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Frage 1
Frage
What triggers the activation of the adaptive immune system?
Antworten
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Pathogen exposure
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Inflammation
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Antibody production
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Phagocytosis
Frage 2
Frage
There are two components of the adaptive immune system. What are they called?
Antworten
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Cellular immune system
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Humoral immune system
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Antigenic immune system
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Cytotoxic immune system
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Acquired immune system
Frage 3
Frage
What happens to the response of the immune system on each repeated exposure to a pathogen?
Antworten
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It becomes faster
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It becomes more specific
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It causes more inflammation
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It becomes less efficient
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It involves more components of the immune system
Frage 4
Frage
What cells are involved in humoral immunity?
Antworten
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B cells
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T cells
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Natural killer cells
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Phagocytes
Frage 5
Frage
What cells are involved in cellular immunity?
Antworten
-
B cells
-
T cells
-
Phagocytes
-
Natural killer cells
Frage 6
Frage
Which part of the adaptive immune system produced antibodies?
Antworten
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Humoral
-
Cellular
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Both
Frage 7
Frage
The adaptive immune system is able to remember pathogens in case they present again. True or false?
Antworten
- True
- False
Frage 8
Frage
Which cells express CD4?
Antworten
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T helper cells
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T killer cells
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T regulatory cells
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Plasma B cells
Frage 9
Frage
What is the function of T helper cells?
Antworten
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Activate macrophages
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Help B cells to produce antibodies
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Remember the pathogen in case of repeat infection
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Produce antibodies
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Activate natural killer cells
Frage 10
Frage
Why do we need T regulatory cells?
Antworten
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To control the immune response
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To ensure the immune response is specific
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To prevent the immune system from attacking healthy cells
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To prevent the immune system from attacking normal flora
Frage 11
Frage
Which cells expressed CD8?
Antworten
-
T killer cells
-
T helper cells
-
T regulatory cells
-
Plasma B cells
Frage 12
Frage
Which cells have the longest life-span?
Antworten
-
T regulatory cells
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Memory B cells
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Plasma B cells
-
T helper cells
Frage 13
Frage
How are antibodies separated into classes?
Antworten
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By their heavy chain
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By their light chain
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By their constant region
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By their variable region
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By what sort of pathogen they are against
Frage 14
Frage
What is the function of membrane bound antibodies?
Antworten
-
Recognise antigens
-
Activate B cells
-
Activate T cells
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Opsonisation
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Neutralization of pathogens
Frage 15
Frage
Which type of antibody activates complement?
Antworten
-
Membrane bound antibodies
-
Secreted antibodies
Frage 16
Frage
Which cells require an antigen presenting cell to activate them?
Antworten
-
T cells
-
B cells
Frage 17
Frage
Which of the following cells can act as antigen presenting cells?
Antworten
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Dendritic cells
-
Macrophages
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Natural killer cells
-
Plasma B cells
-
Mast cells
Frage 18
Frage
Which cells express MHCI?
Antworten
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All nucleated cells
-
T helper cells
-
Antigen presenting cells
-
Plasma B cells
-
Natural killer cells
Frage 19
Frage
Which of the following cells recognised MHCII?
Antworten
-
CD8 cells
-
CD4 cells
Frage 20
Frage
Where within the antigen presenting cell is the MHC produced?
Antworten
-
Endoplasmic reticulum
-
Golgi body
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Ribosome
-
Nucleus
Frage 21
Frage
Where is the MCHII complex combined with the antigenic peptides?
Antworten
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Endosome
-
Endoplasmic reticulum
-
Golgi body
-
Vesicle
Frage 22
Frage
The T cell is activated when it detects the MHC-antigen complex. True or false?
Antworten
- True
- False
Frage 23
Frage
Which types of hypersensitivity reaction are mediated by antibodies?
Antworten
-
I
-
II
-
III
-
IV
Frage 24
Frage
Which type of hypersensitivity reaction is mediated by IgE?
Antworten
-
I
-
II
-
III
-
IV
Frage 25
Frage
Which of the following are examples of hypersensitivity reactions that are mediated by IgE?
Antworten
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Asthma
-
Pollen allergy
-
SLE
-
Myasthenia Gravis
-
Grave's disease
-
Type I diabetes
-
Psoriasis
Frage 26
Frage
In a type I hypersensitivity reaction, what needs to happen to the antibodies on repeat exposure for there to be a hypersensitivity reaction?
Antworten
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Clonal expansion
-
Cross-linking
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Breaking of the disulphide bonds
-
Dimer formation
Frage 27
Frage
Grave's disease is an example of a type II hypersensitivity reaction. What are type II hypersensitivity reactions mediated by?
Antworten
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IgE
-
Antibodies other than IgE
-
T helper cells
-
T cytotoxic cells
-
Natural killer cells
Frage 28
Frage
What is another example of a type II hypersensitivity reaction?
Antworten
-
Myasthenia Gravis
-
Asthma
-
Type I diabetes
-
SLE
-
Coeliac disease
Frage 29
Frage
How do the antibodies in type II hypersensitivity reactions cause disease?
Antworten
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They block the receptor
-
They activate the receptor
-
They destroy the receptor
-
They act as inverse agonists
Frage 30
Frage
In which type of hypersensitivity reaction after immune complexes formed?
Antworten
-
I
-
II
-
III
-
IV
Frage 31
Frage
Why are immune complexes a problem?
Antworten
-
Because they can get stuck in the body
-
Because they promote autoimmune destruction of cells
-
Because they promote other hypersensitivity reactions
-
Because they increase the viscosity of blood which can cause thrombosis
-
Because they cause lymphadenopathy
Frage 32
Frage
Antibodies in immune complexes can activate complement. True or false?
Antworten
- True
- False
Frage 33
Frage
What are type IV hypersensitivity reactions mediated by?
Antworten
-
T helper cells
-
Antibodies other than IgE
-
IgE
-
T killer cells
Frage 34
Frage
Which of the following are examples of type IV hypersensitivity reactions?
Antworten
-
Coeliac disease
-
Type I diabetes
-
SLE
-
Asthma
-
Haemolytic disease of the new born
Frage 35
Frage
How do T helper cell cause hypersensitivity reactions?
Antworten
-
Cytokine production that activates macrophages and T cytotoxic cells
-
Activation of natural killer cells
-
Activation of mast cells causing release of histamine
-
Formation of immune complexes which activate complement
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