Transfusion Science Multiple Choice Questions

Beschreibung

Includes Kell, Kidd, Duffy, Lutheran, MNS, Lewis and more
p12227277
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p12227277
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Zusammenfassung der Ressource

Frage 1

Frage
Which one of the following is NOT true about Kell system antibodies
Antworten
  • Usually clinically significant IgG antibodies
  • Best detected in indirect antiglobulin tests
  • Fail to react in enzyme tests
  • Do not activate complement

Frage 2

Frage
Antibodies to the Kell, Kidd and Duffy systems all share the following traits except
Antworten
  • Can cause haemolytic disease of the newborn and foetus
  • Enhanced with enzyme treatment
  • Can cause haemolytic transfusion reactions
  • usually detected only by indirect antiglobulin test

Frage 3

Frage
Which of the following phenotypes is heterozygous
Antworten
  • Fy(a-b+)
  • Jk(a+b+)
  • Lu(a-b-)HIV
  • Jk(a-b+)

Frage 4

Frage
Which of the antibodies from the following blood group systems shows a dosage effect?
Antworten
  • Lutheran
  • Kell
  • Duffy
  • P
  • Lewis

Frage 5

Frage
Antibodies to k antigen are not commonly detected in transfusion screening because
Antworten
  • k antigen is of high incidence
  • the antibodies do not cause transfusion reactions
  • antibodies best react at 4 degree (C)
  • The antigen is of low incidence
  • k antigen is not present on screening cells

Frage 6

Frage
Lewis system antibodies have not been implicated in haemolytic disease of the new born and foetus because
Antworten
  • the antigens are not fully developed at birth
  • Lewis system antibodies do not cross the placenta
  • the antibodies are not clinically significant
  • the antigens are primarily plasma based
  • All of the above

Frage 7

Frage
The Donath-Landsteiner antibody is
Antworten
  • an IgG auto anti-P
  • an IgM auto anti-P
  • an IgM auto anti-I
  • anti-IH that reacts at cold temperatures

Frage 8

Frage
Which of the following cells has the highest concentration of M antigens
Antworten
  • MNSs
  • MNs
  • NSs
  • MSs
  • NS

Frage 9

Frage
Which of the following does not result in an Lu(a-b-) phenotype
Antworten
  • Deletion of the genes on the Lu locus
  • Amorphic genes of the Lu locus
  • Delayed anamestic heamolytic transfusion reaction
  • A suppressor gene on the X-chromosome
  • An inhibitor gene on another locus

Frage 10

Frage
The top and bottom pack comprises of
Antworten
  • Single packs joined together
  • Triple pack
  • Double pack
  • Quadruple pack
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