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Quiz von ACAPUN INSTITUTE, aktualisiert more than 1 year ago
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Erstellt von ACAPUN INSTITUTE
vor mehr als 2 Jahre
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Frage 1
Frage
Which of the following drugs is useful in treating dermatologic manifestations of an allergic response?
Antworten
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a. Diazepam
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b. Atropine
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c. Hexylresorcinol
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d. Chlorpheniramine
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e. Phenoxybenzamine
Frage 2
Frage
Cimetidine is used therapeutically to
Antworten
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a. Stimulate respiration
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b. Protect against anaphylaxis
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c. Decrease gastric acid secretion
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d. Hasten excretion of barbiturates
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e. Dilate smooth muscles of the bronchioles
Frage 3
Frage
Gastric acid secretion has been shown to be most effectively reduced with the use of
Antworten
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a. Adrenal steroids
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b. Anticholinergic drugs
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c. Serotonin antagonists
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d. H1-histamine receptor antagonists
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e. H2-histamine receptor antagonists
Frage 4
Frage
Drug-mediated inhibition of H2-histamine receptors is most useful in treating
Antworten
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a. Asthma
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b. Anaphylaxis
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c. Contact dermatitis
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d. Gastric hyperacidity
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e. Localized allergic reactions
Frage 5
Frage
Which of the following antihistamines is most commonly used as preoperative medication?
Antworten
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a. Meclizine
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b. Cyclizine
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c. Promethazine
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d. Dimenhydrinate
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e. Chlorpheniramine
Frage 6
Frage
Use of diphenhydramine (Benadryl) in controlling the symptoms of parkinsonism is based upon which of the following effects?
Antworten
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a. Anticholinergic
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b. Local anesthetic
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c. Adrenergic-blocking
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d. CNS depressant on the midbrain
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e. Stimulant to dopaminergic nerves in the basal ganglia
Frage 7
Frage
The mechanism of action of H1 antihistamines is
Antworten
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a. MAO enzyme inhibition
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b. competitive antagonism
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c. physiologic antagonism
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d. noncompetitive antagonism
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e. inhibition of release of bound histamine
Frage 8
Frage
Which of the following drugs is often used to treat trigeminal neuralgia?
Antworten
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a. clonazepam
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b. carbamazepine
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c. acetazolamine
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d. succinylcholine
Frage 9
Frage
The use of epinephrine for local hemostasis during surgery might result in
Antworten
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a. hypoglycemia
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b. cardiac arrthymia
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c. an acute asthma attack
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d. a drastic drop in blood pressure
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e. any of the above
Frage 10
Frage
The highest risk associated with use of oral contraceptives is
Antworten
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a. hepatic necrosis
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b. permanent sterility
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c. cancer of the breast
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d. cancer of the uterus
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e. thromboembolic disorders
Frage 11
Frage
Factors common to all forms of drug abuse include EXCEPT
Antworten
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a. miosis
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b. tolerance
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c. physical dependence
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d. psychological dependence
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e. any of the above
Frage 12
Frage
Alcoholic euphoria results from
Antworten
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a. increased activity of the cerebellum
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b. increased activity of the cerebral areas
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c. increased activity of the spinal synapses
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d. decreased activity of the medullary centers
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e. removal of inhibitory activity of the cortex
Frage 13
Frage
Sulfonyl ureas cause insulin secretion by
Antworten
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a. adrenergic simulation
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b. cholinergic stimulation
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c. direct stimulation of pancreatic beta cells
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d. dependent of glucosa
Frage 14
Frage
If a patient requiring an extraction reports that he is on dicoumarol therapy, the laboratory test most valuable in evaluating the surgical risk is
Antworten
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a. clotting time
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b. bleeding time
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c. sedimentation rate
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d. complete blood cell count
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e. plasma prothrombin time
Frage 15
Frage
A drug has a half-life of 4 hours. If 2 gms are given every 4 hrs what will be the amount in gms in the body immediately after the third dose?
Antworten
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a. 1.5
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b. 2.0
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c. 3.5
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d. 4.0
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e. 6.0
Frage 16
Frage
Which of the following combinations represents acceptable agonistantagonist pairs in antidotal therapy?
Antworten
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a. morphine-naloxone
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b. dicoumarol-protamine
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c. warfarin-phenylbutazone
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d. carbon monoxide-carbon dioxide
Frage 17
Frage
The various insulin preparations useful in the treatment of diabetes mellitus differ primarily in
Antworten
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a. locus of action
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b. mechanism of action
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c. mode of transformation
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d. onset and duration of action
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e. none of the above
Frage 18
Frage
Displacement of a drug from protein binding sites is expected to increase the
Antworten
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a. drug effect observed
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b. duration of drug effect
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c. dose required for a given effect
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d. none of the above
Frage 19
Frage
In an addisonian crisis (hypoaldosteronism) resulting from stress from a minor dental procedure, the patient should be treated immediately with
Antworten
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a. 0.5 ml norepinephrine
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b. 5 mg. prednisolone acetate
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c. 1% triamcinolone acetonide
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d. 0.5 ml, 1:1000 epinephrine
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e. 2 ml (100 mg) hydrocortisone hemisuccinate
Frage 20
Frage
Drug A inhibits the biotransformation of Drug B. The duration of action of drug B in the presence of drug A will usually be
Antworten
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a. shortened
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b. prolonged
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c. unchanged
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d. equal
Frage 21
Frage
In which of the following groups of drugs is there the most consistency in chemical structure?
Antworten
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a. diuretics
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b. antiepileptics
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c. local anesthetics
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d. general anesthetics
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e. nonbarbiturate sedatives
Frage 22
Frage
Cimetidine is administered to
Antworten
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a. aid in sleeping
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b. relieve asthma
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c. inhibit gastric secretion
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d. relieve cold and flu symptoms
Frage 23
Frage
Which of the following anticancer drugs can be classified as an antimetabolite?
Antworten
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a. cisplatin
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b. lomustine
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c. vincristine
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d. methotrexate
Frage 24
Frage
Which of the following hormones acts to elevate blood concentration of ionic calcium?
Antworten
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a. glucagon
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b. parathyroid
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c. aldosterone
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d. thyrotropin
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e. thyrocalcitonin
Frage 25
Frage
Disorientation, confusion, and hallucinations resulting from an overdose of scopolamine are most efficaciously treated by administering
Antworten
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a. atropine
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b. levodopa
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c. acetylcholine
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d. physostigmine
Frage 26
Frage
Developed hyporeactivity to a drug is
Antworten
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a. tolerance
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b. antagonism
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c. detoxification
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d. desensitization
Frage 27
Frage
Absorption of a drug from the intramuscular site of administration may be slowed by
a. excercise
b. vasoconstriction
c. the presence of congestive heart failure
d. administering the drug as an insoluble complex
Antworten
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1. a and b
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2. b only
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3. b, c, and d
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4. b and d
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5. all of the above
Frage 28
Frage
Salicylism includes which of the following?
a. nausea
b. tinnitus
c. vomiting
d. gastrointestinal bleeding
Antworten
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1. a, b, and c
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2. a, b, and d
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3. a and c only
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4. b, c, and d
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5. all of the above
Frage 29
Frage
Which of the following are important criteria for the adequate clinical evaluation of a new drug?
a. comparison with a placebo
b. evaluation of side effects
c. utilization of control groups
d. comparison with a standard drug
e. double blind experimental design
Antworten
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1. a, b, c, and d
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2. a, b, d, and e
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3. a, c, d, and e
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4. b, c, and e
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5. b, d and e only
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6. all of the above
Frage 30
Frage
Each of the following agents has a long duration of action due to the presence of liver generated active metabolites EXCEPT
Antworten
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a. diazepam
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b. oxazepam
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c. flurazepam
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d. chlordiazepoxide
Frage 31
Frage
Each of the following statements relates to the general aspects of toxicology EXCEPT
Antworten
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a. most drugs exert a single action
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b. toxicity is both time and dose dependent
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c. toxicity can be due to overdosage of a drug
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d. symptoms of toxicity can be anything ranging from nausea to death
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e. for some drugs, even a minimal concentration can be harmful
Frage 32
Frage
The central actions of ethyl alcohol are not synergistic with which of the following?
Antworten
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a. diazepam
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b. meperidine
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c. pentobarbital
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d. chlorpromazine
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e. methylphenidate
Frage 33
Frage
A heroin dependent patient should not be given nalbuphine (Nubain) for pain because
Antworten
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a. it has no analgesic properties
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b. it may produce respiratory depression
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c. as a mixed agonist-antagonist, it can elicit withdrawal symptoms
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d. the high abuse potential of nalbuphine may add to the patient's problems
Frage 34
Frage
All of the following methods of drug biotransformation are classified as synthetic except:
Antworten
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a. N-alkylation
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b. O-dealkylation
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c. sulfate conjugation
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d. glucuronide conjugation
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