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Quinidine is principally used to treat
Frage 2
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Quinidine is used to treat
Frage 3
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Verapamil is most efficacious in the treatment of
Frage 4
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Which of the following drugs is most useful in treating or preventing angina pectoris?
Antworten
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a. Digitalis
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b. Quinidine
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c. Propranolol
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d. Procainamide
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e. Pentobarbital
Frage 5
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Each of the following drugs can be used in the prevention and treatment of angina pectoris EXCEPT
Frage 6
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All of the following drugs are useful in the treatment of hypertension EXCEPT
Antworten
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a. Ephedrine
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b. Reserpine
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c. Methyldopa
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d. Thiazide diuretics
Frage 7
Frage
Digitalis is useful in the treatment of which of the following conditions?
Frage 8
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All of the following drugs are useful in the treatment of cardiac arrhythmias EXCEPT
Antworten
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a. Digitalis
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b. Lidocaine
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c. Phenytoin
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d. Procainamide
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e. Aminophylline
Frage 9
Frage
The drug of choice for initial therapy for mild hypertension is
Antworten
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a. Reserpine
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b. Guanethidine
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c. Phenobarbital
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d. Chlorothiazide
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e. Alpha-methyldopa
Frage 10
Frage
Which of the following antihypertensives are usually reserved for treatment of severe hypertension?
Antworten
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a. Sedatives and reserpine
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b. Thiazide diuretics and reserpine
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c. Sedatives and thiazide diuretics
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d. Guanethidine and ganglionic blocking agents
Frage 11
Frage
Which of the following beta-adrenergic receptor blocking agents is thought to be cardioselective?
Antworten
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a. Nadolol
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b. Timolol
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c. Metoprolol
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d. Propranolol
Frage 12
Frage
Antiarrhythmic drugs, such as quinidine, suppress certain cardiac arrhythmias by
Antworten
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a. Stimulating the beta-adrenergic receptor
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b. Suppressing cardiac ATP-ase activity
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c. Increasing ectopic pacemaker activity
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d. Increasing the refractory period of cardiac muscle
Frage 13
Frage
Most drugs useful in the treatment of cardiac arrhythmias act primarily by
Antworten
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a. Blocking Purkinje fibers
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b. Blocking the alpha-adrenergic receptor
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c. Suppressing SA node impulse formation
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d. Causing a positive inotropic effect
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e. Increasing the refractory period of cardiac muscle
Frage 14
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The most important pharmacologic action of drugs that suppress cardiac arrhythmias is
Antworten
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a. Blockade of the vagus nerve
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b. Stimulation of cardiac ATP-ase activity
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c. Blockade of the Beta-adrenergic receptor
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d. Stimulation of the beta-adrenergic receptor
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e. Increased refractory period of cardiac muscle
Frage 15
Frage
Lidocaine produces its antiarrhythmic effects by
Antworten
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a. Increasing AV conduction
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b. Decreasing cardiac excitability
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c. Increasing cardiac conduction velocity
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d. Increasing spontaneous pacemaker activity
Frage 16
Frage
When digitalis is used in atrial fibrillation, the therapeutic objective is to
Antworten
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a. Abolish cardiac decompensation
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b. Inhibit vagal impulses to the heart
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c. Decrease the rate of A-V conduction
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d. Increase the rate of cardiac repolarization
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e. Produce a decrease in the rate of atrial contraction
Frage 17
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Nitroglycerin dilates the coronary arteries in angina pectoris by
Antworten
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a. Decreasing the heart rate reflexly
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b. Increasing the metabolic work of the myocardium
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c. Direct action on smooth muscle in the vessel walls
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d. Increasing the effective refractory period in the atrium
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e. Blocking beta-adrenergic receptors
Frage 18
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Propranolol is of value in treating angina pectoris because it
Antworten
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a. Has a direct action on vascular smooth muscle
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b. Blocks autoregulatory mechanisms in the heart
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c. Inhibits oxygen metabolism in cardiac cells
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d. Provides relief within seconds of an acute anginal attack
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e. Prevents chronotropic responses to endogenous epinephrine emotions and exercise
Frage 19
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Administration of angiotensin results in
Antworten
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a. Anti-inflammatory effects
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b. Antihistaminic effects
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c. Increased blood pressure
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d. Increased heart rate
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e. A sedative effect
Frage 20
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The primary antihypertensive effect of captopril (Capoten) is due to accumulation of
Frage 21
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Administration of angiotensin results in
Antworten
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a. A sedative effect
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b. Increased heart rate
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c. Increased blood pressure
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d. Antihistaminic effects
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e. Anti-inflammatory effects
Frage 22
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Which of the following is NOT characteristic of the thiazide diuretics?
Antworten
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a. Increase renal excretion of sodium and chloride
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b. Increase renal excretion of potassium
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c. Increase the toxicity of digitalis
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d. Exacerbate existing diabetes
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e. Cause hypokalemia
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f. Cause hypoglycemia
Frage 23
Frage
The most useful diuretic drugs act by
Antworten
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a. Increasing the glomerular filtration rate
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b. Decreasing the renal reabsorption of sodium
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c. Decreasing the renal excretion of chloride
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d. Increasing the renal reabsorption of potassium
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e. Increasing the secretion of antidiuretic hormone
Frage 24
Frage
Which of the following drugs act by inhibiting renal reabsorption of sodium?
Antworten
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a. Urea
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b. Chlorothiazide
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c. Theophylline
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d. digitalis glycosides
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e. Procainamide
Frage 25
Frage
Digoxin exerts its positive inotropic effect by
Antworten
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a. Activation of adenylcyclase
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b. Inhibition of phosphodiesterase
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c. An agonist effect of beta-receptors
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d. Inhibition of Na+, K+ ATPASE leading to increased calcium influx
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e. Decreasing the amount of calcium available for excitationcontraction coupling
Frage 26
Frage
Digitoxin is effective in the treatment of cardiac failure because it
Antworten
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a. Is primarily a diuretic
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b. Reduces the ventricular rate
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c. Decreases abnormal cardiac rhythms
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d. Produces peripheral vasoconstriction
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e. Has a positive cardiac inotropic action
Frage 27
Frage
The primary action of therapeutic doses of digitalis on cardiac muscle is an increase in
Antworten
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a. Force of contraction
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b. Ventricular excitability
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c. Refractory period of the atrial muscle
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d. Refractory period of the ventricular muscle
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e. Rate of conduction of impulse to the muscle
Frage 28
Frage
The beneficial effects of digitalis in congestive heart failure result in part from the fact that digitalis causes
a. A decrease in end-diastolic volume
b. A decrease in end-diastolic pressure
c. An increase in stroke volume and cardiac output
d. A decrease in central venous pressure
e. A decrease in rate of the hear where tachycardia exists
Antworten
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a) (a), (b) and (c)
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b) (a) and (c) only
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c) (c) and (d)
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d) (e) only
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e) All of the above
Frage 29
Frage
The cardiac glycosides will increase the concentration of which ion in an active heart muscle?
Antworten
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a. Sodium
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b. Bromide
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c. Calcium
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d. Chloride
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e. Potassium
Frage 30
Frage
Which of the following ions augments the inotropic effect of digitalis?
Antworten
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a. Sodium
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b. Lithium
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c. Calcium
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d. Chloride
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e. Magnesium
Frage 31
Frage
In the treatment of congestive heart failure, digitalis glycosides generally decrease all of the following EXCEPT
Frage 32
Frage
The mechanism of action of prazosin, an antihypertensive agent is to
Antworten
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a. Block beta-adrenergic receptors
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b. Inhibit formation of angiotensin II
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c. Inhibit nerve-induced release of norepinephrine
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d. Stimulate central inhibitory alpha-adrenergic receptors
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e. Inhibit the postsynaptic of norepinephrine on vascular smooth muscle
Frage 33
Frage
Which of the following owes a significant amount of its antihypertensive effect to a central action?
Antworten
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a. Methyldopa
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b. Metoprolol
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c. Hydralazine
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d. Propranolol
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e. Guanethidine
Frage 34
Frage
Which of the following drugs is thought to reduce arterial blood pressure by activating alpha receptors in the vasomotor center of the medulla?
Antworten
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a. Prazosin
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b. Clonidine
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c. Propranolol
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d. Guanethidine
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e. Chlorothiazide
Frage 35
Frage
Propranolol (Inderal) can be useful in the treatment of hypertension because it blocks
Antworten
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a) (a) and (b)
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b) (a) and (d)
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c) (b), (c) and (d)
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d) (c), (d) and (e)
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e) (c) and (e) only
Frage 36
Frage
One of the proposed mechanisms of the antihypertensive effect of beta-adrenergic receptor blocking agents is
Frage 37
Frage
Selective beta-1 adrenergic agonists will produce which of the following effects?
Antworten
-
a. Glycogenolysis
-
b. Increased cardiac output
-
c. Decreased diastolic pressure
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d. Decreased peripheral resistance
-
e. Relaxation of bronchial smooth muscle
Frage 38
Frage
Ototoxicity with deafness may encountered occasionally in patients taking which of the following diuretic agents?
Antworten
-
a. Osmotic
-
b. Thiazide
-
c. Mercurial
-
d. High-ceiling
Frage 39
Frage
Ototoxicity with deafness may encountered occasionally in patients taking which of the following diuretic agents?
Antworten
-
a. Osmotic
-
b. Thiazide
-
c. Mercurial
-
d. High-ceiling
Frage 40
Frage
Symptoms of digitalis toxicity include all of the following EXCEPT
Antworten
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a. Extrasystoles
-
b. Nausea and vomiting
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c. Yellow-green vision
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d. A-V conduction block
-
d. Chlorothiazide
-
e. Acetylsalicylic acid