Frage 1
Frage
Where do endocrine cells secrete their hormones into?
Antworten
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Target cells
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Blood
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Out of ducts
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Glands
Frage 2
Frage
What is a neuroendocrine cell?
Antworten
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A cell that released hormones into the blood upon depolarisation
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A cell that releases neurotransmitter into the blood upon depolarisation
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A cell that releases hormones across the synaptic cleft upon depolarisation
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A cell that releases hormones onto neighbouring cells upon depolarisation
Frage 3
Frage
What type of chemical signalling occurs when a cell targets itself?
Antworten
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Autocrine
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Paracrine
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Endocrine
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Neuroendocrine
Frage 4
Frage
What type of chemical signalling occurs when a cell targets a neighbouring cell?
Antworten
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Paracrine
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Autocrine
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Endocrine
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Neuroendocrine
Frage 5
Frage
What type of signalling occurs when a cell releases a signal into the blood to be carried to its distant target cell?
Antworten
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Paracrine
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Autocrine
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Endocrine
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Neuroendocrine
Frage 6
Frage
Which of the following hormones are secreted by neurosecretory cells?
Frage 7
Frage
Which of the following hormones are secreted by epithelial tissues?
Frage 8
Frage
What gives a hormone a long half-life?
Frage 9
Frage
The following questions will be about protein/peptide hormones. What must happen to preprohormones to form active prohormones?
Frage 10
Frage
How are active protein/peptide hormones released?
Frage 11
Frage
Are protein/peptide hormones protein-bound in circulation?
Frage 12
Frage
Which is true of protein hormones in circulation?
Antworten
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Long half-life
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Short half-life
Frage 13
Frage
The following questions will be about steroid hormones. What are steroid hormones derived from?
Antworten
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Cholesterol
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Proteins
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Amines
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DNA
Frage 14
Frage
Steroid hormones are lipid soluble.
Frage 15
Frage
Steroid hormones are stored in glands.
Frage 16
Frage
Are steroid hormones protein-bound in circulation?
Frage 17
Frage
Which is true of steroid hormones?
Antworten
-
Long half-lives
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Short half-lives
Frage 18
Frage
The following questions will be about amine hormones. Most amine hormones are derived from...?
Antworten
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Tyrosine
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Phenylalanine
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Glutamate
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Aspartate
Frage 19
Frage
Thyroid hormones are amine hormones.
Frage 20
Frage
Which subtype of amine hormone is lipid-soluble?
Frage 21
Frage
Which subtype of amine hormone is water-soluble?
Frage 22
Frage
Which subtype of amine hormone is protein-bound in circulation, thus giving it a long half-life?
Frage 23
Frage
Which subtype of amine hormone is not bound to protein in circulation, giving it a short half-life?
Frage 24
Frage
Which subtype of amine hormones are stored intracellulary in secretory granules?
Frage 25
Frage
What are eicosanoids?
Frage 26
Frage
What are eicosanoids derived from?
Antworten
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Arachidonic acid
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Diacylglycerol
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Inositol
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PIP2
Frage 27
Frage
Which of the following is an example of an eicosanoid?
Antworten
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Prostaglandin
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Catecholamine
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Adrenaline
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Parathyroid hormone
Frage 28
Frage
Which of the following hormones have intracellular receptors that alter gene transcription?
Frage 29
Frage
Which of the following hormones have membrane-bound receptors that initiate second-messenger pathways to change enzyme activity?
Antworten
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Steroid hormones
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Thyroid hormones
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Protein/peptide hormones
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Glycoproteins
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Catecholamines
Frage 30
Frage
Drag and drop the correct answers to describe the mechanism of steroid hormones.
1. The steroid hormone crosses the membrane as it is [blank_start]lipid[blank_end]-soluble.
2. The steroid hormone binds to its receptor in the cytosol or [blank_start]nucleus[blank_end].
3. The receptor undergoes a [blank_start]conformational shape change[blank_end] that allows it to bind to DNA.
4. The receptor forms a [blank_start]dimer[blank_end] with another receptor unit and binds to DNA.
5. Binding alters [blank_start]transcription[blank_end] of target genes.
Frage 31
Frage
Which of the following can control hormone secretion?
Antworten
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Change in plasma ion concentration
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Change in plasma nutrient concentration
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Neurotransmitter release from neurones contacting endocrine cells
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Upstream hormone/paracrine agents acting on endocrine cells
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Conscious effort
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Repetitive limb movement
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Lipolysis
Frage 32
Frage
Drag and drop the correct labels to describe the anatomy of the pituitary gland.
Frage 33
Frage
During the development of the pituitary gland, the outpouching of what will form the posterior pituitary/neurohypophysis?
Frage 34
Frage
During the development of the pituitary gland, the outpouching of what will form the anterior pituitary/adenohypophysis?
Frage 35
Frage
Drag and drop the correct labels to describe the development of the pituitary gland.
Frage 36
Frage
Which of the following are secreted by the posterior pituitary/neurohypophysis?
Frage 37
Frage
Drag and drop the correct answers to describe the secretion of hormones by the posterior pituitary gland/neurohypophysis.
1. Specific neural stimuli lead to the synthesis of hormones in [blank_start]cell bodies[blank_end] of [blank_start]hypothalamic[blank_end] nuclei.
2. The hormones are transported down the [blank_start]axons[blank_end] of [blank_start]neuroendocrine[blank_end] cells.
3. The hormones are stored in [blank_start]Herring bodies[blank_end] in the nerve terminals.
4. The hormones are released directly into the [blank_start]venous blood[blank_end] of the posterior pituitary.
Antworten
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cell bodies
-
hypothalamic
-
thalamic
-
cortical
-
axons
-
neuroendocrine
-
endocrine
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paracrine
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Herring bodies
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pituicytes
-
venous blood
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tissue fluid
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surrounding CSF
Frage 38
Frage
What is the effect of ADH?
Antworten
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Increased water resorption in the kidney
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Decreased water resorption in the kidney
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Increase in uterine contractions
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Stimulation of the adrenal glands
Frage 39
Frage
Oxytocin increases uterine contractions during birth as well as milk ejection during suckling.
Frage 40
Frage
Drag and drop the correct answers to describe the mechanism of secretion of hormones from the anterior pituitary/adenohypophysis.
1. Specific neural stimuli lead to [blank_start]synthesis[blank_end] and release of [blank_start]hypothalamic[blank_end] hormones.
2. Hypothalamic hormones are released by [blank_start]neuroendocrine[blank_end] cells into blood vessels at the [blank_start]median eminence[blank_end].
3. The hypothalamic hormones travel down [blank_start]portal blood vessels[blank_end].
4. The hypothalamic hormones control release of anterior pituitary hormones.
Frage 41
Frage
Which part of the pituitary gland receives direct supply from the hypophyseal arteries?
Frage 42
Frage
Drag and drop the correct labels to describe the vasculature of the pituitary gland.
Antworten
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Supraoptic nuclei
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Paraventricular nuclei
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Superior hypophyseal artery
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Infundibulum
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Inferior hypophyseal artery
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trabecular artery
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Hypophyseal veins
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Endocrine cells
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Anterior pituitary/adenohypophysis
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Posterior pituitary/neurohypophysis
Frage 43
Frage
Which of the following are secreted by the anterior pituitary/adenohypophysis?
Frage 44
Frage
What do the hypothalamic hypophysiotrophic hormones do?
Antworten
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Stimulate endocrine cells in the anterior pituitary/adenohypophysis to secrete hormones
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Stimulate the release of hormones from the Herring bodies in the posterior pituitary/neurohypophysis
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Increase body temperature
-
Initiate reproductive behaviour
Frage 45
Frage
Drag and drop the correct labels to describe the effect of hypothalamic hypophysiotrophic hormones on the anterior pituitary/adenohypophysis.
Antworten
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Thyrotropin-releasing hormone
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Dopamine
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Corticotropin-releasing hormone
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Gonadotrophin-releasing hormone
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Growth-hormone releasing hormone
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Somatostatin
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Thyrotroph cells
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Lactotroph cells
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Corticotroph cells
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Gonadotroph cells
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Somatotroph cells
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Thyroid-stimulating hormone
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Prolactin
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Adrenocorticotrophic hormone
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Luteinising hormone
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Follicle-stimulating hormone
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Growth hormone