Protein trafficking

Which trafficking pathway is highlighted in the picture?

The depicted trafficking pathway is regulated by cellular signals.

Which experiment is a genetic approach to characterize the components and the molecular mechanism of the endomembrane system?

Which experiments make use of microsomes to study the endomembrane system?

Which is the organelle with the largest surface area?

The signal sequence is a short stretch of [blank_start]hydrophobic[blank_end] amino acids at the [blank_start]N-terminus[blank_end] of a nascent protein that serves as an [blank_start]ER-targeting[blank_end] signal.

SRP stands for "[blank_start]signal recognition particle[blank_end]".

Which of the following is a multi-protein complex with an hour-glass shaped aqueous pore?

TMD stands for "[blank_start]transmembrane domain[blank_end]".

TMD is a short stretch of hydrophobic amino acids which serves as a [blank_start]stop transfer sequence[blank_end].

UPR ([blank_start]unfolded protein response[blank_end]) initiates pathways that lead to either the production of more chaperone protein or a global reduction in protein synthesis to alleviate ER stress.

The process in which misfolded proteins are shuttled out of the ER to the [blank_start]cytosol[blank_end] where the oligosaccharide chain is removed and the protein is degraded in the [blank_start]proteasome[blank_end] is called [blank_start]ERAD[blank_end] ([blank_start]ER-associated degradation[blank_end]).

During core modification of a glycoprotein, the last remaining glucose is removed by

UGGT is an ER chaperone which recognizes [blank_start]hydrophobic[blank_end] regions of misfolded proteins and tags them for refolding by adding back a [blank_start]glucose[blank_end] molecule.

In the endomembrane system, the new membrane can only arise from the existing membrane.

According to current knowledge, which of the following are not components of the endomembrane system?