transcription factors
  • none of the above

Frage 27

Frage
Which is the sense strand?
Image:
47455497 492385901169466 4456721150256349184 N (binary/octet-stream)
Antworten
  • Top Stand (AB)
  • Bottom Strand (CD)
  • Both
  • neither

Frage 28

Frage
In the diagram, the following are true
Image:
47455497 492385901169466 4456721150256349184 N (binary/octet-stream)
Antworten
  • A refers to 3'
  • C refers to 3'
  • B refers to 5'
  • D refers to 5'
  • above of the above

Frage 29

Frage
What is an example of a ribozyme?
Antworten
  • rRNA
  • tRNA
  • intronic RNA
  • miRNA
  • all of the above

Frage 30

Frage
Enhancer sequences usually bind activators and they are transcribed
Antworten
  • true
  • false

Frage 31

Frage
in prokaryotes the small ribosomal subunit is----while in the eukaryotes it is-----
Antworten
  • 20S, 40S
  • 20S, 50S
  • 30S, 40S
  • 30S, 50S
  • 70S, 80S

Frage 32

Frage
Some of the rRNAs in prokaryotes are ---- while some of the rRNAs in eukaryotes are -----
Antworten
  • 16S rRNA and 18S rRNA / 23S rRNA and 28S rRNA
  • 16S rRNA and 5S rRNA / 18S rRNA and 28S rRNA
  • 23S rRNA and 28S rRNA / 16S rRNA and 28S rRNA
  • 18S rRNA and 5S rRNA / 29S rRNA and 38S rRNA
  • none of the above

Frage 33

Frage
Some of the steps in 5' capping of mRNA involve:
Antworten
  • removing RNA and adding GMP
  • Removing DNA and adding ATP
  • Adding DNA and transfering a methyl group
  • removing a phosphate and adding GMP
  • adding poly A

Frage 34

Frage
In eukaryotes, tRNA ------
Antworten
  • undergoes RNA processing
  • has unusual bases
  • is transported out of the cytoplasm
  • has codon sequences
  • three of the above

Frage 35

Frage
In prokaryotic translation, the first charged tRNA enters into the ribosomal P site and carries the amino acid fmet.
Antworten
  • true
  • false

Frage 36

Frage
Which of the following amino acids exhibits " degeneracy" in the genetic code that CAN be explained by the "Wobble Hypothesis" alone?
Image:
47322998 2191513851089690 6806953428158251008 N Li (binary/octet-stream)
Antworten
  • Tryptophan Trp
  • Arginine Arg
  • Phenylalanine Phe
  • Glutamine Gln
  • Two of the above

Frage 37

Frage
The best description of isoaccepting tRNA molecules is
Antworten
  • different anticodons but same amino acids
  • different codons but same amino acids
  • different anticodons and different amino acids
  • different codons and different amino acids
  • all of the above

Frage 38

Frage
Choose the following answers: A. Kozak sequence B. the A site in the ribosome C. release factors D. uncharged tRNA E. none of the answers are correct Is important in binding to 18S rRNA
Antworten
  • A
  • B
  • C
  • D
  • E

Frage 39

Frage
Choose the following answers: A. Kozak sequence B. the A site in the ribosome C. release factors D. uncharged tRNA E. none of the answers are correct Occupies the E site in translation
Antworten
  • A
  • B
  • C
  • D
  • E

Frage 40

Frage
A possible mechanism of action of an antibiotic could be:
Antworten
  • inhibition of DNA pol (any greek letter)
  • inhibition of DNA gyrase
  • inhibition prokaryotic peptidyl transferase
  • inhibition of movement of RNA out to cytoplasm
  • two of the answers are correct
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