Molecular Biology MCQs

Beschreibung

Quiz am Molecular Biology MCQs, erstellt von Hussain Basheer am 07/06/2019.
Hussain Basheer
Quiz von Hussain Basheer, aktualisiert more than 1 year ago
Hussain Basheer
Erstellt von Hussain Basheer vor etwa 5 Jahre
77
1

Zusammenfassung der Ressource

Frage 1

Frage
Which processes are parts of mRNA maturation?
Antworten
  • splicing
  • 3´ capping
  • formation of double-stranded regions
  • polyadenylation

Frage 2

Frage
Down syndrome is caused by
Antworten
  • a gene mutation
  • a structural chromosomal mutation
  • a numerical chromosomal mutation
  • a frameshift mutation

Frage 3

Frage
During anaphase II of meiosis
Antworten
  • homologues separate and migrate towards opposite
  • sister chromatids separate and migrate towards opposite poles
  • nuclear membrane reforms
  • chromosomes line up in a single line

Frage 4

Frage
What is a promoter
Antworten
  • it is a protein complex
  • it is a nucleotide sequence
  • it is needed for initiation of replication
  • it is crucial for transcription initiation

Frage 5

Frage
A primer is a short sequence of
Antworten
  • RNA where replication starts
  • DNA where transcription starts
  • DNA where replication starts
  • RNA where translation startS

Frage 6

Frage
A primer is a short
Antworten
  • protein sequence where replication starts
  • DNA sequence where transcription starts
  • RNA sequence where replication starts
  • RNA sequence where translation starts

Frage 7

Frage
DNA replication is
Antworten
  • conservative
  • semiconservative
  • dispersive
  • continuous

Frage 8

Frage
Necrosis is
Antworten
  • a result of acute chronic damage
  • controlled genetically
  • characterized by inflammation
  • characterized by rupture of the plasma membrane

Frage 9

Frage
The nucleosome
Antworten
  • is DNA wrapped around a histone octamer
  • contains four types of histone proteins
  • is a complex of DNA and non-histone proteins;
  • contains five types of histone proteins

Frage 10

Frage
RNA Polymerase III transcribes:
Antworten
  • mRNA;
  • 5.8S rRNA
  • tRNA
  • 5S rRNA

Frage 11

Frage
Synapsis occurs during
Antworten
  • mitosis
  • anaphase I
  • prophase I
  • mitosis and meiosis

Frage 12

Frage
Which statements for oogenesis are true?
Antworten
  • it is interrupted process
  • meiosis II is accomplished after fertilization
  • starts during puberty
  • has 4 distinct stages

Frage 13

Frage
Oogenesis begins
Antworten
  • in the embryonic period
  • at birth
  • at puberty
  • in the last week of gestation

Frage 14

Frage
In oogenesis meiosis II is accomplished
Antworten
  • at birth
  • after fertilization
  • before fertilization
  • at ovulation

Frage 15

Frage
A missense mutation
Antworten
  • is an exchange of a coding codon with a STOP codon
  • is an exchange of a coding codon with a codon coding for another amino acid
  • a coding codon with a codon coding for the same aminoacid
  • changes the amino acid sequence of the protein

Frage 16

Frage
tRNA carries
Antworten
  • The amino acid to the nucleuS
  • the rRNA to the mRNA
  • the mRNA to the nucleus
  • the amino acid to the ribosome

Frage 17

Frage
snRNA are localized in the
Antworten
  • nucleus
  • cytoplasm
  • mitochondria
  • cell membrane

Frage 18

Frage
snRNA is used in
Antworten
  • translation
  • splicing
  • polyadenylation
  • transcription

Frage 19

Frage
Helicase
Antworten
  • separates the two DNA strands
  • elongates the newly synthesized strand
  • joins the Okazaki fragments
  • removes the supercoiling

Frage 20

Frage
Necrosis is characterized by
Antworten
  • shrinkage of the cell
  • DNA ladder
  • rupture of the cell membrane
  • genetic program

Frage 21

Frage
In eukaryotes the first amino acid synthesized during translation is
Antworten
  • isoleucine
  • leucine
  • methionine
  • formylmethionine

Frage 22

Frage
Western blotting is a method for detection of:
Antworten
  • RNA
  • DNA
  • proteins
  • lipids

Frage 23

Frage
Southern blotting is a method for detection of:
Antworten
  • RNA
  • DNA
  • sugars
  • proteins

Frage 24

Frage
Northern blotting is a method for detection of
Antworten
  • RNA
  • DNA
  • proteins
  • lipids

Frage 25

Frage
The nitrogen bases in the DNA helix are linked by
Antworten
  • phosphodiester bonds
  • disulfide bridges
  • covalent bonds
  • hydrogen bonds

Frage 26

Frage
In metaphase of mitosis
Antworten
  • the nucleolus breaks down
  • chromosomes are at the equator
  • the nuclear membrane reforms
  • chromosomes move to the opposite poles

Frage 27

Frage
Pyrimidines are
Antworten
  • adenine and guanine
  • adenine and cytosine
  • thymine and guanine
  • thymine and cytosine

Frage 28

Frage
Purines are
Antworten
  • adenine and thymine
  • thymine and guanine
  • adenine and guanine
  • thymine and cytosine

Frage 29

Frage
Mitochondrial DNA is
Antworten
  • linear
  • single-stranded
  • inherited paternally
  • circular

Frage 30

Frage
If the mRNA has 90 codons, then the polypeptide chain is made of
Antworten
  • 270 amino acids
  • 30 aminoacids
  • 90 amino acids
  • 60 amino acids

Frage 31

Frage
. mRNA
Antworten
  • carries the amino acid to the ribosome
  • is synthesized in the cytoplasm
  • is the template for translation
  • contains rRNA genes

Frage 32

Frage
The acrosomal reaction
Antworten
  • enables the entry of the sperm cell into oocyte
  • enables fusion of the male and female pronuclei
  • prevents polyspermy
  • completes meiosis II of the oocyte

Frage 33

Frage
The cortical reaction
Antworten
  • enables the entry of the sperm cell into the oocyte
  • enables the fusion of the male and female pronuclei
  • prevents polyspermy
  • changes the membrane potential of the sperm cell membrane

Frage 34

Frage
Crossing-over occurs during
Antworten
  • anaphase I
  • prophase I
  • mitosis
  • metaphase

Frage 35

Frage
Okazaki fragments form in the process of:
Antworten
  • transcription
  • translation
  • splicing
  • replication

Frage 36

Frage
. A missense mutation changes the
Antworten
  • amino acid sequence of the protein
  • open reading frame of the gene
  • order of codons within the gene
  • position of the TATA box in the promoteR

Frage 37

Frage
PCR is a method for amplification of
Antworten
  • RNA
  • DNA
  • sugars
  • proteins

Frage 38

Frage
47 XX+21 is the genetic formula of a female with
Antworten
  • Turner syndrome
  • Down syndrome
  • Kleinfelter syndrome
  • Edwards syndrome

Frage 39

Frage
A male with a karyotype 47, XXY has
Antworten
  • Turner syndrome
  • Kleinfelter syndrome;
  • Down syndrome
  • Edwards syndrome

Frage 40

Frage
A female with a karyotype 45, X0 has
Antworten
  • Turner syndrome
  • Kleinfelter syndrome
  • Down syndrome
  • Edwards syndrome

Frage 41

Frage
The genetic formula 45, XO is typical of
Antworten
  • Down syndrome
  • Kleinfelter syndrome
  • Turner syndrome
  • Edwards syndrome

Frage 42

Frage
Turner syndrome is
Antworten
  • trisomy of the X chromosome
  • monosomy of the X chromosome
  • monosomy of the Y chromosome
  • trisomy of the Y chromosome

Frage 43

Frage
Edwards syndrome is a trisomy of chromosome
Antworten
  • 12
  • 21
  • 23
  • 18

Frage 44

Frage
In proteins amino acids are linked by
Antworten
  • peptide bonds
  • disulfide bridges
  • hydrogen bonds
  • triphosphate bridges

Frage 45

Frage
In anaphase of mitosis
Antworten
  • The nucleolus breaks down
  • chromosomes are at the equator
  • the nuclear membrane reforms
  • chromosomes move to the opposite poles

Frage 46

Frage
In meiosis sister chromatids separate during
Antworten
  • metaphase I
  • telophase II
  • anaphase II
  • prometaphase I

Frage 47

Frage
An enhancer is a
Antworten
  • nucleotide sequence
  • protein complex
  • transcription factor
  • ribozyme

Frage 48

Frage
In DNA nucleotides are linked by
Antworten
  • phosphodiester bonds
  • disulfide bridges
  • covalent bonds
  • hydrogen bonds

Frage 49

Frage
The functions of miRNAs are
Antworten
  • coding
  • enzymatic
  • transporting
  • regulatory

Frage 50

Frage
The nitrogen bases in the DNA helix are linked by
Antworten
  • phosphodiester bonds
  • disulfide bridges
  • covalent bonds
  • hydrogen bonds

Frage 51

Frage
The 5’ cap is important for
Antworten
  • snRNA stability
  • formation of the spliceosome
  • termination of transcription
  • mRNA transport into the cytoplasm

Frage 52

Frage
The TATA sequence is commonly found in:
Antworten
  • telomeres
  • centromeres
  • promoters
  • enhancers

Frage 53

Frage
In meiosis sister chromatids separate during
Antworten
  • metaphase I
  • telophase II
  • anaphase II;
  • prometaphase I

Frage 54

Frage
The Robertsonian translocation is a
Antworten
  • structural chromosomal mutation
  • gene mutation
  • point mutation
  • separation of metacentric chromosomes.

Frage 55

Frage
Which proteins control the cell cycle?
Antworten
  • snRNPs
  • activators
  • CDKs
  • promoters

Frage 56

Frage
Polyadenylation occurs at
Antworten
  • the 5’ end of DNA during replication
  • the 3’ end of rRNA during transcription
  • the 5’ end of mRNA during transcription
  • the 3’ end of mRNA during transcription

Frage 57

Frage
The spliceosome contains
Antworten
  • transcription factors
  • endonucleases
  • snRNPs
  • enhancers

Frage 58

Frage
Capacitation is a reaction that occurs in
Antworten
  • oogenesis
  • spermatogenesis
  • fertilization
  • meiosis

Frage 59

Frage
The START codon for translation is
Antworten
  • AAU
  • AUU
  • AUG
  • AUC

Frage 60

Frage
How many types of rRNA exist in eukaryotes?
Antworten
  • 1
  • 2
  • 3
  • 4

Frage 61

Frage
DNA replication takes place during
Antworten
  • S phase
  • G1 phase
  • metaphase
  • telophase

Frage 62

Frage
Prokaryotic mRNA
Antworten
  • is monocistronic
  • contains introns;
  • has a 5’ cap
  • has more than one cistron

Frage 63

Frage
Heterochromatin
Antworten
  • contains functional genes
  • is decondensed
  • replicates late in the S phase
  • is lightly stained

Frage 64

Frage
Euchromatin
Antworten
  • is darkly stained
  • is replicated late in the S phase
  • contains functional genes
  • is highly condensed

Frage 65

Frage
Apoptosis
Antworten
  • causes inflammation
  • is under genetic control
  • is caused by rupture of the cell membrane
  • causes enlargement of the cell

Frage 66

Frage
Which enzymes promote apoptosis?
Antworten
  • snRNPs
  • topoisomerases
  • polymerases
  • caspases

Frage 67

Frage
Intron is the
Antworten
  • coding region of a gene
  • non-coding region of a gene
  • 2 nucleotides that code for one amino acid
  • 3 nucleotides that code for one amino acid

Frage 68

Frage
Exon is the:
Antworten
  • coding region of a gene
  • non-coding region of a gene
  • 2 nucleotides that code for one amino acid
  • 3 nucleotides that code for one amino acid

Frage 69

Frage
Spermatogenesis
Antworten
  • is an interrupted process
  • begins at birth
  • has 4 distinct stages
  • is very inefficient

Frage 70

Frage
The consequence of a nonsense mutation is
Antworten
  • change in the amino acid sequence
  • truncated protein
  • shift of the open reading frame
  • different codon order

Frage 71

Frage
The first AUG sequence in eukaryotes is located in the
Antworten
  • Shine-Dalgarno sequence
  • Kozak sequence
  • Pribnow box
  • TATA box

Frage 72

Frage
Kozak sequence
Antworten
  • tRNA
  • mRNA
  • rRNA
  • snRNA

Frage 73

Frage
Which method is used for DNA amplification?
Antworten
  • Southern blot
  • Northern blot
  • PCR
  • RT-PCR

Frage 74

Frage
Which enzyme is not involved in DNA replication?
Antworten
  • RNA polymerase
  • ligase
  • RNA primase
  • telomerase

Frage 75

Frage
The acrosome is:
Antworten
  • an organelle at the tip of the sperm cell
  • the site where the flagellum of the sperm cell begins
  • an organelle in the perivitelline space of the oocyte
  • the vitelline envelope of the sperm cell

Frage 76

Frage
The polypeptide chain is built up of
Antworten
  • fatty acids
  • amino acids
  • disaccharides
  • polysaccharides

Frage 77

Frage
In oogenesis meiosis II is accomplished
Antworten
  • at birth
  • after fertilization
  • before fertilization
  • at ovulation

Frage 78

Frage
The nucleosome
Antworten
  • Contains H2A, H2B, H3, H4 histone molecules;
  • contains 2 types of histone molecules
  • is DNA wrapped around a non-histone octamer
  • contains 6 types of histone molecules

Frage 79

Frage
The ribosome is a complex of
Antworten
  • DNA and proteins
  • mRNA and tRNA
  • rRNA and polysaccharides
  • rRNA and proteins

Frage 80

Frage
Restriction enzymes are used in
Antworten
  • DNA replication
  • DNA cloning
  • RNA replication
  • RNA restriction

Frage 81

Frage
Which nucleic acid functions as a ribozyme?
Antworten
  • mRNA
  • DNA
  • rRNA
  • ssDNA

Frage 82

Frage
Plasmids are circular DNAs in
Antworten
  • mammalian cells
  • viruses
  • bacterial cells
  • sperm cells

Frage 83

Frage
. The nucleosome contains
Antworten
  • an octamer of histones and 246 bp of DNA
  • an octamer of histones and 146 bp of DNA
  • a hexamer of histones and 146 bp of DNA
  • a hexamer of histones and 146 bp of RNA

Frage 84

Frage
SSB proteins are required for
Antworten
  • transcription
  • translation
  • splicing
  • replication

Frage 85

Frage
Which enzyme does not take part in DNA replication?
Antworten
  • helicase
  • ligase
  • RNA primase
  • RNA polymerase

Frage 86

Frage
Which enzyme unwinds DNA?
Antworten
  • DNA-polymerase
  • helicase
  • transferase
  • topoisomerase

Frage 87

Frage
What is the sequence of the mRNA, if the DNA antisense strand is AATCCGGAT?
Antworten
  • 5’ ATCCGGATT 3’
  • 5’ TTAGGCCTA 3’
  • 5’ AUCCGGAUU 3’
  • 5’ UUAGGCCUA 3’

Frage 88

Frage
Topoisomerase
Antworten
  • removes supercoiling of DNA
  • separates the two DNA strands
  • destroys the nuclear envelope
  • forms the peptide bond
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