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Quiz von ACAPUN INSTITUTE, aktualisiert more than 1 year ago
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Frage 1
Frage
Atropine and propantheline exert their effects on peripheral structures by
Antworten
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a. preventing release of acetylcholine
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b. preventing synthesis of acetylcholine
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c. enhancing destruction of acetylcholine
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d. competeing with acetylcholine for receptor sites
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e. producing physiologic effects opposite to those of acetylcholine
Frage 2
Frage
Neostigmine produces its effect by physostigmine. These differ from the insecticides and nerve gases listed below in that they are reversible and can be used clinically; the latter are irreversible
Antworten
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a. depressing acetylcholinesterase release
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b. inhibiting acetylcholinesterase activity
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c. increasing the rate of acetylcholine synthesis
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d. acting like acetylcholine at ganglionic sites
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e. increasing the amount of acetylcholine released from nerve terminals
Frage 3
Frage
Organophosphate insecticides and nerve gases inhibit the action of which of the following enzymes?
Antworten
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a. adenylate cyclase
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b. monoamine oxidase
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c. phosphodiesterase
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d. acetylcholinesterase
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e. carbonic anhydrase
Frage 4
Frage
Drugs which are additive with or potentiate the effects of acetylcholine include
(a) methacholine
(b) scopolamine
(c) pralidoxime
(d) neostigmine
(e) pilocarpine
Antworten
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1. (a), (b), and (c)
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2. (a), (c), and (d)
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3. (a), (d) and (e)
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4. (b), (d), and (e)
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5. (c), (d) and (e)
Frage 5
Frage
Which of the following drugs is best to administer after poisoning by an organophosphate cholinesterase inhibitor?
Antworten
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a. atropine
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b. phenytoin
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c. pralidoxime
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d. propantheline
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e. phenobarbital
Frage 6
Frage
Which of the following compounds is a ganglionic blocking agent?
Antworten
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a. curarine
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b. edrophonium
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c. mecamylamine
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d. succinylcholine
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e. gallamine triethodide
Frage 7
Frage
Which of the following acts by antagonizing cholinesterase?
Antworten
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a. atropine
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b. muscarine
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c. neostigmine
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d. pilocarpine
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e. acetylcholine
Frage 8
Frage
When neostigmine is administered before acetylcholine, the action of acetylcholine will be
Antworten
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a. blocked
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b. enhanced and prolonged
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c. less intense and of shorter duration
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d. none of the above. The action of acetylcholine is not affected by neostigmine
Frage 9
Frage
Neostigmine can stimulate denervated skeletal muscle because it
Antworten
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a. is a congener of acetylcholine
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b. is a competitive blocking agent
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c. has no effect on acetylcholinesterase
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d. is more potent than diisopropylfluorophosphate
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e. is capable of acting directly on the end-plate
Frage 10
Frage
Which of the following is used to prevent laryngospasm?
Antworten
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a. atropine
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b. epinephrine
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c. diazepam (Valium)
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d. neostigmine (Prostigmine)
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e. succinylcholine (Anectine)
Frage 11
Frage
In treating xerostomia, which of the following might be prescribed?
Antworten
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a. atropine
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b. ephedrine
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c. neostigmine
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d. scopolamine
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e. mecamylamine
Frage 12
Frage
Which of the following drugs is most likely to dry secretions in the oral cavity?
Antworten
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a. diazepam
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b. promethazine
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c. physostigmine
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d. propantheline
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e. diphenhydramine
Frage 13
Frage
The most useful drug to induce salivation is one which has properties that are
Antworten
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a. adrenergic
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b. cholinergic
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c. ganglionic blocking
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d. adrenergic blocking
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e. cholinergic blocking
Frage 14
Frage
Drugs that are commonly used in the control of excessive salivation include
(a) meprobamate
(b) atropine
(c) methantheline
(d) codeine
(e) chlorpromazine
Antworten
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1. (a) and (b) only
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2. (a), (b), and (c)
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3. (b) and (c) only
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4. (b), (c), and (d)
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5. (d) and (e)
Frage 15
Frage
Drugs that are commonly used in the control of excessive salivation include
(a) meprobamate
(b) atropine
(c) methantheline
(d) codeine
(e) chlorpromazine
Antworten
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1. (a) and (b) only
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2. (a), (b), and (c)
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3. (b) and (c) only
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4. (b), (c), and (d)
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5. (d) and (e)
Frage 16
Frage
Tachycardia in a patient administered with atropine or scopolamine results from
Antworten
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a. release of adrenal catecholamines
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b. blockade of vagus nerve activity
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c. blockade of the nicotinic cholinergic receptor
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d. stimulation of the alpha adrenergic receptor
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e. stimulation of the beta adrenergic receptor
Frage 17
Frage
All of the following are possible effects of cholinomimetic drugs except
Antworten
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a. mydriasis
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b. bradycardia
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c. increased peristalsis
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d. stimulation of sweat glands
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e. increased secretion by bronchial glands
Frage 18
Frage
A paralyzing dose of succinylcholine initially elicits
Antworten
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a. CNS stimulation
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b. CNS depression
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c. decreased salivation
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d. muscle fasiculation
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e. extrapyramidal reactions
Frage 19
Frage
Based on its known mechanism and sites of action, scopolamine should theoretically be useful in
(a) treatment of peptic ulcer
(b) providing euphoria and amnesia prior to surgery
(c) relieving bronchoconstriction
(d) relieving some of the symptoms of Parkinson disease
(e) visualization of the retina
Antworten
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1. (a), (b), (d) and (e)
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2. (a), (b), and (e) only
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3. (a),and (c)
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4. (b) and (e) only
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5. All of the above
Frage 20
Frage
Symptoms of poisoning by an organophosphate insecticide include all of the following except:
Antworten
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a. skeletal muscle fasiculation
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b. excessive salivation
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c. bronchoconstriction
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d. hot, dry skin
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e. diarrhea
Frage 21
Frage
All of the following symptoms are associated with neostigmine poisoning except
Antworten
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a. diarrhea
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b. salivation
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c. convulsions
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d. bonchiolar constriction
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e. skeletal muscle paralysis
Frage 22
Frage
Symptoms of atropine poisoning in man include
(a) decreased intraocular pressure
(b) burning dry mouth
(c) nausea, vomiting and diarrhea
(d) hyperthermia
(e) orthostatic hypotension
Antworten
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1. (a) and (c)
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2. (b) and (d)
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3. (b), (d), and (e)
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4. (d) and (e)
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5. All of the above
Frage 23
Frage
The most likely signs or symptoms of overdosage with atropine are
Antworten
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a. CNS excitation and tachycardia
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b. intestinal cramps and diarrhea
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d. ptyalism and increased sweating
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e. constriction of the pupils and blurring of vision
Frage 24
Frage
Disorientation, confusion and hallucinations resulting from an overdose of scopolamine are most efficaciuosly treated by administering
Antworten
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a. atropine
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b. levodopa
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c. acetylcholine
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d. physostigmine
Frage 25
Frage
The immediate cause of death from irreversible cholinesterase inhibitors is
Antworten
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a. shock
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b. convulsion
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c. cardiac arrhythmia
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d. respiratory paralysis
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e. dehydration from vomiting and diarrhea
Frage 26
Frage
Each of the following is a symptom of cholinergic crisis except
Antworten
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a. bradycardia
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b. lacrimation
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c. vasoconstriction
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d. extreme salivation
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e. weakness of voluntary muscles
Frage 27
Frage
Succinylcholine is a short-acting neuromuscular junction blocking agent useful for providing a brief paralysis to aid in intubating patients. It is short-acting because
Antworten
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a. it is subject to rapid metabolism in the liver
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b. it rapidly redistributes away from the NMJ
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c. it is subject to inactivation by plasma esterases
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d. it undergoes rapid inactivation in the GI tract
Frage 28
Frage
Atropine-like drugs are classed as
Antworten
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a. anti-adrenergic
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b. cholinomimetic
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c. sympatholytic
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d. anti-cholinergic
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e. sympathomimetic
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